Review
Biochemistry & Molecular Biology
Dumitru Constantin-Teodosiu, Despina Constantin
Summary: Muscle fatigue can decrease the capacity of muscles to complete tasks over time, with short-lasting fatigue often caused by overtraining, undertraining, or physical injury, while persistent and severe fatigue may be associated with pathological states or chronic exposure to certain substances.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Physiology
Elena M. Yee, Carson T. Hauser, Jonathan J. Petrocelli, Naomi M. M. P. de Hart, Patrick J. Ferrara, Princess Bombyck, Zachary J. Fennel, Lisha van Onselen, Sohom Mookerjee, Katsuhiko Funai, J. David Symons, Micah J. Drummond
Summary: This study found that 12 weeks of treadmill training in old male mice improved endothelial function, physical performance, and overall body composition, but had limited impact on skeletal muscle remodeling at baseline or in response to recovery following disuse atrophy.
FRONTIERS IN PHYSIOLOGY
(2023)
Review
Orthopedics
Masoud Rahmati, Julien Gondin, Fatemeh Malakoutinia
Summary: NMES has shown to be effective in improving quadriceps muscle strength in young adults, but its impact on muscle mass and effectiveness in older adults needs further investigation and confirmation through high-quality RCTs with larger sample sizes.
Article
Medicine, General & Internal
Jun Chao Zeng, Yu Ying Yang, Yan Shen
Summary: This study investigated the electrophysiological indexes of pelvic floor muscles (PFM) in second trimester postpartum women after 2 months of pelvic floor rehabilitation. The results showed that biofeedback plus electrical stimulation had a better effect on PFM function in second pregnant women compared to Kegel exercises in the short term. However, there was no significant difference between the two training methods in the long term recovery of PFM.
Article
Biochemistry & Molecular Biology
Mark R. Viggars, Hazel Sutherland, Christopher P. Cardozo, Jonathan C. Jarvis
Summary: Transcriptional assessments of identical nerve-stimulated resistance exercise in mice and rats reveal concordant and discordant gene regulation and pathways related to muscle growth.
Review
Endocrinology & Metabolism
Yuntian Shen, Ming Li, Kexin Wang, Guangdong Qi, Hua Liu, Wei Wang, Yanan Ji, Mengyuan Chang, Chunyan Deng, Feng Xu, Mi Shen, Hualin Sun
Summary: Diabetes mellitus is a chronic disease that can lead to complications such as kidney disease, cardiovascular disease, neuropathy, and skeletal muscle atrophy. Understanding the molecular regulatory mechanisms of diabetic muscular atrophy is important in developing new treatment strategies.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Oncology
Georgios Mavropalias, Marc Sim, Dennis R. Taaffe, Daniel A. Galvao, Nigel Spry, William J. Kraemer, Keijo Hakkinen, Robert U. Newton
Summary: Cancer-induced muscle wasting, or cancer cachexia, is a common and devastating syndrome. Research on using exercise to manage CC is limited, but different modes and subtypes of exercise can counteract the mechanisms and symptoms of CC.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2022)
Article
Pharmacology & Pharmacy
Kelly D. Atkins, C. Scott Bickel
Summary: Interventions using Functional Electrical Stimulation (FES) show promise in slowing muscle atrophy, facilitating muscle hypertrophy, and improving muscle performance in individuals with spinal cord injury.
CURRENT OPINION IN PHARMACOLOGY
(2021)
Article
Immunology
Catherine M. Jankowski, Melissa P. Wilson, Samantha MaWhinney, Jane Reusch, Leslie Knaub, Sara Hull, Kristine M. Erlandson
Summary: The study found that individuals with HIV had blunted mitochondrial adaptations to exercise compared to uninfected controls, suggesting the need for different types of exercise-induced stimulation to improve mitochondrial function in this population.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Review
Pharmacology & Pharmacy
Kexin Wang, Qingyuan Liu, Mingyu Tang, Guangdong Qi, Chong Qiu, Yan Huang, Weiran Yu, Wei Wang, Hualin Sun, Xuejun Ni, Yuntian Shen, Xingxing Fang
Summary: Chronic kidney disease (CKD) is a high-risk chronic catabolic disease with high morbidity and mortality. CKD is accompanied by many complications, leading to a poor quality of life and even threatening the life of patients. Muscle atrophy is a common complication of CKD.
BIOCHEMICAL PHARMACOLOGY
(2023)
Article
Medicine, General & Internal
Hyun-Joon Yoo, Sangsoo Park, Sejun Oh, Munjeong Kang, Yongha Seo, Byung Gon Kim, Sang-Heon Lee
Summary: This study aimed to evaluate the immediate clinical effects of superimposing EMS on strength training compared with conventional exercise in healthy non-athletic adults. The results showed that EMS was more effective in stimulating muscle contractions compared to conventional training. This suggests that EMS may be a safe and reasonable modality for improving physical fitness in healthy individuals.
Article
Chemistry, Analytical
Tomonori Sawada, Hiroki Okawara, Daisuke Nakashima, Kaito Ikeda, Joji Nagahara, Haruki Fujitsuka, Sosuke Hoshino, Yuta Maeda, Yoshinori Katsumata, Masaya Nakamura, Takeo Nagura
Summary: A novel exercise modality combined with electrical muscle stimulation (EMS) has been reported to increase cardiovascular and metabolic responses. This study aimed to examine the effect of constant load pedaling exercise combined with EMS by measuring sweat lactate levels.
Review
Sport Sciences
Zi-Siong Chow, Ashleigh T. Moreland, Helen Macpherson, Wei-Peng Teo
Summary: Resistance exercise has been shown to induce neuroplastic changes within the central nervous system and improve cognitive functioning, making it a potential novel adjuvant rehabilitation strategy for populations with neurological impairments. Proper manipulation of exercise parameters is crucial in enhancing cognitive health through resistance training.
Article
Medicine, General & Internal
Tadayoshi Nonoyama, Hiroko Shigemi, Masafumi Kubota, Akihiko Matsumine, Kenji Shigemi, Tamotsu Ishizuka
Summary: NMES can prevent muscle atrophy in critically ill older patients, especially in the pre-old age group. However, further research is needed to determine the impact of NMES on the physical functioning of older patients in the ICU.
Article
Multidisciplinary Sciences
Mon-Chien Lee, Chin-Shan Ho, Yi-Ju Hsu, Ming-Fang Wu, Chi-Chang Huang
Summary: In recent years, electrical muscle stimulation (EMS) devices have been used as a complementary training technique for physical fitness and rehabilitation. This study aimed to investigate the effects of frequency-specific EMS combined with resistance exercise on muscle mass, strength, body composition, and fatigue-related parameters. The results showed that this combined training method significantly improved muscle mass, strength, and reduced body fat.