期刊
ACS BIOMATERIALS SCIENCE & ENGINEERING
卷 4, 期 2, 页码 719-727出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsbiomaterials.7b00916
关键词
porous scaffold; Voronoi-Tessellation; selective laser melting; stress shielding; elastic modulus; gradient pore structure
资金
- Key Research and Development Plan of Jiangsu Province [BE2016010-3]
- Science and Technology Support Program (The Industrial Part)
- Jiangsu Provincial Department of Science and Technology of China [BE2014009-1]
- Science and Technology Supporting Plan (The Industrial Part) of Zhangjiagang [ZKG1615]
- Science and Technology Supporting Plan (Social Development Part) of Zhangjiagang [ZKS1606]
- Nation Nature Science Fund of China [51475238]
Adjustment of the mechanical properties (apparent elastic modulus and compressive strength) in porous scaffolds is important for artificial implants and bone tissue engineering. In this study, a top-down design method based on Voronoi-Tessellation was proposed. This method was successful in obtaining the porous structures with specified and functionally graded porosity. The porous specimens were prepared by selective laser melting technology. Quasi static compressive tests were conducted as well. The experiment results revealed that the mechanical properties were affected by both porosity and irregularity. The irregularity coefficient proposed in this study can achieve good accommodation and balance of irregularity and controllability. The method proposed in this study provides an efficient approach for the bionic design and topological optimization of scaffolds.
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