Article
Urology & Nephrology
Anne M. Suskind, Shoujun Zhao, W. John Boscardin, Kenneth Covinsky, Emily Finlayson
Summary: The study compared short and long-term outcomes of nursing home residents and community dwelling older adults undergoing surgery for pelvic organ prolapse. Despite matching on several characteristics, nursing home residents showed increased risk of longer hospital stay, complications, and mortality compared to community dwelling older adults, suggesting additional vulnerabilities contributing to surgical risk in this population.
JOURNAL OF UROLOGY
(2021)
Article
Nursing
Ling-Na Kong, Qiong Lyu, Hai-Yan Yao, Li Yang, Shuo-Zhen Chen
Summary: Frailty and prefrailty are common among community-dwelling older adults with diabetes, with frailty being more prevalent in females and unmarried individuals. Studies using Frailty Phenotype definition and conducted in Asia showed lower prevalence of frailty.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2021)
Article
Geriatrics & Gerontology
Lixing Zhou, Hui Shi, Rui Cheng, Meiling Ge, Fengjuan Hu, Lisha Hou, Xin Xia, Xiaolei Liu, Yixin Liu, Yunli Zhao, Linghui Deng, Wanyu Zhao, Zhiliang Zuo, Xuelian Sun, Jirong Yue, Birong Dong
Summary: This study identified a potential association between pTau and frailty in older adults. Further research should monitor the longitudinal trajectory of pTau changes in frail individuals and investigate the molecular mechanisms involved.
Article
Geriatrics & Gerontology
Shelda Sajeev, Stephanie Champion, Anthony Maeder, Susan Gordon
Summary: This study utilized machine learning methods to identify factors contributing to the early trajectory from good health to pre-frailty in middle aged and older adults. Physiological, social, and lifestyle variables were found to be associated with pre-frailty outcomes. Machine learning models indicated that high BMI, low muscle mass, poor grip strength and balance, emotional distress, poor sleep quality were linked to pre-frailty.
Review
Nursing
Yiming Qiu, Guichen Li, Xinxin Wang, Lufang Zheng, Cong Wang, Chunyan Wang, Li Chen
Summary: This study investigated the pooled prevalence of cognitive frailty among community-dwelling older adults, with the overall prevalence found to be 9%. The prevalence of cognitive frailty was higher in older women, and there has been an increase in prevalence in recent years.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2022)
Article
Geriatrics & Gerontology
Ki-Soo Park, Gyeong-Ye Lee, Young-Mi Seo, Sung-Hyo Seo, Jun-Il Yoo
Summary: The study aimed to investigate the prevalence of osteosarcopenia in the over 60-year-old community and found that osteosarcopenia is a relatively common disease group in older adults, which may lead to deterioration of health outcomes. Therefore, management of both osteopenia and sarcopenia in older adults should occur together.
Review
Public, Environmental & Occupational Health
Qi Zhou, Yao Li, Qiang Gao, Huiping Yuan, Liang Sun, Huan Xi, Wenbin Wu
Summary: This study systematically reviewed the epidemiology of frailty in China and found that the overall prevalence of frailty and prefrailty among older community dwellers was 10.1% and 43.9%, respectively. It also identified subgroups at higher risk of frailty, such as women, older adults over 70 years, unmarried individuals, those living alone, and those with lower education. The study recommends that the Chinese government pay more attention to these high-risk groups and regions with a high prevalence of frailty.
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Priya Saravanakumar, Arun Balachandran, T. Muhammad, Drishti Drishti, Shobhit Srivastava
Summary: This study investigates the wealth-based inequalities in physical frailty in India and quantifies the contributions of potential predictors to this inequality using data from the Longitudinal Ageing Study in India (LASI). Results show significant disparities in physical frailty between the poor and non-poor groups, with factors such as body mass index, wealth index, educational status, and region contributing significantly to these inequalities.
Article
Geriatrics & Gerontology
Li Feng Tan, Yiong Huak Chan, Reshma A. Merchant
Summary: This study evaluated the dentition status, frailty, and cognitive impairment among community-dwelling older adults. The findings showed that having teeth was associated with lower risk of cognitive impairment and higher likelihood of being robust or pre-frail compared to being edentulous. The study highlights the importance of population-level screening for oral health, frailty, and cognitive impairment as modifiable risk factors for healthy aging.
Article
Multidisciplinary Sciences
Shahram Oveisgharan, Lei Yu, David A. Bennett, Aron S. Buchman
Summary: This study explored the transition from no motor impairment to mobility disability and parkinsonism in older adults and their associations with death. It found that mobility disability was more common than parkinsonism, and individuals with both impairments had a greater risk of death. The order in which impairments occurred did not affect the risk of death. Further research is needed to understand the underlying biology of these transitions and their impact on survival.
Article
Geriatrics & Gerontology
Yanxia Lu, Crystal Tze Ying Tan, Xinyi Gwee, Keng Bee Yap, Tamas Fulop, Fang Pan, Anis Larbi, Tze Pin Ng
Summary: The study found that a high pathogen load is associated with gait speed, functional mobility, cognitive function, and frailty index, as well as with inflammatory biomarker levels. Blood biomarkers did not fully explain the observed association between pathogen load and functional aging measures.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Article
Geriatrics & Gerontology
Takehiko Doi, Sho Nakakubo, Kota Tsutsumimoto, Satoshi Kurita, Hideaki Ishii, Hiroyuki Shimada
Summary: Gait is a valuable measure of physical function in older adults, with slower gait speed, shorter stride length, lower cadence, and higher stride length variability being associated with increased mortality risk. Participants with low function in all gait variables had higher mortality risk, and the risk increased with the number of variables showing low gait function compared to normal gait function. Multifaceted gait analysis may be useful for evaluating mortality risk.
Article
Geriatrics & Gerontology
Yunhwan Lee, Eunsaem Kim, Jihye Yun, Kumban Walter Chuck
Summary: Frailty in older adults, especially when combined with other health domains such as cognitive, psychological, and social aspects, can predict adverse outcomes including institutionalization and mortality. The risk of negative health outcomes increases with frailty in a higher number of domains, and specific combinations of frailty domains have varying effects on outcomes.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Review
Nutrition & Dietetics
Yue-Heng Yin, Justina Yat Wa Liu, Tsz Man Fan, Kit Man Leung, Man Wai Ng, Tsun Yee Tsang, Ka Po Wong, Maritta Valimaki
Summary: Nutritional advice is more effective than exercise in reducing body weight and fat mass in frail, obese older adults, as well as enhancing physical function and psychosocial well-being. However, it is less effective in increasing muscle strength and preventing lean mass loss compared to exercise or combined interventions.
FRONTIERS IN NUTRITION
(2021)
Article
Geriatrics & Gerontology
Chikako Tange, Yukiko Nishita, Makiko Tomida, Rei Otsuka, Fujiko Ando, Hiroshi Shimokata, Hidenori Arai
Summary: This study used group-based multitrajectory modeling to identify trajectories of 5 frailty assessment components and determined distinctive frailty trajectory groups. The results showed that some individuals remained robust, while others primarily experienced physical mobility decline and progressed into frailty. Providing interventions according to the characteristics of each group may be beneficial.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Letter
Geriatrics & Gerontology
Gotaro Kojima
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2019)
Letter
Geriatrics & Gerontology
Gotaro Kojima, Yu Taniguchi, Steve Iliffe, Tomohiko Urano, Kate Walters
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2019)
Review
Geriatrics & Gerontology
Gotaro Kojima
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2019)
Review
Geriatrics & Gerontology
Gotaro Kojima, Kate Walters, Steve Iliffe, Yu Taniguchi, Nanako Tamiya
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2020)
Review
Cell Biology
Gotaro Kojima, Yu Taniguchi, Akihiko Kitamura, Yoshinori Fujiwara
AGEING RESEARCH REVIEWS
(2020)
Article
Geriatrics & Gerontology
Gotaro Kojima, Kohei Ogawa, Steve Iliffe, Yu Taniguchi, Kate Walters
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2020)
Article
Nutrition & Dietetics
Gotaro Kojima, Steve Iliffe, Stephen Jivraj, Kate Walters
Article
Geriatrics & Gerontology
Gotaro Kojima, Yu Taniguchi, Reijiro Aoyama, Tomohiko Urano
Summary: Earlier menopause is significantly associated with a higher risk of developing frailty, while later menopause does not have an impact. This suggests that menopause and its related factors may play an important role in the sex difference in frailty.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2022)
Review
Immunology
Yuji Yamada, Takaaki Kobayashi, Angela Condo, Aroonsiri Sangarlangkarn, Fred Ko, Yu Taniguchi, Gotaro Kojima
Summary: The systematic review identified a variation in frailty prevalence among individuals aged 50 or older with HIV. The meta-analysis results showed that the overall prevalence of frailty and prefrailty in this population was 10.9% and 47.2% respectively. Frailty is a clinically recognized state associated with disability, hospitalization, and mortality. Effective strategies for frailty screening and intervention are needed for this vulnerable population.
OPEN FORUM INFECTIOUS DISEASES
(2022)
Letter
Geriatrics & Gerontology
Gotaro Kojima, Reijiro Aoyama, Marianne Tanabe
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Medicine, General & Internal
Akash Raut, Anjila Thapa, Ashish Shrestha, Kamal Saud, Reema Rajbhandari, Shailendra Katwal
Summary: Although sporadic Creutzfeldt-Jakob disease is rare and challenging to diagnose early, meticulous clinical examination, electroencephalography, and neuroimaging findings can aid in diagnosis.
CLINICAL CASE REPORTS
(2022)
Review
Cell Biology
Gotaro Kojima, Yu Taniguchi, Reijiro Aoyama, Marianne Tanabe
Summary: This study provides quantitative evidence through systematic review and meta-analysis on the significant associations between loneliness and frailty in community-dwelling older adults, both in cross-sectional and longitudinal studies.
AGEING RESEARCH REVIEWS
(2022)
Review
Geriatrics & Gerontology
Gotaro Kojima, Yu Taniguchi, Kohei Ogawa, Reijiro Aoyama, Tomohiko Urano
Summary: This systematic review and meta-analysis found that later age at menopause is significantly associated with a lower risk of prevalent frailty. These findings can provide useful information for clinicians in evaluating and stratifying frailty risk in postmenopausal women.
Review
Multidisciplinary Sciences
Gotaro Kojima, Yu Taniguchi, Masanori Iwasaki, Reijiro Aoyama, Tomohiko Urano
Summary: Oral health is crucial for overall health and well-being. Mastication, an important oral function, may deteriorate with age. The existing evidence on the association between masticatory dysfunction and frailty is limited and inconclusive.
Review
Geriatrics & Gerontology
Gotaro Kojima, Reijiro Aoyama, Yu Taniguchi