HIF-2α is essential for carotid body development and function

Gene expression analyses reveal metabolic specifications in acute O2 -sensing chemoreceptor cells

(2017) Lin Gao et al.   JOURNAL OF PHYSIOLOGY-LONDON

Physiological Plasticity of Neural-Crest-Derived Stem Cells in the Adult Mammalian Carotid Body

(2017) Valentina Annese et al.   Cell Reports

Cardiovascular adaptation to hypoxia and the role of peripheral resistance

(2017) Andrew S Cowburn et al.   eLife

Endothelial HIF signaling regulates pulmonary fibrosis-associated pulmonary hypertension

(2016) Andrew J. Bryant et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Single cell transcriptome analysis of mouse carotid body glomus cells

(2016) Ting Zhou et al.   JOURNAL OF PHYSIOLOGY-LONDON

The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice

(2016) Pinelopi P. Kapitsinou et al.   MOLECULAR AND CELLULAR BIOLOGY

Oxygen-sensing by arterial chemoreceptors: Mechanisms and medical translation

(2016) José López-Barneo et al.   MOLECULAR ASPECTS OF MEDICINE

Purinergic receptors in the carotid body as a new drug target for controlling hypertension

(2016) Wioletta Pijacka et al.   NATURE MEDICINE

HIF2α–arginase axis is essential for the development of pulmonary hypertension

(2016) Andrew S. Cowburn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Roles of PI3K/AKT/mTOR and MAPK/ERK Signaling Pathways in Human Pheochromocytomas

(2016) Juan Du et al.   International Journal of Endocrinology

Role Of Hif2α Oxygen Sensing Pathway In Bronchial Epithelial Club Cell Proliferation

(2016) Mar Torres-Capelli et al.   Scientific Reports

Regulation of cell proliferation by hypoxia-inducible factors

(2015) Maimon E. Hubbi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway

(2015) Emma J. Hodson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Carotid body oxygen sensing and adaptation to hypoxia

(2015) José López-Barneo et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

An O2-Sensitive Glomus Cell-Stem Cell Synapse Induces Carotid Body Growth in Chronic Hypoxia

(2014) Aida Platero-Luengo et al.   CELL

Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia

(2014) D. Macias et al.   EMBO Molecular Medicine

Paraganglioma and phaeochromocytoma: from genetics to personalized medicine

(2014) Judith Favier et al.   Nature Reviews Endocrinology

Glucose sensing by carotid body glomus cells: potential implications in disease

(2014) Lin Gao et al.   Frontiers in Physiology

The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxia

(2013) Mary E. Slingo et al.   JOURNAL OF APPLIED PHYSIOLOGY

Erythrocytosis and Pulmonary Hypertension in a Mouse Model of HumanHIF2AGain of Function Mutation

(2013) Qiulin Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension

(2013) Fiona D. McBryde et al.   Nature Communications

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

A novel EPAS1/HIF2A germline mutation in a congenital polycythemia with paraganglioma

(2012) Felipe R. Lorenzo et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

HIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5

(2012) Ainara Elorza et al.   MOLECULAR CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

SomaticHIF2AGain-of-Function Mutations in Paraganglioma with Polycythemia

(2012) Zhengping Zhuang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypoxia-inducible factor 2  (HIF-2 ) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension

(2011) Y.-J. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTORC1 Signaling under Hypoxic Conditions Is Controlled by ATM-Dependent Phosphorylation of HIF-1α

(2010) Hakan Cam et al.   MOLECULAR CELL

The Ventilatory Response to Hypoxia in Mammals: Mechanisms, Measurement, and Analysis

(2010) Luc J. Teppema et al.   PHYSIOLOGICAL REVIEWS

Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure

(2009) Kurt R. Stenmark et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FRS2α2F/2F mice lack carotid body and exhibit abnormalities of the superior cervical sympathetic ganglion and carotid sinus nerve

(2008) Yoko Kameda et al.   DEVELOPMENTAL BIOLOGY