Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides

Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism

(2017) Rongkun Tao et al.   NATURE METHODS

Metabolic Control of Longevity

(2016) Carlos López-Otín et al.   CELL

Apollo-NADP+: a spectrally tunable family of genetically encoded sensors for NADP+

(2016) William D Cameron et al.   NATURE METHODS

Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds

(2016) Michael S. Bonkowski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

NAD+ salvage pathway in cancer metabolism and therapy

(2016) Barry E. Kennedy et al.   PHARMACOLOGICAL RESEARCH

Biosensor reveals multiple sources for mitochondrial NAD+

(2016) X. A. Cambronne et al.   SCIENCE

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

(2016) H. Zhang et al.   SCIENCE

SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents

(2015) Yuzheng Zhao et al.   Cell Metabolism

NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

(2015) Carles Cantó et al.   Cell Metabolism

Acute Activation of Oxidative Pentose Phosphate Pathway as First-Line Response to Oxidative Stress in Human Skin Cells

(2015) Andreas Kuehne et al.   MOLECULAR CELL

NAD+ in aging, metabolism, and neurodegeneration

(2015) E. Verdin   SCIENCE

Determination of the Cytosolic NADPH/NADP Ratio in Saccharomyces cerevisiae using Shikimate Dehydrogenase as Sensor Reaction

(2015) Jinrui Zhang et al.   Scientific Reports

Bioluminescent Cell-Based NAD(P)/NAD(P)H Assays for Rapid Dinucleotide Measurement and Inhibitor Screening

(2014) Jolanta Vidugiriene et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Metformin: From Mechanisms of Action to Therapies

(2014) Marc Foretz et al.   Cell Metabolism

Components and regulation of nuclear transport processes

(2014) Bastien Cautain et al.   FEBS Journal

Caloric restriction mimetics: towards a molecular definition

(2014) Frank Madeo et al.   NATURE REVIEWS DRUG DISCOVERY

The pentose phosphate pathway and cancer

(2014) Krushna C. Patra et al.   TRENDS IN BIOCHEMICAL SCIENCES

Method for Accurate Determination of Dissociation Constants of Optical Ratiometric Systems: Chemical Probes, Genetically Encoded Sensors, and Interacting Molecules

(2013) Adam Pomorski et al.   ANALYTICAL CHEMISTRY

The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

(2013) Laurent Mouchiroud et al.   CELL

Mitonuclear protein imbalance as a conserved longevity mechanism

(2013) Riekelt H. Houtkooper et al.   NATURE

A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins

(2013) Gražvydas Lukinavičius et al.   Nature Chemistry

Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice

(2013) C. B. Peek et al.   SCIENCE

The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

(2012) Carles Cantó et al.   Cell Metabolism

A Fluorescent Sensor for GABA and Synthetic GABAB Receptor Ligands

(2012) Anastasiya Masharina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Exploiting Ligand-Protein Conjugates to Monitor Ligand-Receptor Interactions

(2012) Hirohito Haruki et al.   PLoS One

Imaging Cytosolic NADH-NAD+ Redox State with a Genetically Encoded Fluorescent Biosensor

(2011) Yin Pun Hung et al.   Cell Metabolism

Genetically Encoded Fluorescent Sensors for Intracellular NADH Detection

(2011) Yuzheng Zhao et al.   Cell Metabolism

Semisynthesis of Fluorescent Metabolite Sensors on Cell Surfaces

(2011) Matthias A. Brun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The quantitative proteome of a human cell line

(2011) M. Beck et al.   Molecular Systems Biology

A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis

(2011) Christopher Chidley et al.   Nature Chemical Biology

Calorie Restriction: Is AMPK a Key Sensor and Effector?

(2011) Carles Cantó et al.   PHYSIOLOGY

Classification of the short-chain dehydrogenase/reductase superfamily using hidden Markov models

(2010) Yvonne Kallberg et al.   FEBS Journal

Organelle-Targetable Fluorescent Probes for Imaging Hydrogen Peroxide in Living Cells via SNAP-Tag Protein Labeling

(2010) Duangkhae Srikun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Importing Mitochondrial Proteins: Machineries and Mechanisms

(2009) Agnieszka Chacinska et al.   CELL

AMP-Activated Protein Kinase-Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

(2009) J.-H. Um et al.   DIABETES

Semisynthetic Fluorescent Sensor Proteins Based on Self-Labeling Protein Tags

(2009) Matthias A. Brun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

(2008) Georgyi V. Los et al.   ACS Chemical Biology