Corticosterone Preexposure Increases NF-κB Translocation and Sensitizes IL-1β Responses in BV2 Microglia-Like Cells

Mineralocorticoid Receptor Deficiency in Macrophages Inhibits Neointimal Hyperplasia and Suppresses Macrophage Inflammation Through SGK1-AP1/NF-κB PathwaysSignificance

(2016) Jian-Yong Sun et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Toll-Interleukin 1 Receptor domain-containing adaptor protein positively regulates BV2 cell M1 polarization

(2016) Leilei Gong et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

MicroRNA-7 targets Nod-like receptor protein 3 inflammasome to modulate neuroinflammation in the pathogenesis of Parkinson’s disease

(2016) Yan Zhou et al.   Molecular Neurodegeneration

Gene Expression Control by Glucocorticoid Receptors during Innate Immune Responses

(2016) Andre Machado Xavier et al.   Frontiers in Endocrinology

Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands

(2015) Amitabh Das et al.   BMC GENOMICS

Chronic stress exacerbates neuronal loss associated with secondary neurodegeneration and suppresses microglial-like cells following focal motor cortex ischemia in the mouse

(2015) Kimberley A. Jones et al.   BRAIN BEHAVIOR AND IMMUNITY

Inflammasome-Induced IL-1  Secretion in Microglia Is Characterized by Delayed Kinetics and Is Only Partially Dependent on Inflammatory Caspases

(2015) S. M. Burm et al.   JOURNAL OF NEUROSCIENCE

Stress and the brain: individual variability and the inverted-U

(2015) Robert M Sapolsky   NATURE NEUROSCIENCE

A combined cumulative threshold spectra and digital reconstruction analysis reveal structural alterations of microglia within the prefrontal cortex following low-dose LPS administration

(2015) R. Kongsui et al.   NEUROSCIENCE

Social defeat promotes a reactive endothelium in a brain region-dependent manner with increased expression of key adhesion molecules, selectins and chemokines associated with the recruitment of myeloid cells to the brain

(2015) C.M. Sawicki et al.   NEUROSCIENCE

Relationship of PTSD Symptoms With Combat Exposure, Stress, and Inflammation in American Soldiers

(2014) M. W. Groer et al.   Biological Research for Nursing

Microglial NLRP3 inflammasome activation mediates IL-1β-related inflammation in prefrontal cortex of depressive rats

(2014) Ying Pan et al.   BRAIN BEHAVIOR AND IMMUNITY

Greater inflammatory activity and blunted glucocorticoid signaling in monocytes of chronically stressed caregivers

(2014) Gregory E. Miller et al.   BRAIN BEHAVIOR AND IMMUNITY

Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation

(2014) Rocío M de Pablos et al.   Journal of Neuroinflammation

Glucocorticoids Increase Excitotoxic Injury and Inflammation in the Hippocampus of Adult Male Rats

(2014) Shawn F. Sorrells et al.   NEUROENDOCRINOLOGY

Toll-like receptor 4: innate immune regulator of neuroimmune and neuroendocrine interactions in stress and major depressive disorder

(2014) JiaJun Liu et al.   Frontiers in Neuroscience

Re-establishment of Anxiety in Stress-Sensitized Mice Is Caused by Monocyte Trafficking from the Spleen to the Brain

(2013) Eric S. Wohleb et al.   BIOLOGICAL PSYCHIATRY

Stress-induced glucocorticoids as a neuroendocrine alarm signal of danger

(2013) Matthew G. Frank et al.   BRAIN BEHAVIOR AND IMMUNITY

CRP, IL-6 and depression: A systematic review and meta-analysis of longitudinal studies

(2013) Vyara Valkanova et al.   JOURNAL OF AFFECTIVE DISORDERS

The biology of the glucocorticoid receptor: New signaling mechanisms in health and disease

(2013) Robert H. Oakley et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The inflamed axis: The interaction between stress, hormones, and the expression of inflammatory-related genes within key structures comprising the hypothalamic–pituitary–adrenal axis

(2013) Cara M. Hueston et al.   PHYSIOLOGY & BEHAVIOR

Chronic exposure to exogenous glucocorticoids primes microglia to pro-inflammatory stimuli and induces NLRP3 mRNA in the hippocampus

(2013) Matthew G. Frank et al.   PSYCHONEUROENDOCRINOLOGY

The mineralocorticoid receptor-p38MAPK-NFκB or ERK-Sp1 signal pathways mediate aldosterone-stimulated inflammatory and profibrotic responses in rat vascular smooth muscle cells

(2012) Chuan-jiang Zhu et al.   ACTA PHARMACOLOGICA SINICA

Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells

(2012) Boonrat Chantong et al.   Journal of Neuroinflammation

Prenatal stress causes alterations in the morphology of microglia and the inflammatory response of the hippocampus of adult female mice

(2012) Yolanda Diz-Chaves et al.   Journal of Neuroinflammation

Corticosterone suppresses the proliferation of BV2 microglia cells via glucocorticoid, but not mineralocorticoid receptor

(2012) Yoshihiko Nakatani et al.   LIFE SCIENCES

Glucocorticoid receptor dimerization is required for proper recovery of LPS-induced inflammation, sickness behavior and metabolism in mice

(2012) M N Silverman et al.   MOLECULAR PSYCHIATRY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

NLRP3 Inflammasome: Key Mediator of Neuroinflammation in Murine Japanese Encephalitis

(2012) Deepak Kumar Kaushik et al.   PLoS One

IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures

(2011) Annamaria Vezzani et al.   BRAIN BEHAVIOR AND IMMUNITY

Glucocorticoids mediate stress-induced priming of microglial pro-inflammatory responses

(2011) Matthew G. Frank et al.   BRAIN BEHAVIOR AND IMMUNITY

Evidence that Microglia Mediate the Neurobiological Effects of Chronic Psychological Stress on the Medial Prefrontal Cortex

(2011) M. Hinwood et al.   CEREBRAL CORTEX

Mechanisms of cytokine secretion: A portfolio of distinct pathways allows flexibility in cytokine activity

(2011) Erwin Hans Duitman et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Glucocorticoids Sensitize the Innate Immune System through Regulation of the NLRP3 Inflammasome

(2011) John M. Busillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NFκB and glucocorticoid receptor activity in steroid resistance

(2011) Charlotte Dawson et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Inhibition of Histone Deacetylase 2 Expression by Elevated Glucocorticoid Receptor β in Steroid-resistant Asthma

(2010) Ling-bo Li et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cortisol Exerts bi-phasic Regulation of Inflammation in Humans

(2010) Mark P. Yeager et al.   Dose-Response

Nuclear factor-κB/p65 responds to changes in the Notch signaling pathway in murine BV-2 cells and in amoeboid microglia in postnatal rats treated with the γ-secretase complex blocker DAPT

(2010) Q. Cao et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Major Stress Hormones Suppress the Response of Macrophages Through Down-Regulation of TLR2 and TLR4

(2010) Quan Du et al.   JOURNAL OF SURGICAL RESEARCH

Sulforaphane suppresses LPS-induced inflammation in primary rat microglia

(2009) Lars-Ove Brandenburg et al.   INFLAMMATION RESEARCH

Stress and disorders of the stress system

(2009) George P. Chrousos   Nature Reviews Endocrinology

Repression of DNA-binding dependent glucocorticoid receptor-mediated gene expression

(2009) K. A. Muzikar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Associations of Depression With C-Reactive Protein, IL-1, and IL-6: A Meta-Analysis

(2009) M Bryant Howren et al.   PSYCHOSOMATIC MEDICINE

Corticosterone Levels in the Brain Show a Distinct Ultradian Rhythm but a Delayed Response to Forced Swim Stress

(2008) Susanne K. Droste et al.   ENDOCRINOLOGY

Exaggerated sickness behavior and brain proinflammatory cytokine expression in aged mice in response to intracerebroventricular lipopolysaccharide

(2007) Y. Huang et al.   NEUROBIOLOGY OF AGING