Synaptic dysfunction in complex psychiatric disorders: from genetics to mechanisms

DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis

(2017) Fei Ye et al.   NEURON

Rare genetic variants in CX3CR1 and their contribution to the increased risk of schizophrenia and autism spectrum disorders

(2017) K Ishizuka et al.   Translational Psychiatry

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

(2016) Hansen Lui et al.   CELL

Altered proliferation and networks in neural cells derived from idiopathic autistic individuals

(2016) M C Marchetto et al.   MOLECULAR PSYCHIATRY

Deficient autophagy in microglia impairs synaptic pruning and causes social behavioral defects

(2016) H-J Kim et al.   MOLECULAR PSYCHIATRY

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders

(2015) Jessica Mariani et al.   CELL

Synaptic dysregulation in a human iPS cell model of mental disorders

(2014) Zhexing Wen et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Modelling schizophrenia using human induced pluripotent stem cells

(2011) Kristen J. Brennand et al.   NATURE

Extraordinary neoteny of synaptic spines in the human prefrontal cortex

(2011) Zdravko Petanjek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA