Review
Chemistry, Medicinal
Sumeer Brar, Carolyn Haugh, Nicole Robertson, Patrick Mbullo Owuor, Carrie Waterman, George J. Fuchs, Suzanna Labib Attia
Summary: Moringa leaf supplementation has a positive impact on improving childhood anemia, vitamin A deficiency, underweight, and increasing breastmilk production.
PHYTOTHERAPY RESEARCH
(2022)
Article
Obstetrics & Gynecology
Abigail Liberty, Elizabeth S. Rubin, Kimberley A. Bullard, Katherine Au
Summary: Lactation is a powerful tool for improving health trajectories and promoting reproductive justice. Various human milk-expression technologies, including pumps and accessories, can help patients establish and maintain breastfeeding. Understanding and counseling patients about these technologies is important for physicians in supporting patients' feeding goals.
OBSTETRICS AND GYNECOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Hernan D. Laviano, Gerardo Gomez, Maria Munoz, Juan M. Garcia-Casco, Yolanda Nunez, Rosa Escudero, Ana Heras Molina, Antonio Gonzalez-Bulnes, Cristina Ovilo, Clemente Lopez-Bote, Ana I. Rey
Summary: Modifying the composition of a sow's milk, specifically by supplementing with vitamin E and/or hydroxytyrosol, can improve the intestinal health and growth of piglets. The study found that vitamin E supplementation increased the levels of C18:1n-7 in colostrum, while hydroxytyrosol increased the levels of polyunsaturated fatty acids. Vitamin E supplementation also decreased certain fatty acids and increased ?-6-desaturase activity in 7-day milk. The lowest levels of milk lipid oxidation were observed in the vitamin E supplemented group, while hydroxytyrosol supplementation increased oxidation.
Review
Microbiology
Sophie I. S. Wedekind, Natalie S. Shenker
Summary: Humans have always coexisted with viruses, and evolutionary pressure has shaped the intrinsic properties of lactation and milk to support the neonate's immune system and protect against pathogens. Human milk contains specific components that support immune learning and maturation, as well as provide direct protection against microorganisms. However, there is a lack of awareness among the public and healthcare professionals about the specific antiviral properties of human milk beyond the production of maternal antibodies.
Review
Nutrition & Dietetics
Buket Soyyilmaz, Marta Hanna Miks, Christoph Hermann Rohrig, Martin Matwiejuk, Agnes Meszaros-Matwiejuk, Louise Kristine Vigsnaes
Summary: Human milk oligosaccharides (HMOs) are complex carbohydrates abundant in human milk, with over 200 different structures identified. The concentrations of HMOs in breast milk vary according to lactation period and mother's genetic status. Studies have shown significant variations in HMO concentrations for different types across lactation stages. In mature pooled human milk, the top 15 individual HMOs make up the majority of total HMO concentration.
Article
Nutrition & Dietetics
Jelisa Gallant, Kathleen Chan, Tim J. Green, Frank T. Wieringa, Shalem Leemaqz, Rem Ngik, Jeffrey R. Measelle, Dare A. Baldwin, Mam Borath, Prak Sophonneary, Lisa N. Yelland, Daniela Hampel, Setareh Shahab-Ferdows, Lindsay H. Allen, Kerry S. Jones, Albert Koulman, Damon A. Parkington, Sarah R. Meadows, Hou Kroeun, Kyly C. Whitfield
Summary: This study found that a daily thiamine dose of 2.35 mg was needed to reach a total thiamine concentration of 191 μg/L in human milk. A dose of 1.2 mg/day for 22 weeks was sufficient to increase milk thiamine concentrations to levels similar to higher supplementation doses (2.4 and 10 mg/day), and comparable to healthy mothers in regions without beriberi.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Agriculture, Dairy & Animal Science
M. B. Poindexter, R. Zimpel, A. Vieira-Neto, A. Husnain, A. C. M. Silva, A. Faccenda, A. Sanches de Avila, P. Celi, C. Cortinhas, J. E. P. Santos, C. D. Nelson
Summary: The objectives of this experiment were to determine the effects of supplementing 25-hydroxyvitamin D3 compared with vitamin D3 at 1 or 3 mg/d in late gestation on production outcomes of dairy cows. The results showed that feeding 25-hydroxyvitamin D3 increased colostrum and milk yield compared to vitamin D3. The effect of 25-hydroxyvitamin D3 on milk yield may be related to serum calcium concentrations.
JOURNAL OF DAIRY SCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Angela Feiner Solis, Ana Avedillo Salas, Maria Jose Luesma Bartolome, Sonia Santander Ballestin
Summary: This systematic review examines the impact of vitamin D supplementation on the disease course of COVID-19. The results suggest that regardless of initial vitamin D serum levels, patients benefit from vitamin D supplementation, although the outcomes are inconsistent and larger clinical trials are needed for confirmation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Na Li, Qinggang Xie, Lina Zhao, Jialu Shi, Smith Etareri Evivie, Xiuli Lv, Guicheng Huo, Bailiang Li
Summary: The study showed that human milk is more effective than infant formula in improving the intestinal microbiota and immune system of infants. Human milk decreased levels of alanine transaminase, alkaline phosphatase, and total protein, while also reducing intestinal mucosal permeability. The findings provide a theoretical basis for the development of infant formulas.
Article
Public, Environmental & Occupational Health
Huan Liu, Qixiong Chen, Linchao Yu, Ting Yang, Jie Chen, Jingkun Miao, Tingyu Li
Summary: The study found that vitamin A levels in healthy infants increased significantly with age, even without additional supplementation. The percentage of infants with low vitamin A levels decreased from birth to 6 months. No infants showed clinical signs of vitamin A deficiency during the follow-up period.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Nutrition & Dietetics
Monia Kittana, Asma Ahmadani, Lily Stojanovska, Amita Attlee
Summary: Children with autism spectrum disorder (ASD) have lower vitamin D levels and the deficiency is strongly correlated with ASD severity. Vitamin D supplementation can significantly reduce ASD severity, but the effect may vary between treatment and control groups. Variations in vitamin D dose protocols and concurrent interventions may contribute to the variability of results. The age of introducing vitamin D intervention may also affect the effectiveness of treatment. Further long-term, well-designed randomized controlled trials are needed to confirm the impact of vitamin D on severity in children with ASD.
Review
Health Care Sciences & Services
George Dahma, Gowry Reddy, Marius Craina, Catalin Dumitru, Alin Popescu, Lavinia Stelea, Radu Neamtu, Adrian Gluhovschi, Razvan Nitu, Anca Laura Maghiari, Gianina Tapalaga, Diana Aurora Arnautu, Aditya Nelluri, Ram Kiran Maganti, Elena Bernad
Summary: Early pregnancy vitamin D supplementation may reduce the risk of preeclampsia, but further research is needed to determine the optimal supplementation strategy and clarify the relationship between vitamin D and preeclampsia risk, considering the inconsistencies in dosage, timing, and methodological differences between studies.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Nutrition & Dietetics
Caroline Thum, Clare Wall, Li Day, Ignatius M. Y. Szeto, Fang Li, Yalu Yan, Matthew P. G. Barnett
Summary: This article reviews studies on the composition of human milk fat globule (MFG) components over the course of lactation. It discusses the changes in concentrations of phospholipids, gangliosides, cholesterol, fatty acids and proteins and their potential implications for infant health. The article also highlights factors such as maternal diet and geographical location that can influence MFG composition.
FRONTIERS IN NUTRITION
(2022)
Article
Public, Environmental & Occupational Health
Dongqing Wang, Uma Chandra Mouli Natchu, Anne Marie Darling, Ramadhani A. Noor, Ellen Hertzmark, Willy Urassa, Wafaie W. Fawzi
Summary: While prenatal MMS showed modest improvements in weight and length z-scores in the first 6 months of life, it did not have lasting effects. Prenatal or postnatal MMS did not show significant benefits for other child outcomes.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Review
Immunology
Yanrui Wu, Chuan Liu, Weiguo Dong
Summary: Growing evidence suggests that micronutrient status may affect the course of inflammatory bowel disease (IBD), but deficiencies are often overlooked during treatment. Studies have focused on vitamin D and iron supplementation, but research on other vitamins and minerals is still limited. This review provides an overview of the therapeutic effects of micronutrient supplementation in IBD, aiming to draw attention to monitoring and supplementation in IBD patients and provide perspectives for future research.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Nutrition & Dietetics
Chong-Su Kim
Summary: The gut microbiota plays a crucial role in brain function through the gut-brain axis. This review highlights the effects of gut microbiota-derived dietary metabolites on cell-to-cell interactions in the central nervous system, particularly microglia, astrocytes, and neuronal cells, affecting cognitive function, mood, and behavior. The review also discusses the potential of diet-induced microbial metabolite-based therapies as novel approaches to mental health treatment.
ADVANCES IN NUTRITION
(2024)