Enzymes of aldoxime–nitrile pathway for organic synthesis

Nitrile Metabolizing Enzymes in Biocatalysis and Biotransformation

(2018) Tek Chand Bhalla et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

CYP79 P450 monooxygenases in gymnosperms: CYP79A118 is associated with the formation of taxiphyllin in Taxus baccata

(2017) Katrin Luck et al.   PLANT MOLECULAR BIOLOGY

Switching a nitrilase from Syechocystis sp. PCC6803 to a nitrile hydratase by rationally regulating reaction pathways

(2017) Shuiqin Jiang et al.   Catalysis Science & Technology

Biotransformation of β-keto nitriles to chiral (S)-β-amino acids using nitrilase and ω-transaminase

(2016) Sam Mathew et al.   BIOTECHNOLOGY LETTERS

Hydroxynitrile Lyase of Wild Apricot (Prunus armeniaca L.): Purification, Characterization and Application in Synthesis of Enantiopure Mandelonitrile

(2016) Mohammad Asif et al.   CATALYSIS LETTERS

Modern Approaches to Discovering New Hydroxynitrile Lyases for Biocatalysis

(2016) Santosh Kumar Padhi   CHEMBIOCHEM

What are the Limitations of Enzymes in Synthetic Organic Chemistry?

(2016) Manfred T. Reetz   CHEMICAL RECORD

Engineering a more sustainable world through catalysis and green chemistry

(2016) Roger A. Sheldon   Journal of the Royal Society Interface

Recent advances and challenges in the heterologous production of microbial nitrilases for biocatalytic applications

(2016) Ludmila Martínková et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Hydrogen Cyanide in the Rhizosphere: Not Suppressing Plant Pathogens, but Rather Regulating Availability of Phosphate

(2016) Tomaž Rijavec et al.   Frontiers in Microbiology

Cyanide hydratases and cyanide dihydratases: emerging tools in the biodegradation and biodetection of cyanide

(2015) Ludmila Martínková et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The maize cytochrome P450 CYP79A61 produces phenylacetaldoxime and indole-3-acetaldoxime in heterologous systems and might contribute to plant defense and auxin formation

(2015) Sandra Irmisch et al.   BMC PLANT BIOLOGY

Enzymatic cascade synthesis of (S)-2-hydroxycarboxylic amides and acids: Cascade reactions employing a hydroxynitrile lyase, nitrile-converting enzymes and an amidase

(2015) Fred van Rantwijk et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Biosynthetic Pathway for the Cyanide-Free Production of Phenylacetonitrile in Escherichia coli by Utilizing Plant Cytochrome P450 79A2 and Bacterial Aldoxime Dehydratase

(2014) Yuta Miki et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Improvement of the amides forming capacity of the arylacetonitrilase from Pseudomonas fluorescens EBC191 by site-directed mutagenesis

(2014) Olga Sosedov et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Improvement of Alcaligenes faecalis Nitrilase by Gene Site Saturation Mutagenesis and Its Application in Stereospecific Biosynthesis of (R)-(−)-Mandelic Acid

(2014) Zhi-Qiang Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Structural insights into enzymatic activity and substrate specificity determination by a single amino acid in nitrilase from Syechocystis sp. PCC6803

(2014) Lujia Zhang et al.   JOURNAL OF STRUCTURAL BIOLOGY

Metabolic engineering of microorganisms for the production of L-arginine and its derivatives

(2014) Jae Ho Shin et al.   Microbial Cell Factories

Activity improvement of a regioselective nitrilase from Acidovorax facilis and its application in the production of 1-(cyanocyclohexyl) acetic acid

(2014) Xin-Hong Zhang et al.   PROCESS BIOCHEMISTRY

Crystal structure of aldoxime dehydratase and its catalytic mechanism involved in carbon-nitrogen triple-bond synthesis

(2013) J. Nomura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The combi-CLEA approach: enzymatic cascade synthesis of enantiomerically pure (S)-mandelic acid

(2013) Andrzej Chmura et al.   TETRAHEDRON-ASYMMETRY

Application of a RecombinantEscherichia coliWhole-Cell Catalyst Expressing Hydroxynitrile Lyase and Nitrilase Activities in Ionic Liquids for the Production of (S)-Mandelic Acid and (S)-Mandeloamide

(2012) Stefanie Baum et al.   ADVANCED SYNTHESIS & CATALYSIS

Enzymatic Synthesis of Chiral Phenylalanine Derivatives by a Dynamic Kinetic Resolution of Corresponding Amide and Nitrile Substrates with a Multi-Enzyme System

(2012) Kazuyuki Yasukawa et al.   ADVANCED SYNTHESIS & CATALYSIS

Engineering specialized metabolic pathways—is there a room for enzyme improvements?

(2012) Arren Bar-Even et al.   CURRENT OPINION IN BIOTECHNOLOGY

Nitrilases in nitrile biocatalysis: recent progress and forthcoming research

(2012) Jin-Song Gong et al.   Microbial Cell Factories

Synthetic metabolic engineering-a novel, simple technology for designing a chimeric metabolic pathway

(2012) Xiaoting Ye et al.   Microbial Cell Factories

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Dynamic Kinetic Resolution of α-Aminonitriles to Form Chiral α-Amino Acids

(2011) Kazuyuki Yasukawa et al.   ADVANCED SYNTHESIS & CATALYSIS

Purification and characterization of heterologously expressed nitrilases from filamentous fungi

(2011) Alena Petříčková et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Constructing de Novo Biosynthetic Pathways for Chemical Synthesis inside Living Cells

(2011) Amy M. Weeks et al.   BIOCHEMISTRY

Aldoxime Dehydratase: Probing the Heme Environment Involved in the Synthesis of the Carbon–Nitrogen Triple Bond

(2011) Eftychia Pinakoulaki et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Cyanogenic glucosides in the biological warfare between plants and insects: The Burnet moth-Birdsfoot trefoil model system

(2011) Mika Zagrobelny et al.   PHYTOCHEMISTRY

Construction and Application of Variants of the Pseudomonas fluorescens EBC191 Arylacetonitrilase for Increased Production of Acids or Amides

(2010) O. Sosedov et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Nitrile hydratases (NHases): At the interface of academia and industry

(2010) Shreenath Prasad et al.   BIOTECHNOLOGY ADVANCES

Biotransformations with nitrilases

(2010) Ludmila Martínková et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Directed evolution of Alcaligenes faecalis nitrilase

(2010) Ulrike Schreiner et al.   ENZYME AND MICROBIAL TECHNOLOGY

Identification of Amino Acid Residues Responsible for the Enantioselectivity and Amide Formation Capacity of the Arylacetonitrilase from Pseudomonas fluorescens EBC191

(2009) C. Kiziak et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Multi-enzymatic synthesis

(2009) Fernando Lopez-Gallego et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Evolution of nitrilases in glucosinolate-containing plants

(2009) Tim Janowitz et al.   PHYTOCHEMISTRY

Amidases: versatile enzymes in nature

(2009) Monica Sharma et al.   REVIEWS IN ENVIRONMENTAL SCIENCE AND BIO-TECHNOLOGY

Nitrilase enzymes and their role in plant-microbe interactions

(2009) Andrew J. M. Howden et al.   Microbial Biotechnology

Cyanogenesis in plants and arthropods

(2008) Mika Zagrobelny et al.   PHYTOCHEMISTRY