Diagnosis of major depressive disorder based on changes in multiple plasma neurotransmitters: a targeted metabolomics study

Altered plasma protein glycosylation in a mouse model of depression and in patients with major depression

(2018) Hirotaka Yamagata et al.   JOURNAL OF AFFECTIVE DISORDERS

Peripheral biomarkers of major depression and antidepressant treatment response: Current knowledge and future outlooks

(2018) Bharathi S. Gadad et al.   JOURNAL OF AFFECTIVE DISORDERS

Metabolomics identifies perturbations in amino acid metabolism in the prefrontal cortex of the learned helplessness rat model of depression

(2017) Xinyu Zhou et al.   NEUROSCIENCE

Identification of plasma biomarkers for distinguishing bipolar depression from major depressive disorder by iTRAQ-coupled LC–MS/MS and bioinformatics analysis

(2017) Juanjuan Ren et al.   PSYCHONEUROENDOCRINOLOGY

Assessing the presence of shared genetic architecture between Alzheimer’s disease and major depressive disorder using genome-wide association data

(2017) J Gibson et al.   Translational Psychiatry

The identification of metabolic disturbances in the prefrontal cortex of the chronic restraint stress rat model of depression

(2016) Lanxiang Liu et al.   BEHAVIOURAL BRAIN RESEARCH

Metabolomic analysis reveals metabolic disturbances in the prefrontal cortex of the lipopolysaccharide-induced mouse model of depression

(2016) Yu Wu et al.   BEHAVIOURAL BRAIN RESEARCH

Metabolite signature for diagnosing major depressive disorder in peripheral blood mononuclear cells

(2016) Peng Zheng et al.   JOURNAL OF AFFECTIVE DISORDERS

Targeted Metabolomic Pathway Analysis and Validation Revealed Glutamatergic Disorder in the Prefrontal Cortex among the Chronic Social Defeat Stress Mice Model of Depression

(2016) Wei Wang et al.   JOURNAL OF PROTEOME RESEARCH

Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis

(2016) Andrea Cipriani et al.   LANCET

Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism

(2016) P Zheng et al.   MOLECULAR PSYCHIATRY

Identification of sex-specific urinary biomarkers for major depressive disorder by combined application of NMR- and GC–MS-based metabonomics

(2016) P Zheng et al.   Translational Psychiatry

Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants

(2016) D M Rotroff et al.   Translational Psychiatry

Blood metabolite markers of neocortical amyloid-β burden: discovery and enrichment using candidate proteins

(2016) N Voyle et al.   Translational Psychiatry

Decreased sensitivity to paroxetine-induced inhibition of peripheral blood mononuclear cell growth in depressed and antidepressant treatment-resistant patients

(2016) S Rzezniczek et al.   Translational Psychiatry

Plasma Metabolites Predict Severity of Depression and Suicidal Ideation in Psychiatric Patients-A Multicenter Pilot Analysis

(2016) Daiki Setoyama et al.   PLoS One

Identification and validation of argininosuccinate synthase as a candidate urinary biomarker for major depressive disorder

(2015) Dong Wu et al.   CLINICA CHIMICA ACTA

Prefrontal cortical GABA abnormalities are associated with reduced hippocampal volume in major depressive disorder

(2015) Chadi G. Abdallah et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Quantitative Proteomic Analysis Reveals Molecular Adaptations in the Hippocampal Synaptic Active Zone of Chronic Mild Stress-Unsusceptible Rats

(2015) Jian Zhou et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

In vivo study on the neurotransmitters and their metabolites change in depressive disorder rat plasma by ultra high performance liquid chromatography coupled to tandem mass spectrometry

(2015) Longshan Zhao et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Loss of Cyclin-Dependent Kinase 5 from Parvalbumin Interneurons Leads to Hyperinhibition, Decreased Anxiety, and Memory Impairment

(2015) A. Rudenko et al.   JOURNAL OF NEUROSCIENCE

Evaluation of a specific diagnostic marker for rheumatoid arthritis based on cyclic citrullinated peptide

(2015) Min Park et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Revisiting the Serotonin Hypothesis: Implications for Major Depressive Disorders

(2015) Marc Fakhoury   MOLECULAR NEUROBIOLOGY

Polygenic dissection of major depression clinical heterogeneity

(2015) Y Milaneschi et al.   MOLECULAR PSYCHIATRY

A pilot in vivo proton magnetic resonance spectroscopy study of amino acid neurotransmitter response to ketamine treatment of major depressive disorder

(2015) M S Milak et al.   MOLECULAR PSYCHIATRY

Serotonin pathway polymorphisms and the treatment of major depressive disorder and anxiety disorders

(2015) Sarah G Helton et al.   PHARMACOGENOMICS

Biochemical markers subtyping major depressive disorder

(2015) Hiroshi Kunugi et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Altered γ-aminobutyric acid neurotransmission in major depressive disorder: a critical review of the supporting evidence and the influence of serotonergic antidepressants

(2015) Alan Pehrson et al.   Drug Design Development and Therapy

Effects of depressive symptoms and peripheral DAT methylation on neural reactivity to alcohol cues in alcoholism

(2015) C E Wiers et al.   Translational Psychiatry

Ipsilateral Hippocampal Proteomics Reveals Mitochondrial Antioxidative Stress Impairment in Cortical-Lesioned Chronic Mild Stressed Rats

(2014) J. Pan et al.   CURRENT MOLECULAR MEDICINE

ANXIETY IN MAJOR DEPRESSION AND CEREBROSPINAL FLUID FREE GAMMA-AMINOBUTYRIC ACID

(2014) J. John Mann et al.   DEPRESSION AND ANXIETY

Differential diagnosis of bipolar disorder and major depressive disorder

(2014) R.M. Hirschfeld   JOURNAL OF AFFECTIVE DISORDERS

2,4-Dihydroxypyrimidine is a potential urinary metabolite biomarker for diagnosing bipolar disorder

(2014) Xue-Jiao Xu et al.   Molecular BioSystems

GABA/glutamate co-release controls habenula output and is modified by antidepressant treatment

(2014) S. J. Shabel et al.   SCIENCE

Time-dependent metabolomic profiling of Ketamine drug action reveals hippocampal pathway alterations and biomarker candidates

(2014) K Weckmann et al.   Translational Psychiatry

Cerebrospinal fluid markers including trefoil factor 3 are associated with neurodegeneration in amyloid-positive individuals

(2014) R W Paterson et al.   Translational Psychiatry

Astrocyte Pathology in Major Depressive Disorder: Insights from Human Postmortem Brain Tissue

(2013) Grazyna Rajkowska et al.   CURRENT DRUG TARGETS

A Novel Urinary Metabolite Signature for Diagnosing Major Depressive Disorder

(2013) Peng Zheng et al.   JOURNAL OF PROTEOME RESEARCH

Interleukin-1β is associated with depressive episode in major depression but not in bipolar disorder

(2013) Rosana Mota et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Abnormal GABAergic Function and Negative Affect in Schizophrenia

(2013) Stephan F Taylor et al.   NEUROPSYCHOPHARMACOLOGY

Distinguishing between Unipolar Depression and Bipolar Depression: Current and Future Clinical and Neuroimaging Perspectives

(2012) Jorge Renner Cardoso de Almeida et al.   BIOLOGICAL PSYCHIATRY

Comparative proteomic analysis of plasma from major depressive patients: identification of proteins associated with lipid metabolism and immunoregulation

(2012) Hong-Bo Xu et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Plasma Metabonomics as a Novel Diagnostic Approach for Major Depressive Disorder

(2012) Peng Zheng et al.   JOURNAL OF PROTEOME RESEARCH

Global pattern of experienced and anticipated discrimination reported by people with major depressive disorder: a cross-sectional survey

(2012) Antonio Lasalvia et al.   LANCET

Identification and Validation of Urinary Metabolite Biomarkers for Major Depressive Disorder

(2012) Peng Zheng et al.   MOLECULAR & CELLULAR PROTEOMICS

Potential clinical utility of plasma amino acid profiling in the detection of major depressive disorder

(2012) Hong-Bo Xu et al.   PSYCHIATRY RESEARCH