Article
Cell Biology
Li Zhang, Qingde Zhou, Min Chen, Xuanxin Yang, Chao Lu, Wenzhe Sun, Qi Hui, Xiaojie Wang
Summary: Research findings suggest that rh-aFGF(135) exhibits a strong hypoglycemic effect in type 2 diabetic ZDF rats, improving hyperglycemia and insulin resistance without adverse effects of hypoglycemia. Additionally, high dosage of rh-aFGF(135) also has the potential to remodel adipose tissue effectively.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Soheila Rezaei, Rana Imani
Summary: This study introduces a promising wound dressing based on a combination of egg white and Carbomer-940. The hydrofilm dressing provides high absorbency and bioactivity, making it suitable for managing exudate-secreting wounds, such as diabetic wounds.
MACROMOLECULAR BIOSCIENCE
(2023)
Article
Pharmacology & Pharmacy
Agnieszka Kostrzebska, Adrianna Zlocinska, Witold Musial
Summary: The study found that the TC concentration decreased from 9.37 µg/mL to 4.41 µg/mL within approximately two months when stored at 23 degrees C under photoprotection. However, lowering the storage temperature did not improve the final level of TC. Additionally, the TC level in aqueous solution decreased drastically to approximately 1 µg/mL in the presence of AMPD.
Article
Biochemistry & Molecular Biology
Agnieszka Kostrzebska, Karolina Paczek, Angelika Weselak, Witold Musial
Summary: Due to its high instability and rapid degradation under adverse conditions, tetracycline hydrochloride (TC) poses challenges in developing a stable formulation for acne treatment. The aim of the study was to propose a hydrogel formulation that ensures TC stability and activities against the components of sebum. Formulations with varying proportions of anionic polymer and alcoholamine, containing different polymers, were developed and evaluated for TC stability and activity against sebum components.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Physical
Zdenek Rafaj, Jozef Krutel, Vaclav Nehasil
Summary: Rhodium (Rh) is predominantly used in the automotive industry for three-way catalysis (TWC), with improved efficiency achieved by adding CeO2-active support for oxygen storage capacity. In this study, the CO oxidation mechanism of Rh nanoparticles on CeO2(111) and CeO2(110) was investigated, revealing higher performance on Rh/CeO2(110) due to weaker CO-Rh bond and increased oxygen exchange activity.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Inorganic & Nuclear
Yipeng Zang, Yueyue Wang, Ruili Sang, Li Xu
Summary: The redox reaction of monovalent Rh-2(CO)(4)Cl(2) and Bi-n(n-) (n = 2, 3) in ethylenediamine solution led to the formation of a decabismuthide-hexarhodium dianion [Rh@Bi-10(RhCO)(5)](2-) (1a), where a novel Bi10-bowl was constructed from oxidized 2Bi(3)/2Bi(2) open triangles/dimers. The structure of 1a was stabilized by strong bonding to a reduced Rh@(RhCO)(5) square pyramid. Weak interactions between two 1a dianions formed a dimer [Rh@Bi-10(RhCO)(5)](2)(4-) (1). The structure and bonding of the novel polybismuthide heteroanion 1 are discussed.
DALTON TRANSACTIONS
(2023)
Article
Multidisciplinary Sciences
Insoo Ro, Ji Qi, Seungyeon Lee, Mingjie Xu, Xingxu Yan, Zhenhua Xie, Gregory Zakem, Austin Morales, Jingguang G. Chen, Xiaoqing Pan, Dionisios G. Vlachos, Stavros Caratzoulas, Phillip Christopher
Summary: This study investigates the catalytic mechanism of ethylene hydroformylation using supported, atomically dispersed Rh-WOx pair sites. Through Rh-assisted WOx reduction, transfer of ethylene from WOx to Rh, and H2 dissociation at the Rh-WOx interface, the pair sites exhibit high activity and selectivity, demonstrating the potential of oxide-supported pair sites in industrial reactions performed with homogeneous catalysts.
Article
Chemistry, Multidisciplinary
Hang-Fei Tu, Alienor Jeandin, Marcos G. Suero
Summary: In this study, a catalytic one-step synthesis of cyclopropenium cations using readily available alkynes and hypervalent iodine reagents as carbyne sources is reported. A novel Rh-carbynoid catalytically generates monovalent cationic carbynes (:C+-R), which are then transferred to alkynes via an oxidative [2+1] cycloaddition, resulting in a new type of ester-substituted CPC. This method allows for regioselective attack of various carbon and heteroatomic nucleophiles, providing a new platform for the synthesis of valuable cyclopropenes that are difficult or impossible to make by current methodologies.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Review
Engineering, Biomedical
Lei Zhang, Liang Yao, Feng Zhao, Alice Yu, Yueru Zhou, Qingmei Wen, Jun Wang, Tao Zheng, Pu Chen
Summary: Anthocyanin is a natural polyphenol with excellent antioxidant, anticancer, antiaging, antimicrobial, and anti-inflammatory properties. However, its stability and bioavailability are limited in extreme environments. Encapsulating anthocyanin with biomaterials or combining it with proteins and peptides can effectively stabilize it. This review focuses on recent progress, strategies, and perspectives on protein and peptide stabilization of anthocyanin for functionalization and delivery, including formulation technologies, stability enhancement, cellular uptake, bioavailabilities, and biological activities.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Food Science & Technology
Yu Fu, Wanning Liu, Olugbenga P. Soladoye
Summary: Flavonoids, a group of phytochemicals with diverse bioactivities, are widely distributed in plant-based foods. Food processing can have both positive and negative impacts on the stability and bioactivity of flavonoid compounds. Different processing methods may affect flavonoid content and antioxidant activities.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Inorganic & Nuclear
Yishuang Xu, Gang Wang, Ping Qian, Yanjing Su
Summary: A new angular-dependent potential (ADP) was obtained for the Ni-Rh system by fitting experimental and first principle data, and its effectiveness was tested. The segregation characteristics and thermal stability of Ni-Rh nanoparticles were studied using Monte Carlo and molecular dynamics, revealing that the chemical ordering pattern of Ni1-xRhx nanoparticles is determined by the competition of different energy terms. The results also explain the reason behind the improvement in coking resistance and sintering-resistance ability of Ni catalyst with the doping of a small amount of Rh.
JOURNAL OF SOLID STATE CHEMISTRY
(2022)
Article
Food Science & Technology
Juan Pablo Carreon-Hidalgo, Diana Carolina Franco-Vasquez, Dario R. Gomez-Linton, Laura J. Perez-Flores
Summary: Betalains are plant pigments primarily used as food dyes, but they are prone to instability due to environmental factors. Various extraction methods and stabilization techniques have been developed to increase shelf life, as well as diverse biological properties that make betalains suitable for applications in various industries such as food, cosmetics, textiles, and solar cells.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Food Science & Technology
Na Li, Chuanju Wang, Baijian Feng, Yongguang Bi, Fansheng Kong, Zhong Wang, Shaofan Tan
Summary: Nanoemulsion encapsulation technology can improve the stability and biological activity of tea polyphenols, expanding their application in the food industry.
Article
Chemistry, Multidisciplinary
Johannes Morstein, Alice Capecchi, Konstantin Hinnah, ByungUk Park, Jerome Petit-Jacques, Reid C. Van Lehn, Jean-Louis Reymond, Dirk Trauner
Summary: Most bioactive molecules need to cross or be distributed into biological membranes, and natural products often have lipid modifications to facilitate molecule-membrane interactions. Lipidated natural products primarily contain saturated medium-chain lipids, and lipid conjugation can significantly modulate the permeability, cellular retention, subcellular localization, and bioactivity of small molecules.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Biochemistry & Molecular Biology
Christian M. Sanchez-Lopez, Mari Cruz Manzaneque-Lopez, Pedro Perez-Bermudez, Carla Soler, Antonio Marcilla
Summary: In this study, pomegranate juice extracellular vesicles (PgEVs) were isolated for the first time using size exclusion chromatography (SEC). Characterization of PgEVs by nanoparticle tracking analysis (NTA) and transmission electron microscopy (TEM) revealed their concentration, size, and morphology, which were comparable to plant-derived EVs. Proteomic analysis identified 131 proteins in PgEVs, including those related to the biogenesis and transport of EVs. PgEVs demonstrated anti-inflammatory, antioxidant, and wound-healing effects in in vitro cultures of THP-1 and Caco-2 cell lines.
Article
Biochemical Research Methods
Xuanxin Yang, Qi Hui, Bingjie Yu, Zhen Huang, PeiPei Zhou, Panfeng Wang, Zhitao Wang, Shucai Pang, Jinghang Li, Hanshi Wang, Li Lin, Xiaokun Li, Xiaojie Wang
BIOCONJUGATE CHEMISTRY
(2018)
Article
Materials Science, Biomaterials
Qi Hui, Li Zhang, Xuanxin Yang, Bingjie Yu, Zhen Huang, Shucai Pang, Qingde Zhou, Rongshuai Yang, Wenqing Li, Lufeng Hu, Xiaokun Li, Gaozhong Cao, Xiaojie Wang
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2018)
Article
Biotechnology & Applied Microbiology
Qi Hui, Zhen Huang, Shucai Pang, Xuanxin Yang, Jinghang Li, Bingjie Yu, Lu Tang, Xiaokun Li, Xiaojie Wang
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2019)
Article
Ophthalmology
JianQiu Cai, Qingde Zhou, Zhitao Wang, Ruide Guo, Rongshuai Yang, Xuanxin Yang, Wenqing Li, Naveed Ahmad, Qi Chen, Qi Hui, Xiaojie Wang
Article
Endocrinology & Metabolism
Xuanxin Yang, Rongshuai Yang, Min Chen, Qingde Zhou, Yingying Zheng, Chao Lu, Jianing Bi, Wenzhe Sun, Tongzhou Huang, Lijia Li, Jianxiang Gong, Xiaokun Li, Qi Hui, Xiaojie Wang
BMJ OPEN DIABETES RESEARCH & CARE
(2020)
Article
Materials Science, Biomaterials
Aipeng Deng, Yang Yang, Shimei Du, Xuanxin Yang, Shucai Pang, Xiaojie Wang, Shulin Yang
Summary: Thermoresponsive hydrogels formed by conjugating recombinant human collagen-peptide (RHC) with chitosan exhibit lower gelation temperature and superior mechanical strength, showing good biocompatibility with cells and promoting cell infiltration, vessel formation, and wound healing. Overall, the use of RHC-chitosan hydrogels is a promising and effective therapeutic approach for burn wound treatment.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Cell Biology
Li Zhang, Qingde Zhou, Min Chen, Xuanxin Yang, Chao Lu, Wenzhe Sun, Qi Hui, Xiaojie Wang
Summary: Research findings suggest that rh-aFGF(135) exhibits a strong hypoglycemic effect in type 2 diabetic ZDF rats, improving hyperglycemia and insulin resistance without adverse effects of hypoglycemia. Additionally, high dosage of rh-aFGF(135) also has the potential to remodel adipose tissue effectively.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Materials Science, Biomaterials
Hao Pan, Changcan Shi, Rongshuai Yang, Guanghui Xi, Chao Lu, Xuanxin Yang, Jie Chen, Xiaojie Wang, Lei Chen, Jingye Pan
Summary: KGF-2@PHMs enhance the bioavailability of KGF-2, reduce inflammation, and accelerate wound healing process through controlled release, potentially serving as an alternative strategy for wound healing in future clinical applications.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
