Apigenin and Luteolin Attenuate the Breaching of MDA-MB231 Breast Cancer Spheroids Through the Lymph Endothelial Barrier in Vitro

Fenofibrate inhibits tumour intravasation by several independent mechanisms in a 3-dimensional co-culture model

(2017) Chi Huu Nguyen et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Apigenin inhibits proliferation and invasion, and induces apoptosis and cell cycle arrest in human melanoma cells

(2017) Guangming Zhao et al.   ONCOLOGY REPORTS

Dietary Flavonoids Luteolin and Quercetin Suppressed Cancer Stem Cell Properties and Metastatic Potential of Isolated Prostate Cancer Cells

(2016) PEI-HSUN TSAI et al.   ANTICANCER RESEARCH

Cancer cell-derived 12(S)-HETE signals via 12-HETE receptor, RHO, ROCK and MLC2 to induce lymph endothelial barrier breaching

(2016) Chi Huu Nguyen et al.   BRITISH JOURNAL OF CANCER

12(S)-HETE increases intracellular Ca2+ in lymph-endothelial cells disrupting their barrier function in vitro; stabilization by clinical drugs impairing calcium supply

(2016) Chi Huu Nguyen et al.   CANCER LETTERS

Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca2+ signalling

(2016) Serena Stadler et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

AHR/CYP1A1 interplay triggers lymphatic barrier breaching in breast cancer spheroids by inducing 12(S)-HETE synthesis

(2016) Chi Huu Nguyen et al.   HUMAN MOLECULAR GENETICS

Luteolin suppresses the metastasis of triple-negative breast cancer by reversing epithelial-to-mesenchymal transition via downregulation of β-catenin expression

(2016) Dan Lin et al.   ONCOLOGY REPORTS

Apigenin inhibits NF-κB and Snail signaling, EMT and metastasis in human hepatocellular carcinoma

(2016) Yuan Qin et al.   Oncotarget

NF-κB contributes to MMP1 expression in breast cancer spheroids causing paracrine PAR1 activation and disintegrations in the lymph endothelial barrier in vitro

(2015) Chi Huu Nguyen et al.   Oncotarget

Flavonoid Intake in European Adults (18 to 64 Years)

(2015) Anna Vogiatzoglou et al.   PLoS One

Discovery of lesser known flavones as inhibitors of NF-κB signaling in MDA-MB-231 breast cancer cells—A SAR study

(2014) K. Amrutha et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Enhanced bioavailability of apigenin via preparation of a carbon nanopowder solid dispersion

(2014) Shumin Ding et al.   International Journal of Nanomedicine

Tumor MMP-1 Activates Endothelial PAR1 to Facilitate Vascular Intravasation and Metastatic Dissemination

(2013) A. Juncker-Jensen et al.   CANCER RESEARCH

Minireview on Achillea millefolium Linn

(2013) Muhammad Akram   JOURNAL OF MEMBRANE BIOLOGY

Flavonoids, Flavonoid Subclasses and Breast Cancer Risk: A Meta-Analysis of Epidemiologic Studies

(2013) Chang Hui et al.   PLoS One

Distinct mechanisms of relaxation to bioactive components from chamomile species in porcine isolated blood vessels

(2013) R.E. Roberts et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Dietary flavonoid intake and risk of stomach and colorectal cancer

(2013) Hae Dong Woo   WORLD JOURNAL OF GASTROENTEROLOGY

Effects of the natural flavone trimethylapigenin on cardiac potassium currents

(2012) Yi Liu et al.   BIOCHEMICAL PHARMACOLOGY

Bay11-7082 inhibits the disintegration of the lymphendothelial barrier triggered by MCF-7 breast cancer spheroids; the role of ICAM-1 and adhesion

(2012) K Viola et al.   BRITISH JOURNAL OF CANCER

Effects of Scrophularia extracts on tumor cell proliferation, death and intravasation through lymphoendothelial cell barriers

(2012) Ali �zmen   INTERNATIONAL JOURNAL OF ONCOLOGY

NF-κB mediates the 12(S)-HETE-induced endothelial to mesenchymal transition of lymphendothelial cells during the intravasation of breast carcinoma cells

(2011) C Vonach et al.   BRITISH JOURNAL OF CANCER

Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse

(2011) Dontscho Kerjaschki et al.   JOURNAL OF CLINICAL INVESTIGATION

Acacetin causes a frequency- and use-dependent blockade of hKv1.5 channels by binding to the S6 domain

(2011) Hui-Jun Wu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Context-Specific Regulation of NF-κB Target Gene Expression by EZH2 in Breast Cancers

(2011) Shuet Theng Lee et al.   MOLECULAR CELL

Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells

(2010) Samir Attoub et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mechanical stretch decreases FAK phosphorylation and reduces cell migration through loss of JIP3-induced JNK phosphorylation in airway epithelial cells

(2009) Leena P. Desai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Targeting focal adhesion kinase signaling in tumor growth and metastasis

(2009) Joerg Schwock et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells

(2009) Vasilis P. Androutsopoulos et al.   TOXICOLOGY

Scutellarin induced Ca2+ release and blocked KCl-induced Ca2+ influx in smooth muscle cells isolated from rat thoracic artery

(2008) Bang-Hao Zhu et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Formation of Kv2.1-FAK complex as a mechanism of FAK activation, cell polarization and enhanced motility

(2008) Jian-Feng Wei et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Intestinal Absorption of Luteolin from Peanut Hull Extract Is More Efficient than That from Individual Pure Luteolin

(2007) Ping Zhou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY