Article
Plant Sciences
Mousona Islam, Takumi Inoue, Mayuka Hiraide, Nobiza Khatun, Akida Jahan, Keiko Kuwata, Sotaro Katagiri, Taishi Umezawa, Izumi Yotsui, Yoichi Sakata, Daisuke Takezawa
Summary: In the moss Physcomitrium patens, the Raf-like protein kinase ARK is an upstream regulator of SnRK2 and activation of ARK by phosphorylation at Ser1029 is essential for ABA and abiotic stress responses. PP2C-A acts as a negative regulator of SnRK2 following ARK activation, providing a prototype mechanism for plant responses to ABA and abiotic stress.
Article
Multidisciplinary Sciences
Fumiyuki Soma, Fuminori Takahashi, Satoshi Kidokoro, Haruka Kameoka, Takamasa Suzuki, Yusaku Uga, Kazuo Shinozaki, Kazuko Yamaguchi-Shinozaki
Summary: Osmotic stresses such as drought and high salinity have negative effects on plant growth and productivity. Abscisic acid (ABA) accumulates in response to osmotic stress and enhances stress tolerance by triggering physiological responses through ABA signaling. B2-RAFs are essential for activating SnRK2s in an ABA-dependent manner under mild osmotic stress, while B3-RAFs enhance SnRK2 activity under severe stress conditions.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Biochemistry & Molecular Biology
Ya-Nan Chang, Zhijuan Wang, Ziyin Ren, Chun-Han Wang, Pengcheng Wang, Jian-Kang Zhu, Xia Li, Cheng-Guo Duan
Summary: The study reveals that NUA and ESD4 act as inhibitors of SnRK2 kinases, negatively regulating plant responses to ABA and drought stress. The mechanism involves the SUMOylation-dependent regulation of SnRK2s.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Jingjing Luo, Wenying Yu, Yuansong Xiao, Yafei Zhang, Futian Peng
Summary: In this study, overexpression of PpSnRK1 alpha gene in tomato was found to improve photosynthetic rates and enhance resistance to low nutrient stress. PpSnRK1 alpha was also found to activate autophagy and regulate the expression of several autophagy-related genes. Additionally, PpSnRK1 alpha may be involved in the regulation of the ABA signaling pathway.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Katarina Luksic, Ana Mucalo, Ana Smolko, Lidija Brkljacic, Luka Marinov, Katarina Hancevic, Maja Ozretic Zokovic, Marijan Bubola, Edi Maletic, Jasminka Karoglan Kontic, Marko Karoglan, Branka Salopek-Sondi, Goran Zdunic
Summary: The biochemical response and gene expression in different grapevine cultivars to water deficit were investigated in this study. The results showed that water deficit significantly increased abscisic acid, salicylic acid, and proline accumulation in the leaves of stressed genotypes. Lipid peroxidation was lower in stressed plants after nine days of water deficit. The cultivar 'Istrian Malvasia' showed the highest and earliest increase in ABA levels, and 'Grasevina' differed significantly from other genotypes in SA content.
Article
Biochemistry & Molecular Biology
Mengyi Chen, Xiaoyang Zhu, Xiaojuan Liu, Caiyu Wu, Canye Yu, Guojian Hu, Lin Chen, Riyuan Chen, Mondher Bouzayen, Mohammed Zouine, Yanwei Hao
Summary: The study characterized the function of SlARF4, a member of the ARF family, under water deficit conditions, showing its involvement in plant responses to water stress and improved resistance capabilities.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Plant Sciences
Jan Roeder, Jinghui Liu, Isabel Doch, Moritz Ruschhaupt, Alexander Christmann, Erwin Grill, Hendrik Helmke, Sabine Hohmann, Stefan Lehr, Jens Frackenpohl, Zhenyu Yang
Summary: Climate change and overexploitation of groundwater resources pose challenges to water demand in agriculture, threatening crop productivity. To enhance future food security, crops with both high water use efficiency and high crop productivity are urgently needed. Recent studies have shown that plants can optimize carbon uptake per water transpired without reducing yields. The plant hormone abscisic acid (ABA) plays a key role in reducing leaf transpiration and increasing water productivity. Therefore, ABA and its more chemically stable agonists have the potential to improve crop water productivity.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Plant Sciences
Mingjing Zhang, Li Liu, Chunxiao Chen, Yang Zhao, Caihong Pang, Min Chen
Summary: The study reveals that FvSnRK2182 is involved in regulating the growth and stress response in plants. It enhances plant resistance to salt stress and ABA by promoting root development and maintaining ion homeostasis.
PLANT CELL REPORTS
(2022)
Review
Plant Sciences
Katarzyna Retzer, Wolfram Weckwerth
Summary: Roots are sensors that have evolved to respond to multiple signals, ensuring the survival of plants. The regulation of root growth responses, particularly directional root growth, varies when exposed to a combination of external stimuli compared to individual stress triggers. The negative phototropic response of roots has been shown to interfere with the adaptation of directional root growth under additional gravitropic, halotropic, or mechanical triggers. This review provides an overview of the cellular, molecular, and signaling mechanisms involved in the regulation of directional root growth in response to external stimuli. It also summarizes recent experimental approaches to identify which root growth responses are regulated by specific triggers. Lastly, it discusses the potential application of this knowledge in plant breeding.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Agronomy
Zhenhua Wei, Liang Fang, Xiangnan Li, Jie Liu, Fulai Liu
Summary: This study demonstrates that the endogenous ABA level plays a crucial role in modulating the water use efficiency (WUE) and nitrogen use efficiency (NUE) of barley and tomato plants in response to elevated CO2 levels, providing insights into the physiological mechanisms of crop plants adapting to future climate change scenarios.
AGRICULTURAL WATER MANAGEMENT
(2021)
Article
Multidisciplinary Sciences
Yoshiaki Kamiyama, Misaki Hirotani, Shinnosuke Ishikawa, Fuko Minegishi, Sotaro Katagiri, Conner J. Rogan, Fuminori Takahashi, Mika Nomoto, Kazuya Ishikawa, Yutaka Kodama, Yasuomi Tada, Daisuke Takezawa, Jeffrey C. Anderson, Scott C. Peck, Kazuo Shinozaki, Taishi Umezawa
Summary: The study identified Raf36 and Raf22 protein kinases in plants as regulators of ABA signal transduction under multiple mechanisms to suppress ABA response. Through a series of experiments, it was found that they regulate ABA response through phosphorylation and other mechanisms under ABA stimulation, playing an important role in plants' adaptation to stress conditions.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biochemistry & Molecular Biology
Miaomiao Li, Ting Wu, Shuhan Wang, Tianqi Duan, Siqi Huang, Yanjie Xie
Summary: SnRK2.6 functions as a molecular switch for the ABA signal-transduction pathway and its activity is regulated by post-translational modifications, such as persulfidation and phosphorylation. Persulfidation promotes ABA signaling initiation while phosphorylation inhibits ABA signaling. These findings expand our understanding of SnRK2.6 regulation and provide insights into the fine-tuned mechanism of ABA signaling.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Hui Liu, Songbo Song, Hui Zhang, Yanhua Li, Liangjie Niu, Jinghua Zhang, Wei Wang
Summary: Drought is a global threat that affects agricultural production. Plants have evolved several adaptive strategies to cope with drought, among which stomatal closure is a critical mechanism. Abscisic acid, reactive oxygen species, and calcium ion play pivotal roles in controlling stomatal closure.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Marcos Fernando Basso, Julia Almeida Costa, Thuanne Pires Ribeiro, Fabricio Barbosa Monteiro Arraes, Isabela Tristan Lourenco-Tessutti, Amanda Ferreira Macedo, Maysa Rosa das Neves, Sarah Muniz Nardeli, Luis Willian Arge, Carlos Eduardo Aucique Perez, Paolo Lucas Rodrigues Silva, Leonardo Lima Pepino de Macedo, Maria Eugenia Lisei-de-Sa, Regina Maria Santos Amorim, Eduardo Romano de Campos Pinto, Maria Cristina Mattar Silva, Carolina Vianna Morgante, Eny Iochevet Segal Floh, Marcio Alves-Ferreira, Maria Fatima Grossi-de-Sa
Summary: Overexpression of the CaHB12 gene enhances plant tolerance to drought stress and may enhance defense responses to drought through regulating genes related to the ABA signaling pathway. The decrease in IAA levels resulting from CaHB12 overexpression can prevent leaf abscission in plants under stress. These findings provide important insights for breeding cotton varieties and conducting field trials on water deficit tolerance.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Plant Sciences
Yafei Li, Xuan Xian, Luqin Guo, Jialong Zhang, Chaolin Gan, Zhirong Wang, Hongfei Li, Xingsheng Li, Xiaowei Yuan, Na Zhang, Yang-Dong Guo
Summary: The research found that the CsbZIP50 gene can enhance drought tolerance in cucumber by regulating the expression of drought-responsive genes and ROS levels.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2022)
Article
Plant Sciences
X. P. Wang, Q. Q. Li, Z. M. Pei, S. C. Wang
BIOLOGIA PLANTARUM
(2018)
Article
Developmental Biology
Xinlong Jiang, Wenzhong An, Xiao Yang, Shiliang Ma, Dajia Wang, Shuang Tang
GENE EXPRESSION PATTERNS
(2018)
Article
Medicine, Research & Experimental
Meng Ji, Shuang Tang, Wenhua Pei, Mingming Ning, Yuehui Ma, Xiangchen Li, Weijun Guan
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
(2018)
Article
Plant Sciences
Xianling Wang, Lu Wang, Yu Wang, Huan Liu, Dan Hu, Ning Zhang, Shaobin Zhang, Huiying Cao, Qijiang Cao, Zhihong Zhang, Shuang Tang, Dandan Song, Che Wang
FRONTIERS IN PLANT SCIENCE
(2018)
Correction
Plant Sciences
Xianling Wang, Yu Wang, Lu Wang, Huan Liu, Bing Zhang, Qijiang Cao, Xinyu Liu, Shuangtian Bi, Yanling Lv, Qiuyang Wang, Shaobin Zhang, Ming He, Shuang Tang, Shuo Yao, Che Wang
FRONTIERS IN PLANT SCIENCE
(2018)
Article
Environmental Sciences
Wenyang Cai, Xiao Yang, Xiangchen Li, Hongtu Li, Shuo Wang, Zhengchao Wu, Mingxi Yu, Shiliang Ma, Shuang Tang
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2020)
Article
Plant Sciences
Xianling Wang, Shuangtian Bi, Lu Wang, Hongpeng Li, Bi-Ao Gao, Shanjin Huang, Xiaolu Qu, Jianing Cheng, Shucai Wang, Caiyuan Liu, Yikuo Jiang, Bing Zhang, Xiaoyu Liu, Shaobin Zhang, Ying Fu, Zhihong Zhang, Che Wang
Article
Oncology
Chenghao Fu, Zhonglin Fu, Chunying Jiang, Chao Xia, Yiwei Zhang, Xingju Gu, Kexin Zheng, Dayu Zhou, Shuang Tang, Shuxia Lyu, Shiliang Ma
Summary: PMN-MDSCs in tumor-bearing hosts exhibit functional and phenotypic heterogeneities, hindering clinical therapeutic decisions.
Article
Oncology
Qilong Li, Mohan Li, Kexin Zheng, Shuang Tang, Shiliang Ma
Summary: This study investigated the spatiotemporal expression of alpha-SMA-positive CAFs in TNBC tumors, correlation between tumor volume and fibrosis, molecular characteristics of different fibrosis levels, and drug sensitivity based on alpha-SMA expression. Results showed upregulation of myogenesis, TGF-beta, and Notch pathways in TNBC patients, with differential drug sensitivity. In vivo experiments revealed stronger inhibitory effect of embelin on tumors with high alpha-SMA expression, suggesting its potential in cancer treatment.
TRANSLATIONAL ONCOLOGY
(2021)
Article
Developmental Biology
Mingxi Yu, Xinlong Jiang, Wenyang Cai, Xiao Yang, Wenzhong An, Mei Zhang, Yan Xu, Bochuan Zhang, Shuang Tang
Summary: In mouse preimplantation embryos, PATJ and MPDZ are key members of the CRB-PALS1-PATJ apical polarity complex, essential for cell polarization and stabilization of apical junctions. Depletion of PATJ and MPDZ leads to impaired blastocyst formation, compromised trophectoderm differentiation and breakdown of apical domain, tight junctions, and actin filaments.