Inhibiting RIPK1 Limits Neuroinflammation and Alleviates Postoperative Cognitive Impairments in D-Galactose-Induced Aged Mice

Role of D-galactose-induced brain aging and its potential used for therapeutic interventions

(2018) Thazin Shwe et al.   EXPERIMENTAL GERONTOLOGY

Post-Operative Cognitive Dysfunction: An exploration of the inflammatory hypothesis and novel therapies

(2018) David R. Skvarc et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

RIP1-RIP3-DRP1 pathway regulates NLRP3 inflammasome activation following subarachnoid hemorrhage

(2017) Keren Zhou et al.   EXPERIMENTAL NEUROLOGY

Activation of cannabinoid receptor type 2 attenuates surgery-induced cognitive impairment in mice through anti-inflammatory activity

(2017) Lingling Sun et al.   Journal of Neuroinflammation

Necroptosis activation in Alzheimer's disease

(2017) Antonella Caccamo et al.   NATURE NEUROSCIENCE

The C-terminal tails of endogenous GluA1 and GluA2 differentially contribute to hippocampal synaptic plasticity and learning

(2017) Zikai Zhou et al.   NATURE NEUROSCIENCE

Pre-existing weakness is critical for the occurrence of postoperative cognitive dysfunction in mice of the same age

(2017) Yujie Tang et al.   PLoS One

RIPK1 promotes inflammation and β-amyloid accumulation in Alzheimer’s disease

(2017) David C. Rubinsztein   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIPK1 mediates a disease-associated microglial response in Alzheimer’s disease

(2017) Dimitry Ofengeim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sepsis-induced selective loss of NMDA receptors modulates hippocampal neuropathology in surviving septic mice

(2017) Shuibing Zhang et al.   PLoS One

Pathological changes of the hippocampus and cognitive dysfunction following frontal lobe surgery in a rat model

(2016) Santiago Hem et al.   ACTA NEUROCHIRURGICA

Nec‐1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS1 mice

(2016) Seung‐Hoon Yang et al.   EMBO Molecular Medicine

Activated brain mast cells contribute to postoperative cognitive dysfunction by evoking microglia activation and neuronal apoptosis

(2016) Xiang Zhang et al.   Journal of Neuroinflammation

Necroptosis in development, inflammation and disease

(2016) Ricardo Weinlich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lasting impact of general anaesthesia on the brain: mechanisms and relevance

(2016) Laszlo Vutskits et al.   NATURE REVIEWS NEUROSCIENCE

Systemic HMGB1 Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats

(2016) Niccolò Terrando et al.   Frontiers in Immunology

α5GABAAreceptor deficiency causes autism-like behaviors

(2016) Agnieszka A. Zurek et al.   Annals of Clinical and Translational Neurology

Upregulation of the receptor-interacting protein 3 expression and involvement in neural tissue damage after spinal cord injury in mice

(2015) Haruo Kanno et al.   BMC NEUROSCIENCE

Inhibiting tumor necrosis factor-α signaling attenuates postoperative cognitive dysfunction in aged rats

(2015) YUANZHONG MA et al.   Molecular Medicine Reports

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

The diverse role of RIP kinases in necroptosis and inflammation

(2015) John Silke et al.   NATURE IMMUNOLOGY

Aging Differentially Affects the Loss of Neuronal Dendritic Spine, Neuroinflammation and Memory Impairment at Rats after Surgery

(2014) Yuan Le et al.   PLoS One

Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice

(2014) Zhipeng Xu et al.   Scientific Reports

Necroptosis in Immunity and Ischemia-Reperfusion Injury

(2013) A. Linkermann et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Surgical Incision-Induced Nociception Causes Cognitive Impairment and Reduction in Synaptic NMDA Receptor 2B in Mice

(2013) X. Zhang et al.   JOURNAL OF NEUROSCIENCE

Pyrrolidine dithiocarbamate attenuates surgery-induced neuroinflammation and cognitive dysfunction possibly via inhibition of nuclear factor κB

(2013) J. Zhang et al.   NEUROSCIENCE

Intracisternal Interleukin-1 Receptor Antagonist Prevents Postoperative Cognitive Decline and Neuroinflammatory Response in Aged Rats

(2012) R. M. Barrientos et al.   JOURNAL OF NEUROSCIENCE

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Tumor necrosis factor-  triggers a cytokine cascade yielding postoperative cognitive decline

(2010) N. Terrando et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA