CRISPR-Cas antimicrobials: Challenges and future prospects

Exploring the potential of genome editing CRISPR-Cas9 technology

(2017) Vijai Singh et al.   GENE

To the G20: incentivising antibacterial research and development

(2017) Christine Årdal et al.   LANCET INFECTIOUS DISEASES

Rules of the road for insect gene drive research and testing

(2017) Zach Adelman et al.   NATURE BIOTECHNOLOGY

Anti-CRISPR: discovery, mechanism and function

(2017) April Pawluk et al.   NATURE REVIEWS MICROBIOLOGY

CRISPR-Cpf1 assisted genome editing of Corynebacterium glutamicum

(2017) Yu Jiang et al.   Nature Communications

The Discovery, Mechanisms, and Evolutionary Impact of Anti-CRISPRs

(2017) Adair L. Borges et al.   Annual Review of Virology

Scaffolding bacterial genomes and probing host-virus interactions in gut microbiome by proximity ligation (chromosome capture) assay

(2017) Martial Marbouty et al.   Science Advances

Naturally Occurring Off-Switches for CRISPR-Cas9

(2016) April Pawluk et al.   CELL

Evolution of Resistance Against CRISPR/Cas9 Gene Drive

(2016) Robert L. Unckless et al.   GENETICS

CRISPR/Cas9-Mediated Re-Sensitization of Antibiotic-Resistant Escherichia coli Harboring Extended-Spectrum ��-Lactamases

(2016) Jun-Seob Kim et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Genetically Engineered Phages: a Review of Advances over the Last Decade

(2016) Diana P. Pires et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The diversity-generating benefits of a prokaryotic adaptive immune system

(2016) Stineke van Houte et al.   NATURE

Achieving global targets for antimicrobial resistance

(2016) R. Laxminarayan et al.   SCIENCE

Evolution of Resistance Against CRISPR/Cas9 Gene Drive

(2016) Robert L. Unckless et al.   GENETICS

Inactivation of CRISPR-Cas systems by anti-CRISPR proteins in diverse bacterial species

(2016) April Pawluk et al.   Nature Microbiology

Parallel Compensatory Evolution Stabilizes Plasmids across the Parasitism-Mutualism Continuum

(2015) Ellie Harrison et al.   CURRENT BIOLOGY

Massively parallel sequencing of single cells by epicPCR links functional genes with phylogenetic markers

(2015) Sarah J Spencer et al.   ISME Journal

An updated evolutionary classification of CRISPR–Cas systems

(2015) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

Temperate and lytic bacteriophages programmed to sensitize and kill antibiotic-resistant bacteria

(2015) Ido Yosef et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases

(2014) Robert J Citorik et al.   NATURE BIOTECHNOLOGY

Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials

(2014) David Bikard et al.   NATURE BIOTECHNOLOGY

Programmable Removal of Bacterial Strains by Use of Genome-Targeting CRISPR-Cas Systems

(2014) A. A. Gomaa et al.   mBio

Metatranscriptomics of the Human Oral Microbiome during Health and Disease

(2014) P. Jorth et al.   mBio

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

(2014) Casey M. Theriot et al.   Nature Communications

Cytotoxic Chromosomal Targeting by CRISPR/Cas Systems Can Reshape Bacterial Genomes and Expel or Remodel Pathogenicity Islands

(2013) Reuben B. Vercoe et al.   PLoS Genetics

Dealing with the Evolutionary Downside of CRISPR Immunity: Bacteria and Beneficial Plasmids

(2013) Wenyan Jiang et al.   PLoS Genetics

CRISPR Interference Can Prevent Natural Transformation and Virulence Acquisition during In Vivo Bacterial Infection

(2012) David Bikard et al.   Cell Host & Microbe

Functional Characterization of the Antibiotic Resistance Reservoir in the Human Microflora

(2009) M. O. A. Sommer et al.   SCIENCE

Adaptive Plasmid Evolution Results in Host-Range Expansion of a Broad-Host-Range Plasmid

(2008) L. De Gelder et al.   GENETICS