Article
Environmental Sciences
Helena Sandoval-Insausti, Yu-Han Chiu, Dong Hoon Lee, Siwen Wang, Jaime E. Hart, Lidia Minguez-Alarcon, Francine Laden, Andres V. Ardisson Korat, Brenda Birmann, A. Heather Eliassen, Walter C. Willett, Jorge E. Chavarro
Summary: The study found that overall exposure to pesticides through FV intake is not related to cancer risk, although associations with specific chemicals or sub-types of specific cancers cannot be ruled out.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Robert B. Hood, Donghai Liang, Yu-Han Chiu, Helena Sandoval-Insausti, Jorge E. Chavarro, Dean Jones, Russ Hauser, Audrey J. Gaskins
Summary: This study utilized metabolomics to analyze the alterations in the serum metabolome associated with high and low pesticide residue intake from fruits and vegetables. The findings suggest that there are different metabolic pathways associated with high and low pesticide residue FV intake, supporting the disparate health effects associated with these exposures.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Aoife E. Mcnamara, Xiaofei Yin, Cassandra Collins, Lorraine Brennan
Summary: It has been well-established that consuming cruciferous and brassica vegetables is correlated with reduced rates of negative health outcomes. This study aimed to identify biomarkers of broccoli intake and examine the dose-response relationship using metabolomic approaches. The results showed that urinary S-methyl cysteine sulfoxide (SMCSO) and several LC-MS features appeared as potentially promising biomarkers of broccoli consumption.
Article
Environmental Sciences
Didem Kazar Soydan, Nalan Turgut, Melis Yalcin, Cafer Turgut, Perihan Binnur Kurt Karakus
Summary: The study in the Aegean region of Turkey from 2012 to 2016 found pesticide residues in fruits and vegetables samples, with some exceeding maximum residue limits (MRLs) set by Turkish authorities. Chlorpyrifos, azoxystrobin, and triadimenol were among the pesticides with the highest detected levels.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
David J. Cote, Alaina M. Bever, Yu-Han Chiu, Helena Sandoval-Insausti, Stephanie A. Smith-Warner, Jorge E. Chavarro, Meir J. Stampfer
Summary: This study investigated the association between intake of pesticide residues from fruits and vegetables and glioma. The results showed a significant association between intake of high-residue fruits and vegetables and glioma in one cohort, but not in the other cohorts.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
El-Sayed A. El-Sheikh, Mahmoud M. Ramadan, Ahmed E. El-Sobki, Ali A. Shalaby, Mark R. McCoy, Ibrahim A. Hamed, Mohamed-Bassem Ashour, Bruce D. Hammock
Summary: The use of pesticides in agriculture increases production but can also have harmful effects on human health. This study investigated the levels of pesticide residues in vegetables and fruits from farmers' markets in Sharkia Governorate, Egypt. The results showed that a significant number of samples had pesticide residues exceeding the maximum residual limits. This highlights the importance of continuous monitoring to ensure food safety.
Article
Medicine, General & Internal
Ling Cui, Fang Wang, Yonghong Lin, Min Li
Summary: The study found that infertile couples carrying chromosomal abnormalities undergoing assisted reproductive technology did not show significant differences in cumulative clinical pregnancy rate or cumulative live birth rate compared to infertile couples without chromosomal abnormalities. This data provides important insights for clinical decision-making in ART treatment for couples with chromosomal abnormalities.
ANNALS OF MEDICINE
(2022)
Article
Chemistry, Applied
Chunhao Cao, Wenchuan Guo
Summary: A carbon dots-based fluorescent probe prepared by hydrothermal method can rapidly detect the harm of excessive imidacloprid to the human body, and it has good selectivity, stability, and anti-interference ability. The probe shows excellent performance in detecting imidacloprid in lettuce, cole, spinach, and pakchoi.
Article
Chemistry, Applied
Cristian Rojas, Jose F. Aranda, Elisa Pacheco Jaramillo, Irene Losilla, Piercosimo Tripaldi, Pablo R. Duchowicz, Eduardo A. Castro
Summary: This study developed a computational model to predict the retention time of pesticides detected in fruits and vegetables, using MS data and molecular descriptors. Multiple MLR models were analyzed for consensus, and the optimal model was evaluated based on various criteria. The model was successfully applied for predicting the retention time of an external set of 57 pesticides.
Article
Medicine, General & Internal
Honggan Yi, Man Yang, Haiyu Tang, Mei Lin
Summary: This study found that the rate of pregnancy failure after ART is high, and that maternal age, GnRH-a short protocol, and single embryo transfer may increase the risk of pregnancy failure, while two embryo transfer may reduce the risk.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2022)
Article
Chemistry, Applied
Duoduo Jiang, Zhipeng Cheng, Xixi Chen, Fengshou Dong, Jun Xu, Xingang Liu, Xiaohu Wu, Xinglu Pan, Xiaokang An, Yongquan Zheng
Summary: This study investigated the residues of eight common-used pesticide adjuvants in vegetables in North China from 2014 to 2016, finding that the residue levels of total PAs in vegetables from markets and farms were 500 and 661 mu g/kg, respectively. The highest residues of total PAs were found in cauliflowers and spinaches, with Tristyrylphenol ethoxylates dominating the concentrations in most vegetable species. As for human health risks, exposure to TPE and NP via vegetables for adults was deemed acceptable, while the estimated daily intakes of the other six PAs were unlikely to pose a threat to human health.
Review
Plant Sciences
Kannan Maharajan, Qing Xia, Xiuying Duan, Pengfei Tu, Yun Zhang, Kechun Liu
Summary: Zishen Yutai Pill (ZYP) is a widely used Traditional Chinese Medicine in Assisted Reproductive Technology (ART) medications, and has shown potential therapeutic effects in improving fertility and pregnancy rates. Clinical studies have demonstrated its curative effects on various reproductive disorders by regulating reproductive functions such as ovulation, follicle development, and hormonal balance.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Review
Nutrition & Dietetics
Widad Zeidan, Haneen Taweel, Aisha Shalash, Abdullatif Husseini
Summary: This systematic review evaluates fruit and vegetable intake among adolescents in Arab countries, and highlights the inadequate consumption and increased risk of poor health outcomes. It also assesses the dietary assessment tools used to measure intake.
INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY
(2023)
Article
Oncology
Shu Peng, Hong Sun, Jie Zheng, Ni Zeng, Fangxin Peng
Summary: The study on elderly infertility patients undergoing ART revealed that the main risk factors for pregnancy failure are related to woman's age, numbers of embryos transferred, previous pregnancy abortion history, numbers of high-quality embryos, and EMT on hCG day.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2021)
Article
Environmental Sciences
Helena Sandoval-Insausti, Yu-Han Chiu, Yi-Xin Wang, Jaime E. Hart, Shilpa N. Bhupathiraju, Lidia Minguez-Alarcon, Ming Ding, Walter C. Willett, Francine Laden, Jorge E. Chavarro
Summary: The study found that consuming fruits and vegetables with low pesticide residues can reduce the overall risk of mortality, while consuming fruits and vegetables with high pesticide residues is not associated with mortality risk. This pattern was consistent across the three most frequent causes of death, including cardiovascular disease, cancer, and respiratory diseases.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Nutrition & Dietetics
Mariel Arvizu, Lidia Minguez-Alarcon, Siwen Wang, Makiko Mitsunami, Jennifer J. Stuart, Janet W. Rich-Edwards, Bernard Rosner, Jorge E. Chavarro
Summary: This study found that pre-pregnancy intake of trans fatty acids was associated with a higher risk of hypertensive disorders of pregnancy (HDP), while intake of monounsaturated fatty acids, saturated fats, and total fats were unrelated to HDP. High intake of long-chain omega-3 fatty acids was associated with a lower risk of HDP.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Obstetrics & Gynecology
Albert Salas-Huetos, Mariel Arvizu, Lidia Minguez-Alarcon, Makiko Mitsunami, Jordi Ribas-Maynou, Marc Yeste, Jennifer B. Ford, Irene Souter, Jorge E. Chavarro
Summary: This study found that women's consumption of omega-3 fatty acids and omega-3-rich foods may improve the probability of conception by decreasing the risk of pregnancy loss. Additionally, men's intake of omega-3 fatty acids may influence semen quality.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Environmental Sciences
Jenny L. Carwile, Shravanthi M. Seshasayee, Katherine A. Ahrens, Russ Hauser, Jorge E. Chavarro, Abby F. Fleisch
Summary: The study found that children with diets characterized by higher consumption of certain starchy vegetables, quick breads, and citrus juices prepared at a restaurant had higher urinary phthalate metabolites. More detailed information on the specific methods of food processing and details on packaging materials is needed.
ENVIRONMENTAL RESEARCH
(2022)
Article
Oncology
Andres V. Ardisson Korat, Yu-Han Chiu, Kimberly A. Bertrand, Shumin Zhang, Mara M. Epstein, Bernard A. Rosner, Stephanie Chiuve, Hannia Campos, Edward L. Giovannucci, Jorge E. Chavarro, Brenda M. Birmann
Summary: Published studies on the association between polyunsaturated fatty acid (PUFA) intake and non-Hodgkin lymphoma (NHL) risk have yielded inconsistent results. This nested case-control study, involving participants from the Nurses' Health Study and Health Professionals Follow-Up Study, found no overall association between red blood cell (RBC) membrane PUFA levels and NHL risk. However, certain PUFA were associated with specific types of lymphoma, and the reasons for these unexpected associations remain unclear.
LEUKEMIA & LYMPHOMA
(2022)
Article
Medicine, General & Internal
Keyi Si, Yang Hu, Molin Wang, Caroline M. Apovian, Jorge E. Chavarro, Qi Sun
Summary: This study suggests that individuals with obesity who attempted to lose weight, regardless of the weight loss strategies used, tended to gain less body weight and have a lower risk of diabetes. In contrast, lean individuals who intentionally lost weight tended to gain more weight and have a higher risk of diabetes.
Article
Nutrition & Dietetics
Jiaxi Yang, Deirdre K. Tobias, Shanshan Li, Shilpa N. Bhupathiraju, Sylvia H. Ley, Stefanie N. Hinkle, Frank Qian, Zhangling Chen, Yeyi Zhu, Wei Bao, Jorge E. Chavarro, Frank B. Hu, Cuilin Zhang
Summary: The study found that among females with a history of GDM, greater consumption of caffeinated coffee was associated with a lower risk of T2D.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Obstetrics & Gynecology
Makiko Mitsunami, Lidia Minguez-Alarcon, Andrea A. Florio, Siwen Wang, Jill A. Attaman, Irene Souter, Russ Hauser, Jorge E. Chavarro
Summary: This study aimed to investigate the association between intake of soy food and isoflavone with ovarian reserve. Previous studies on the relationship between soy intake and human fertility are inconsistent. However, no studies have evaluated the relationship between soy or isoflavone intake with markers of ovarian reserve other than follicle-stimulating hormone (FSH).
FERTILITY AND STERILITY
(2023)
Article
Obstetrics & Gynecology
Lidia Minguez-Alarcon, Paige L. Williams, Irene Souter, Jennifer B. Ford, Ramy Abou Ghayda, Russ Hauser, Jorge E. Chavarro
Summary: Men working non-daytime/rotating shifts and those with physically demanding jobs have higher sperm concentration and total sperm count as well as higher estradiol and total testosterone concentrations.
HUMAN REPRODUCTION
(2023)
Article
Nursing
Melissa Perez Capotosto, Christopher S. Lee, Corrine Y. Jurgens, Siwen Wang, Makiko Mitsunami, Brittany M. Charlton, Jorge E. Chavarro
Summary: This study aimed to identify predictors of fertility-awareness-based method use among women trying to conceive or contemplating pregnancy. The results showed that the duration of ongoing pregnancy attempt and gravidity were the only significant predictors for the number of fertility-awareness-based methods used among women actively trying to conceive, while partnership was the only significant predictor of the number of fertility-awareness-based methods among women contemplating pregnancy.
Article
Cardiac & Cardiovascular Systems
Leslie V. Farland, Yi-Xin Wang, Audrey J. Gaskins, Janet W. Rich-Edwards, Siwen Wang, Maria Christine Magnus, Jorge E. Chavarro, Kathryn M. Rexrode, Stacey A. Missmer
Summary: Infertility is associated with an increased risk of coronary heart disease, but not stroke. The risk differs depending on the age at first infertility diagnosis and the specific cause of infertility.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Obstetrics & Gynecology
Siwen Wang, Audrey J. Gaskins, Leslie V. Farland, Dan Zhang, Brenda M. Birmann, Janet W. Rich-Edwards, Yi-Xin Wang, Rulla M. Tamimi, Stacey A. Missmer, Jorge E. Chavarro
Summary: This prospective cohort study examined the association between infertility and the incidence of invasive cancer in women. It found that women who reported infertility had a higher risk of developing cancer, especially obesity-related reproductive cancers. The risk was also higher for women who first reported infertility at a younger age.
FERTILITY AND STERILITY
(2023)
Article
Obstetrics & Gynecology
N. Jimenez-Cardozo, M. Mitsunami, L. Minguez-Alarcon, E. Ortiz-Panozo, S. Wang, I Souter, R. Hauser, J. E. Chavarro
Summary: This study found that supplemental iron intake above 45 mg/day is associated with lower ovarian reserve among women seeking fertility care.
HUMAN REPRODUCTION
(2023)
Article
Obstetrics & Gynecology
Robert B. Hood, Donghai Liang, Youran Tan, Jennifer B. Ford, Irene Souter, Jorge E. Chavarro, Dean P. Jones, Russ Hauser, Audrey J. Gaskins
Summary: This study identified the metabolic pathways and metabolites in the serum and follicular fluid that are associated with peak estradiol levels and the number of mature oocytes. The serum metabolome mainly involves fatty acid and amino acid pathways, while the follicular fluid metabolome mainly involves lipid, vitamin, and hormone pathways. These findings provide insights into the biological mechanisms underlying follicular and oocyte development.
HUMAN REPRODUCTION
(2023)
Article
Public, Environmental & Occupational Health
Sheryl L. Rifas-Shiman, Izzuddin M. Aris, Karen M. Switkowski, Jessica Young, Abby F. Fleisch, Tamarra James-Todd, Ami R. Zota, Wei Perng, Marie-France Hivert, Janet W. Rich-Edwards, Melissa Perez Capotosto, Jorge E. Chavarro, Emily Oken
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Endocrinology & Metabolism
Diana C. C. Soria-Contreras, Izzuddin M. M. Aris, Sheryl L. L. Rifas-Shiman, Wei Perng, Marie-France Hivert, Jorge E. E. Chavarro, Emily Oken
Summary: This study aimed to evaluate the associations of age at first birth and parity with weight, waist circumference (WC), and body fat across midlife. A secondary data analysis was conducted with 735 participants from Project Viva. The results showed that women who had their first birth before age 23 years or after age 40 years, as well as those with four or more births, had a higher trajectory of weight, WC, and body fat after their final birth.