Single-Molecule Tethered Particle Motion: Stepwise Analyses of Site-Specific DNA Recombination

Coiled-coil interactions mediate serine integrase directionality

(2017) Kushol Gupta et al.   NUCLEIC ACIDS RESEARCH

Recombination directionality factor gp3 binds ϕC31 integrase via the zinc domain, potentially affecting the trajectory of the coiled-coil motif

(2017) Paul C M Fogg et al.   NUCLEIC ACIDS RESEARCH

Crossover-site sequence and DNA torsional stress control strand interchanges by the Bxb1 site-specific serine recombinase

(2016) Ross A. Keenholtz et al.   NUCLEIC ACIDS RESEARCH

Single-molecule analysis of ϕC31 integrase-mediated site-specific recombination by tethered particle motion

(2016) Hsiu-Fang Fan et al.   NUCLEIC ACIDS RESEARCH

FtsK translocation permits discrimination between an endogenous and an imported Xer/difrecombination complex

(2016) Florian Fournes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction

(2016) Gurunathan Laxmikanthan et al.   eLife

Condensation transition and forced unravelling of DNA-histone H1 toroids: a multi-state free energy landscape

(2015) A H Mack et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Single molecule TPM analysis of the catalytic pentad mutants of Cre and Flp site-specific recombinases: contributions of the pentad residues to the pre-chemical steps of recombination

(2015) Hsiu-Fang Fan et al.   NUCLEIC ACIDS RESEARCH

Probing a label-free local bend in DNA by single molecule tethered particle motion

(2015) A. Brunet et al.   NUCLEIC ACIDS RESEARCH

Assembly, translocation, and activation of XerCD-difrecombination by FtsK translocase analyzed in real-time by FRET and two-color tethered fluorophore motion

(2015) Peter F. J. May et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone Chaperone-Mediated Nucleosome Assembly Process

(2015) Hsiu-Fang Fan et al.   PLoS One

Effect of Temperature on the Intrinsic Flexibility of DNA and Its Interaction with Architectural Proteins

(2014) Rosalie P. C. Driessen et al.   BIOCHEMISTRY

Tethered Fluorophore Motion: Studying Large DNA Conformational Changes by Single-fluorophore Imaging

(2014) Peter F.J. May et al.   BIOPHYSICAL JOURNAL

A biomechanical mechanism for initiating DNA packaging

(2014) Haowei Wang et al.   NUCLEIC ACIDS RESEARCH

Multiple LacI-mediated loops revealed by Bayesian statistics and tethered particle motion

(2014) Stephanie Johnson et al.   NUCLEIC ACIDS RESEARCH

Using Single-Molecule Approaches To Study Archaeal DNA-Binding Protein Alba1

(2013) Yen-Wen Lu et al.   BIOCHEMISTRY

Organization of DNA Partners and Strand Exchange Mechanisms during Flp Site-Specific Recombination Analyzed by Difference Topology, Single Molecule FRET and Single Molecule TPM

(2013) Chien-Hui Ma et al.   JOURNAL OF MOLECULAR BIOLOGY

Direct Observation of RecBCD Helicase as Single-Stranded DNA Translocases

(2013) Cinya Chung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single molecule analysis of DNA wrapping and looping by a circular 14mer wheel of the bacteriophage 186 CI repressor

(2013) Haowei Wang et al.   NUCLEIC ACIDS RESEARCH

TPM analyses reveal that FtsK contributes both to the assembly and the activation of the XerCD-dif recombination synapse

(2013) Cheikh Tidiane Diagne et al.   NUCLEIC ACIDS RESEARCH

Real-time single-molecule tethered particle motion analysis reveals mechanistic similarities and contrasts of Flp site-specific recombinase with Cre and   Int

(2013) H.-F. Fan et al.   NUCLEIC ACIDS RESEARCH

Attachment site recognition and regulation of directionality by the serine integrases

(2013) Karen Rutherford et al.   NUCLEIC ACIDS RESEARCH

Conformational transitions during FtsK translocase activation of individual XerCD-dif recombination complexes

(2013) P. Zawadzki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-throughput single-molecule analysis of DNA–protein interactions by tethered particle motion

(2012) Thomas Plénat et al.   NUCLEIC ACIDS RESEARCH

Real-time single-molecule tethered particle motion experiments reveal the kinetics and mechanisms of Cre-mediated site-specific recombination

(2012) Hsiu-Fang Fan   NUCLEIC ACIDS RESEARCH

Capturing reaction paths and intermediates in Cre-loxP recombination using single-molecule fluorescence

(2012) J. N. M. Pinkney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gated rotation mechanism of site-specific recombination by  C31 integrase

(2012) F. J. Olorunniji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HU Protein Induces Incoherent DNA Persistence Length

(2011) Guy Nir et al.   BIOPHYSICAL JOURNAL

Single-molecule analysis reveals the molecular bearing mechanism of DNA strand exchange by a serine recombinase

(2011) H. Bai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-molecule Approaches to Probe the Structure, Kinetics, and Thermodynamics of Nucleoprotein Complexes That Regulate Transcription

(2010) Laura Finzi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sin Resolvase Catalytic Activity and Oligomerization State are Tightly Coupled

(2010) Kent W. Mouw et al.   JOURNAL OF MOLECULAR BIOLOGY

Requirements for catalysis in the Cre recombinase active site

(2010) Bryan Gibb et al.   NUCLEIC ACIDS RESEARCH

Studying RecBCD Helicase Translocation Along χ-DNA Using Tethered Particle Motion with a Stretching Force

(2009) Hsiu-Fang Fan et al.   BIOPHYSICAL JOURNAL

Mechanical Constraints on Hin Subunit Rotation Imposed by the Fis/Enhancer System and DNA Supercoiling during Site-Specific Recombination

(2009) Gautam Dhar et al.   MOLECULAR CELL

Dissecting protein-induced DNA looping dynamics in real time

(2009) Niels Laurens et al.   NUCLEIC ACIDS RESEARCH

Concentration and Length Dependence of DNA Looping in Transcriptional Regulation

(2009) Lin Han et al.   PLoS One

Biology, one molecule at a time

(2009) Achillefs N. Kapanidis et al.   TRENDS IN BIOCHEMICAL SCIENCES

Synapsis and catalysis by activated Tn3 resolvase mutants

(2008) F. J. Olorunniji et al.   NUCLEIC ACIDS RESEARCH

A motif in the C-terminal domain of ϕC31 integrase controls the directionality of recombination

(2008) Paul A. Rowley et al.   NUCLEIC ACIDS RESEARCH