Article
Engineering, Environmental
Chenyang Bi, Xinke Wang, Hongwan Li, Xiaofeng Li, Ying Xu
Summary: Phthalate and alternative plasticizers are among the most abundant indoor pollutants and can directly transfer from source products to dust, with various factors such as Koa, emission parameter and dust layer characteristics influencing the concentration and kinetics of this transfer. Minimizing the use of SVOC-containing products and regular vacuuming are effective strategies to reduce young children's exposure to SVOCs.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Environmental Sciences
Zongrui Li, Chang He, Jing Yang, Tianrui Gao, Yichao Huang, Lin Tao
Summary: In this study, traditional and novel plasticizers were analyzed in indoor dust from an e-waste recycling area. The levels of these chemicals were influenced by local e-waste activities, as supported by the levels of PBDEs. However, the correlations between chemical levels and indicators suggest that dust might not be the primary source of these plasticizers. The estimated human exposures through dust ingestion indicate negligible health risks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Engineering, Environmental
Yayun Zhang, Jianhua Li, Guanyong Su
Summary: This study utilized liquid chromatography coupled with a quadrupole-Orbitrap mass spectrometer to analyze indoor dust samples from Nanjing City, China, and found significant levels of citrate acid esters (CAEs) as phthalate substitute plasticizers. The research also identified correlation relationships between the CAEs and other common organic contaminants in dust.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Construction & Building Technology
Jeong-In Jeon, Hye-Won Lee, Si-Hyun Park, Dan-Ki Yoon, Jeong-Il Lee, Cheol-Min Lee
Summary: This study proposes an organic film-based method to assess semivolatile organic compound (SVOC) exposure in indoor environments. Various phthalate exposure pathways were examined in children and adults, and the findings provide important baseline data for future research in health risk assessments and SVOC exposure utilizing organic films.
Article
Construction & Building Technology
Lingyi Kang, Sijing Wu, Ke Liu, Xinke Wang, Xiaojun Zhou
Summary: A porous media model was proposed to characterize the mass transfer mechanism of phthalates from sources to settled dust via different migration pathways. Simulation results showed that dust loading can control the mass transfer of phthalates and parameters like solid diffusion coefficient and K-oa values significantly affect the concentration of phthalates in settled dust.
BUILDING AND ENVIRONMENT
(2021)
Article
Environmental Sciences
A. Exposito, B. Markiv, L. Ruiz-Azcona, M. Santibanez, I Fernandez-Olmo
Summary: The type and composition of surrogate biological fluids, as well as the liquid to solid ratio, significantly affect the bioaccessibility of metal(loid)s in ambient particulate matter. Adding glycine to Gamble's solution can greatly increase bioaccessibility, while ALF fluid generally exhibits the highest bioaccessibility at a liquid to solid ratio of 5000. The bioaccessibility of metal(loid)s in Gamble's fluid increases logarithmically with increasing liquid to solid ratio, while it remains constant in ALF and gastric fluid, indicating different mechanisms of solubility and availability control.
Article
Environmental Sciences
Mantuo Huang, Yuqi Zeng, Kesong Luo, Bingyan Lan, Jiwen Luo, Lixuan Zeng, Yuan Kang
Summary: Several studies have evaluated the inhalation exposure of phthalate esters (PAEs) in PM2.5, but have not considered inhalation bioaccessibility and lung penetration of PAEs in risk assessment. This study investigated the inhalation bioaccessibility of PAEs in indoor PM2.5 samples using simulated lung fluids, and tested the lung cell permeation and metabolism of selected PAEs using a lung cell model. The results showed that the inhalation bioavailability of PAEs varied depending on the health condition and the presence of inflammation.
ENVIRONMENTAL POLLUTION
(2023)
Article
Construction & Building Technology
Anna-Sofia Preece, Huan Shu, Malin Knutz, Annette M. Krais, Gabriel Beko, Carl-Gustaf Bornehag
Summary: Phthalates are widely used in consumer products and exposure can lead to adverse health effects, particularly with early-life exposure. This study found that intake from residential dust and air contributes significantly to total daily intakes of certain phthalates, while reducing low molecular weight phthalates in the indoor environment can help reduce intake among pregnant women.
Article
Environmental Sciences
Tatiya Wannomai, Hidenori Matsukami, Natsuyo Uchida, Fumitake Takahashi, Le Huu Tuyen, Pham Hung Viet, Shin Takahashi, Tatsuya Kunisue, Go Suzuki
Summary: This study assessed the inhalation exposure to flame retardants in indoor dust by workers at e-waste-dismantling workshops in northern Vietnam. The results showed that the bioaccessible concentrations of flame retardants were significantly lower than their mass concentrations.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Engineering, Environmental
Yumeng Shi, Leicheng Zhao, Hongkai Zhu, Zhipeng Cheng, Haining Luo, Hongwen Sun
Summary: The occupational exposure of e-waste dismantlers to plasticizers, especially non-phthalate (NPAE) plasticizers, is not well understood. This study monitored the concentrations of 11 phthalates (PAEs) and 16 NPAEs in dust and hand wipe samples from e-waste workplaces and ordinary homes in Central China. The results showed that the concentrations of plasticizers in dust from e-waste workplaces were significantly lower than that from ordinary homes, while there was a similar but not significant trend in hand wipes. PAEs were still the dominant plasticizers, with concentrations on average 5.46 and 3.58-fold higher than NPAEs.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Pharmacology & Pharmacy
Lucas Panneel, Paulien Cleys, Camille Breugelmans, Christina Christia, Govindan Malarvannan, Giulia Poma, Philippe G. Jorens, Antonius Mulder, Adrian Covaci
Summary: We investigated the concentrations of DEHP and alternative plasticizers (APs) to which premature neonates are exposed during parenteral nutrition (PN) therapy. Our results showed that DEHP and several APs are present in medical devices used for neonatal PN administration, with higher concentrations found in lipid emulsions. Premature neonates receiving PN therapy were estimated to be exposed to 13.9 μg/kg/d of DEHP and 95.7 μg/kg/d of ATBC, below their respective reference doses.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Environmental Sciences
Somayeh Abdi, Soheil Sobhanardakani, Bahareh Lorestani, Mehrdad Cheraghi, Homayon Ahmad Panahi
Summary: The study evaluated the carcinogenic and non-carcinogenic risks of phthalate esters in dust from 21 schools in Tehran, finding dust ingestion as the main exposure pathway. Results showed concentrations of phthalate esters in samples were below the US EPA threshold, but still pose risks to human safety.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Environmental Sciences
Xu Li, Wenping Zhang, Jiapei Lv, Wenxiu Liu, Shanwei Sun, Changsheng Guo, Jian Xu
Summary: Phthalates were widely detected in indoor dusts in China, with significant differences in concentration distribution due to economic development and PAE product usage. Potential sources of PAEs in indoor dusts included cosmetics, plasticizers, and household building materials. Noncancer risks were posed by DBP, DEHP, DnOP, and BBzP exposure, while carcinogenic risks from BBzP and DEHP were negligible.
ENVIRONMENTAL SCIENCES EUROPE
(2021)
Article
Construction & Building Technology
Luyao Zhang, Garthika Navaranjan, Tim K. Takaro, Sarah Bernstein, Liisa Jantunen, Wendy Lou, Piush J. Mandhane, Theo J. Moraes, James A. Scott, Elinor Simons, Stuart E. Turvey, Padmaja Subbarao, Jeffrey R. Brook
Summary: This study found that DEHP concentrations in house dust were higher in lower-income families and in homes with vinyl flooring in the kitchen and bathroom. The presence of vinyl furniture and mold were also associated with higher DEHP concentrations, while the use of mattress covers reduced concentration. DEHP persisted in house dust over multiple months, contributed to infant internal exposure, and was associated with specific housing characteristics. These findings can guide the public in choosing building materials and products, as well as inform future policies aimed at reducing health risks for children in indoor environments.
Article
Chemistry, Physical
Natalia Barteczko, Justyna Wieclawik, Anna Tracz, Ewa Pankalla, Karol Erfurt, Piotr Latos, Slawomir Boncel, Karolina Matuszek, Anna Chrobok
Summary: A synthetic method for alternative plasticizers (dialkyl succinates and adipates) was presented via esterification reaction using ionic liquids as acidic catalyst and solvent, forming a two-phase liquid-liquid system. High yields and selectivities of the products were achieved under mild reaction conditions, with the catalyst being reusable. The method is competitive due to its simplicity in product isolation, high yield, and purity of the resulting esters, making it sustainable and promising for industrial applications.
Article
Engineering, Environmental
Bo Yuan, Joo Hui Tay, Juan Antonio Padilla-Sanchez, Eleni Papadopoulou, Line Smastuen Haug, Cynthia A. de Wit
Summary: Different chain lengths of chlorinated paraffins were found in indoor air and dust collected from living rooms of adults in a Norwegian cohort. Relatively volatile chlorinated paraffins showed a greater tendency to transfer from settled dust to indoor air, with inhalation being the predominant exposure pathway.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Environmental Sciences
Rahat Riaz, Cynthia A. de Wit, Riffat Naseem Malik
Summary: The study found differences in concentrations and patterns of residual organic pollutants in fish from the Lesser Himalayan Region, indicating the influence of lake types and human activities. Stable isotopes and nutritional characteristics were identified as important factors in explaining the variability of these compounds.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Construction & Building Technology
Sarka Langer, Cynthia A. de Wit, Georgios Giovanoulis, Jenny Faldt, Linnea Karlson
Summary: Young children spend a significant amount of their waking time in preschools, so it is crucial to reduce the presence of hazardous SVOCs in their indoor environment. Using approved building materials for renovation can effectively lower SVOC concentrations in preschools.
Article
Environmental Sciences
Veronica van der Schyff, Lenka Suchankova, Katerina Kademoglou, Lisa Melymuk, Jana Klanova
Summary: The personal care product industry is a multi-billion-dollar industry worldwide. While some products are marketed as green or natural, there is no significant difference in the concentrations of harmful compounds between green and conventional products. However, the cumulative intake of harmful compounds is an order of magnitude higher for individuals using conventional products compared to those using green products exclusively.
Article
Engineering, Environmental
Linn Persson, Bethanie M. Carney Almroth, Christopher D. Collins, Sarah Cornell, Cynthia A. de Wit, Miriam L. Diamond, Peter Fantke, Martin Hassellov, Matthew MacLeod, Morten W. Ryberg, Peter Sogaard Jorgensen, Patricia Villarrubia-Gomez, Zhanyun Wang, Michael Zwicky Hauschild
Summary: This article suggests that the safe operating space of the planetary boundary for novel entities is exceeded due to the increasing production and releases exceeding the global capacity for assessment and monitoring. Plastic pollution is highlighted as a major concern. The article presents an impact pathway from the production of novel entities to their impacts on Earth system processes and proposes several criteria for control variables. Urgent action is recommended to reduce the harm associated with exceeding the boundary by reducing the production and releases of novel entities.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Biochemical Research Methods
T. Liapikos, C. Zisi, D. Kodra, K. Kademoglou, D. Diamantidou, O. Begou, A. Pappa-Louisi, G. Theodoridis
Summary: This study developed QSRR models based on machine learning for the prediction of retention time in metabolomics. Different regression algorithms were tested and compared using experimental and publicly available chromatographic data. The results showed that the selected regression algorithms were able to effectively handle collinearity and there was no significant difference in the performance of the predictive models among different dataset configurations.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2022)
Review
Chemistry, Analytical
Cynthia A. de Wit, Katrin Vorkamp, Derek Muir
Summary: Persistent organic pollutants (POPs) have accumulated in polar environments due to long-range transport. Climate change has been identified as a factor influencing POP levels and trends, and recent studies have found correlations between climate indices and POP temporal trends. Temperature, precipitation, and sea-ice have also been recognized as important climate parameters affecting POP levels. However, the complexity of physical, chemical, and biological processes requires greater interdisciplinary scientific exchange and collaboration.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2022)
Editorial Material
Engineering, Environmental
Linn Persson, Bethanie M. Carney Almroth, Christopher D. Collins, Sarah Cornell, Cynthia A. de Wit, Miriam L. Diamond, Peter Fantke, Martin Hassellov, Matthew MacLeod, Morten W. Ryberg, Peter Sogaard Jorgensen, Patricia Villarrubia-Gomez, Zhanyun Wang, Michael Zwicky Hauschild
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Engineering, Environmental
Bo Yuan, Cynthia A. de Wit
Summary: A study found relatively high concentrations of chlorinated paraffins (CPs) in moose from Grimso'', Sweden compared to other wildlife in Scandinavia. The study examined the temporal trends of CP concentrations in moose calves over the past 40 years. The results showed increasing CP concentrations from 1982 to the 1990s, high levels in 1993 and 2008, and decreasing concentrations after 2012. Male moose had exponentially increasing CP levels with age, while females had exponentially decreasing CP levels. The accumulation of CPs in moose suggests additional stress on males of this long-lived terrestrial mammal.
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
(2022)
Article
Environmental Sciences
Erica Selin, Mimmi Wann, Kettil Svensson, Erik Gravenfors, Georgios Giovanoulis, Agneta Oskarsson, Johan Lundqvist
Summary: This study conducted an effect-based evaluation of non-polar extracts of food contact articles made of paper and board. The results showed that these extracts contain compounds that can activate molecular initiating events in toxicity pathways related to human health, including endocrine-disruptive activities, oxidative stress, and genotoxicity. The use of effect-based methods proved to be valuable in detecting potentially hazardous effects of known and unknown chemicals in food package articles.
ENVIRONMENTAL SCIENCES EUROPE
(2022)
Article
Engineering, Environmental
Bo Yuan, Line Smastuen Haug, Joo Hui Tay, Juan Antonio Padilla-Sanchez, Eleni Papadopoulou, Cynthia A. de Wit
Summary: This study quantified the internal and external exposure of chlorinated paraffins (CPs) in a defined human cohort, finding that dietary intake contributed the most to body burden of CPs. Different chain lengths of CPs showed different exposure pathways and contribution rates, highlighting the need for enhanced biomonitoring and exposure data collection for CPs in regions beyond China and European countries.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Engineering, Environmental
Kyra M. Spaan, Fredric Seilitz, Merle M. Plassmann, Cynthia A. de Wit, Jonathan P. Benskin
Summary: Fluorine mass balance studies in municipal wastewater treatment plant (WWTP) sludge showed that conventional per- and polyfluoroalkyl substances (PFAS) account for only a small fraction (approximately 2%) of the extractable organic fluorine (EOF). The remaining EOF, which includes fluorine-containing pharmaceuticals and pesticides, was identified using high resolution mass spectrometry-based suspect screening. The presence of various pharmaceutical substances, pesticides, and conventional PFAS was confirmed, expanding the known EOF percentage from 2% to 27%. These findings highlight the importance of considering unconventional and non-PFAS organofluorine substances in addition to conventional PFAS when assessing the organofluorine mass balance in WWTP sludge.
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
(2023)
Review
Chemistry, Analytical
Katrin Vorkamp, Pernilla Carlsson, Simonetta Corsolini, Cynthia A. de Wit, Rune Dietz, Matthew O. Gribble, Magali Houde, Vrinda Kalia, Robert J. Letcher, Adam Morris, Frank F. Riget, Heli Routti, Derek C. G. Muir
Summary: Time series of contaminants in the Arctic are important for detecting emerging issues and monitoring the effectiveness of chemicals regulation. Climate change could influence these time trends, but the mechanisms are not well understood. Biological data indicate changes in diet and trophic level of some species, while physical climate parameters show correlations with POP temporal trends.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2022)