Article
Chemistry, Applied
Likun Duan, Yan Zhao
Summary: A thiourea-based fluorescent functional monomer was used in this study to synthesize molecularly imprinted nanoparticle sensors for NSAIDs, achieving micromolar binding affinities and comparable selectivities to polyclonal antibodies. The sensors had a detection limit of around 50 ng/mL in aqueous solution, with negligible interference from common carboxylic acids.
REACTIVE & FUNCTIONAL POLYMERS
(2021)
Article
Chemistry, Multidisciplinary
Xin Zhang, Bo Tang, Yansong Li, Chengbin Liu, Pengfei Jiao, Yuping Wei
Summary: A new strategy for designing molecularly imprinted magnetic fluorescent nanocomposites for selective fluorescence detection of target proteins has been proposed. The multifunctional nanocomposite with optics, magnetism, and biocompatibility has shown promising results in the detection of lysozyme in biological samples.
Review
Chemistry, Multidisciplinary
Shuxin Xu, Lisheng Wang, Zhen Liu
Summary: Molecularly imprinted polymers (MIPs) are tailor-made affinity materials with unique binding cavities, which have been engineered for cancer therapy. Using nanoMIPs as alternatives to current nanomaterials offers potential solutions to existing challenges in biological ligand-based nanomedicines.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Biophysics
Danyang Zhao, Yao Zhang, Shaowei Ji, Yao Lu, Xinyu Bai, Mengting Yin, Chusen Huang, Nengqin Jia
Summary: The proposed highly sensitive quenching molecular imprinting photoelectrochemical sensor demonstrates efficient detection of acrylamide with excellent specificity, sensitivity, and stability, making it suitable for monitoring potential risks in food samples.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Shiting Zhang, Zhiqiang Liu, Siyu Jin, Yufei Bai, Xingjia Feng, Guoqi Fu
Summary: Epitope imprinting on sacrificial asymmetric template-modified Janus nanocores is a promising approach for fabricating oriented surface epitope-imprinted open-mouthed polymer nanocapsules. The resulting OM-MIP NCs show fast fluorescence response and excellent target protein detection performance.
Article
Chemistry, Multidisciplinary
Zikuan Gu, Yueru Dong, Shuxin Xu, Lisheng Wang, Zhen Liu
Summary: This study presents a smart prodrug delivery system based on molecularly imprinted polymers (MIPs) for specific accumulation and gradual release of drugs at tumor sites. In contrast to traditional prodrug designs, this system is liver-independent and relies on tumor environments for drug release.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Applied
Wenting Zhu, Yushun Zhou, Shuai Liu, Mei Luo, Jun Du, Jieping Fan, Hua Xiong, Hailong Peng
Summary: In this study, a dual-recognition sensor (MF-MIPs) was developed for highly selective and sensitive detection of 4-nitrophenol in food samples using surface imprinting, magnetic separation, and fluorescent detection. The sensor showed good linear response, low detection limit, high anti-interference capability, excellent stability, and reusability. This method may be a promising approach for 4-NP detection in food samples.
Article
Chemistry, Analytical
Jiasheng Xu, Meng Shang, Juan Liu, Xin Chen, Yuhua Cao
Summary: A colorimetric sensor for bisphenol A (BPA) based on magnetically responsive photonic crystals was developed using molecularly imprinted magnetic colloidal nanoparticles (MIMCNPs) as blocking units. The sensor showed high sensitivity, good selectivity, rapid response, renewability, and easy operation. The structural color of the sensor changed from green to red as BPA concentration increased, with a detection limit estimated at 0.001 g/L and imprint factor of 4.29.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Fatemeh Parnianchi, Soheila Kashanian, Maryam Nazari, Carlo Santoro, Paolo Bollella, Kambiz Varmira
Summary: The study developed a method using MIP to selectively activate bilirubin, and for the first time measured the BR content in saliva. By electrode modification with multi-walled carbon nanotubes and electropolymerization, a highly selective and sensitive electrochemical sensor was successfully prepared.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Kaseb Alanazi, Alvaro Garcia Cruz, Sabrina Di Masi, Annelies Voorhaar, Omar Sheej Ahmad, Todd Cowen, Elena Piletska, Nigel Langford, Timothy J. Coats, Mark R. Sims, Sergey A. Piletsky
Summary: A highly sensitive disposable electrochemical sensor for paracetamol was developed using nanoMIPs, showing good detection performance in human plasma with high selectivity.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Lingyun Wang, Kunsong Liang, Wenbao Feng, Chunyan Chen, Hang Gong, Changqun Cai
Summary: A novel fluorescent MIPs sensor based on MOF was successfully prepared for the detection of HAV with excellent selectivity and high sensitivity. This method is simple and rapid, capable of detecting viruses within 15 minutes and maintaining high selectivity in the presence of HAV.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Applied
Christine Unger, Peter A. Lieberzeit
Summary: Molecularly imprinted polymers show potential in replacing biological recognition species, such as antibodies, in sensing applications. However, challenges remain in generating surface imprints, increasing binding capacity, and selectivity.
REACTIVE & FUNCTIONAL POLYMERS
(2021)
Review
Chemistry, Multidisciplinary
Xiaotong Yao
Summary: Acids and anions are widely distributed in plants, animals and biotechnological products, and their detection is of great importance. Molecular imprinting technology can achieve high sensitivity and selectivity for the detection of acids and anions, with fluorescent molecularly imprinted polymers considered as promising candidates.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Article
Environmental Sciences
Ming Guo, Yinglu Hu, Rui Wang, Hongwei Yu, Liping Sun
Summary: ZnO quantum dots were synthesized and CuFe2O4 nanoparticles were prepared to fabricate ZnO/CuFe2O4 composites, followed by the production of a specific molecule recognition photocatalyst (ZCF@MB-MIP) using methylene blue as the template molecule. The ZCF@MB-MIP showed efficient photocatalytic degradation of methylene blue under natural light, with a degradation rate of 95.8%.
ENVIRONMENTAL RESEARCH
(2021)
Review
Chemistry, Multidisciplinary
Xiaotong Yao
Summary: This paper presents the application of fluorescent molecularly imprinted polymers (fMIPs) in the detection of acids and anions. By creating template-tailored cavities, this technique enables high sensitivity and selectivity in detection. Fluorescent molecularly imprinted polymers have gained attention due to their high sensitivity and ease of operation.
ARABIAN JOURNAL OF CHEMISTRY
(2022)