Icariin Ameliorate Thiram-Induced Tibial Dyschondroplasia via Regulation of WNT4 and VEGF Expression in Broiler Chickens

Effect of tetramethylpyrazine on tibial dyschondroplasia incidence, tibial angiogenesis, performance and characteristics via HIF-1α/VEGF signaling pathway in chickens

(2018) Khalid Mehmood et al.   Scientific Reports

Inhibition of estrogen related receptor α attenuates vascular smooth muscle cell proliferation and migration by regulating RhoA/p27 Kip1 and β-Catenin/Wnt4 signaling pathway

(2017) Qunyi Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Icariin protects against thioacetamide-induced liver fibrosis in rats: Implication of anti-angiogenic and anti-autophagic properties

(2017) Mardi M. Algandaby et al.   Pharmacological Reports

Hsp90 inhibitor celastrol reinstates growth plate angiogenesis in thiram-induced tibial dyschondroplasia

(2016) Fazul Nabi et al.   AVIAN PATHOLOGY

Icariin Attenuates OGD/R-Induced Autophagy via Bcl-2-Dependent Cross Talk between Apoptosis and Autophagy in PC12 Cells

(2016) Zhen-tao Mo et al.   Evidence-based Complementary and Alternative Medicine

Icariin alters the expression of glucocorticoid receptor, FKBP5 and SGK1 in rat brains following exposure to chronic mild stress

(2016) KAI WEI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Flavonoid Compound Icariin Activates Hypoxia Inducible Factor-1α in Chondrocytes and Promotes Articular Cartilage Repair

(2016) Pengzhen Wang et al.   PLoS One

The Cardioprotective Effect of Icariin on Ischemia-Reperfusion Injury in Isolated Rat Heart: Potential Involvement of the PI3K-Akt Signaling Pathway

(2015) Zunping Ke et al.   Cardiovascular Therapeutics

Effects of icariin on the expression of ER, VEGF, and KDR in the endometrial cells of thin endometrium

(2015) A.W. Le et al.   GENETICS AND MOLECULAR RESEARCH

Pharmacological effects and pharmacokinetic properties of icariin, the major bioactive component in Herba Epimedii

(2015) Chenrui Li et al.   LIFE SCIENCES

Icariin regulates PRMT/ADMA/DDAH pathway to improve endothelial function

(2015) Hong-Bo Xiao et al.   Pharmacological Reports

Differential expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in avian tibial dyschondroplasia

(2014) Muhammad Shahzad et al.   AVIAN PATHOLOGY

Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κB

(2014) Bo Yu et al.   NATURE MEDICINE

Icariin promotes directed chondrogenic differentiation of bone marrow mesenchymal stem cells but not hypertrophy in vitro

(2014) ZHI CONG WANG et al.   Experimental and Therapeutic Medicine

Screening of differentially expressed genes in the growth plate of broiler chickens with Tibial Dyschondroplasia by microarray analysis

(2013) Wen-xia Tian et al.   BMC GENOMICS

The role of estrogen receptor α in the regulation of bone and growth plate cartilage

(2013) A. E. Börjesson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Icariin Augments Bone Formation and Reverses the Phenotypes of Osteoprotegerin-Deficient Mice through the Activation of Wnt/β-Catenin-BMP Signaling

(2013) Xiao-Feng Li et al.   Evidence-based Complementary and Alternative Medicine

Plant polyphenols in the treatment of age-associated diseases: Revealing the pleiotropic effects of icariin by network analysis

(2013) Jan Kevin Schluesener et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Expression and identification of recombinant chicken vascular endothelial growth factor in Pichia pastoris and its role in the pathogenesis of tibial dyschondroplasia

(2013) J.- P. Zhang et al.   POULTRY SCIENCE

The effect of TNFα secreted from macrophages activated by titanium particles on osteogenic activity regulated by WNT/BMP signaling in osteoprogenitor cells

(2012) Sang-Soo Lee et al.   BIOMATERIALS

Icariin: a potential promoting compound for cartilage tissue engineering

(2012) D. Li et al.   OSTEOARTHRITIS AND CARTILAGE

Icariin Promotes Extracellular Matrix Synthesis and Gene Expression of Chondrocytes In Vitro

(2012) Lei Zhang et al.   PHYTOTHERAPY RESEARCH

The effect of inhibition of heat-shock proteins on thiram-induced tibial dyschondroplasia

(2012) O. Genin et al.   POULTRY SCIENCE

Hsp90 and angiogenesis in bone disorders—lessons from the avian growth plate

(2011) Ayelet Herzog et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Expression of Genes Encoding Extracellular Matrix Macromolecules and Metalloproteinases in Avian Tibial Dyschondroplasia

(2011) I. Velada et al.   JOURNAL OF COMPARATIVE PATHOLOGY

The effects of broiler chicken growth rate on valgus, varus, and tibial dyschondroplasia

(2011) M. Y. Shim et al.   POULTRY SCIENCE

The structural biochemistry of the superoxide dismutases

(2009) J.J.P. Perry et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Aggrecan modulation of growth plate morphogenesis

(2009) Miriam S. Domowicz et al.   DEVELOPMENTAL BIOLOGY

Expression of matrix metalloproteinases during impairment and recovery of the avian growth plate1

(2009) H. Dan et al.   JOURNAL OF ANIMAL SCIENCE

Antiosteoporotic activity of icariin in ovariectomized rats

(2009) H. Nian et al.   PHYTOMEDICINE

Icariin: A Potential Osteoinductive Compound for Bone Tissue Engineering

(2009) Jiyuan Zhao et al.   TISSUE ENGINEERING PART A

Effects of high dietary vitamin A supplementation on tibial dyschondroplasia, skin pigmentation and growth performance in avian broilers

(2008) Jiakui Li et al.   RESEARCH IN VETERINARY SCIENCE