PRMT5 promotes cell proliferation by inhibiting BTG2 expression via the ERK signaling pathway in hepatocellular carcinoma

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Prostate-derived ets factor represses tumorigenesis and modulates epithelial-to-mesenchymal transition in bladder carcinoma cells

(2016) Ke-Hung Tsui et al.   CANCER LETTERS

Protein arginine methyltransferase 5 is associated with malignant phenotype and peritoneal metastasis in gastric cancer

(2016) Mitsuro Kanda et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression

(2016) H Chen et al.   ONCOGENE

Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth

(2016) X Deng et al.   ONCOGENE

Molecular Pathogenesis of Hepatocellular Carcinoma

(2016) Daniel Wai-Hung Ho et al.   Liver Cancer

Upregulation of B-cell translocation gene 2 by epigallocatechin-3-gallate via p38 and ERK signaling blocks cell proliferation in human oral squamous cell carcinoma cells

(2015) Jehn-Chuan Lee et al.   CANCER LETTERS

Targeting protein arginine methyltransferase 5 inhibits human hepatocellular carcinoma growth via the downregulation of beta-catenin

(2015) Baolai Zhang et al.   Journal of Translational Medicine

SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes

(2015) Ken Tajima et al.   Nature Communications

Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis

(2013) Maddalena Frau et al.   JOURNAL OF HEPATOLOGY

Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade

(2012) Tong-You W. Wei et al.   CANCER SCIENCE

Overexpression of Aurora-A Enhances Invasion and Matrix Metalloproteinase-2 Expression in Esophageal Squamous Cell Carcinoma Cells

(2012) X. Wang et al.   MOLECULAR CANCER RESEARCH

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

Protein Arginine Methyltransferase 5 Regulates ERK1/2 Signal Transduction Amplitude and Cell Fate Through CRAF

(2011) P. Andreu-Perez et al.   Science Signaling

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The expression of myogenic microRNAs indirectly requires protein arginine methyltransferase (Prmt)5 but directly requires Prmt4

(2010) C. Mallappa et al.   NUCLEIC ACIDS RESEARCH

Melatonin inhibits human fibroblast-like synoviocyte proliferation via extracellular signal-regulated protein kinase/P21CIP1/P27KIP1pathways

(2009) Seong-Su Nah et al.   JOURNAL OF PINEAL RESEARCH

Distinct Protein Arginine Methyltransferases Promote ATP-Dependent Chromatin Remodeling Function at Different Stages of Skeletal Muscle Differentiation

(2009) C. S. Dacwag et al.   MOLECULAR AND CELLULAR BIOLOGY

PRMT5 is required for cell-cycle progression and p53 tumor suppressor function

(2009) A. Scoumanne et al.   NUCLEIC ACIDS RESEARCH

Ski co-repressor complexes maintain the basal repressed state of the TGF-β target gene,SMAD7, via HDAC3 and PRMT5

(2008) Takanori Tabata et al.   GENES TO CELLS

Molecular mechanisms of hepatocellular carcinoma

(2008) Rajagopal N. Aravalli et al.   HEPATOLOGY

TIS21 negatively regulates hepatocarcinogenesis by disruption of cyclin B1-Forkhead box M1 regulation loop

(2008) Tae Jun Park et al.   HEPATOLOGY

Protein Arginine Methyltransferase 5 Suppresses the Transcription of the RB Family of Tumor Suppressors in Leukemia and Lymphoma Cells

(2008) L. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY