Radiosensitization Effect of Talazoparib, a Parp Inhibitor, on Glioblastoma Stem Cells Exposed to Low and High Linear Energy Transfer Radiation
出版年份 2018 全文链接
标题
Radiosensitization Effect of Talazoparib, a Parp Inhibitor, on Glioblastoma Stem Cells Exposed to Low and High Linear Energy Transfer Radiation
作者
关键词
-
出版物
Scientific Reports
Volume 8, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-02-21
DOI
10.1038/s41598-018-22022-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Restricted Delivery of Talazoparib Across the Blood–Brain Barrier Limits the Sensitizing Effects of PARP Inhibition on Temozolomide Therapy in Glioblastoma
- (2017) Sani H. Kizilbash et al. MOLECULAR CANCER THERAPEUTICS
- 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity
- (2017) Parker L. Sulkowski et al. Science Translational Medicine
- PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA
- (2017) Tovah A. Day et al. Nature Communications
- Phase I, Dose-Escalation, Two-Part Trial of the PARP Inhibitor Talazoparib in Patients with Advanced Germline BRCA1/2 Mutations and Selected Sporadic Cancers
- (2017) Johann de Bono et al. Cancer Discovery
- Poly-(ADP-ribose)-polymerase inhibitors as radiosensitizers: a systematic review of pre-clinical and clinical human studies
- (2017) Paul Lesueur et al. Oncotarget
- Translational research in radiobiology in the framework of France HADRON national collaboration
- (2017) Claire Rodriguez-Lafrasse et al. Translational Cancer Research
- A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma
- (2016) Elias A. El-Habr et al. ACTA NEUROPATHOLOGICA
- The anti‐hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ‐dependent inhibition of the AKT pathway
- (2016) Suzana Assad Kahn et al. EMBO Molecular Medicine
- Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors
- (2016) Ann-Gerd Thorsell et al. JOURNAL OF MEDICINAL CHEMISTRY
- Dosimetry for radiobiology experiments at GANIL
- (2016) Florent Durantel et al. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT
- Cellular and molecular portrait of eleven human glioblastoma cell lines under photon and carbon ion irradiation
- (2015) S. Ferrandon et al. CANCER LETTERS
- Selective Inhibition of Parallel DNA Damage Response Pathways Optimizes Radiosensitization of Glioblastoma Stem-like Cells
- (2015) S. U. Ahmed et al. CANCER RESEARCH
- Discovery and Characterization of (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP-ribose) Polymerase-1/2 Inhibitor, as an Anticancer Agent
- (2015) Bing Wang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Carbon-ion beams effectively induce growth inhibition and apoptosis in human neural stem cells compared with glioblastoma A172 cells
- (2015) Mayu Isono et al. JOURNAL OF RADIATION RESEARCH
- Carbon ion radiotherapy in Japan: an assessment of 20 years of clinical experience
- (2015) Tadashi Kamada et al. LANCET ONCOLOGY
- Multi-factor data normalization enables the detection of copy number aberrations in amplicon sequencing data
- (2014) Valentina Boeva et al. BIOINFORMATICS
- Poly(ADP-ribose) polymerases in double-strand break repair: Focus on PARP1, PARP2 and PARP3
- (2014) Carole Beck et al. EXPERIMENTAL CELL RESEARCH
- BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51
- (2014) W. Qi et al. JOURNAL OF CELL SCIENCE
- The epidemiology of glioma in adults: a "state of the science" review
- (2014) Q. T. Ostrom et al. NEURO-ONCOLOGY
- PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways
- (2014) Carole Beck et al. NUCLEIC ACIDS RESEARCH
- A Monte Carlo study for the calculation of the average linear energy transfer (LET) distributions for a clinical proton beam line and a radiobiological carbon ion beam line
- (2014) F Romano et al. PHYSICS IN MEDICINE AND BIOLOGY
- Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma-initiating cells
- (2013) M Venere et al. CELL DEATH AND DIFFERENTIATION
- Evaluation of the pharmacodynamics and pharmacokinetics of the PARP inhibitor olaparib: a Phase I multicentre trial in patients scheduled for elective breast cancer surgery
- (2013) Nigel Bundred et al. INVESTIGATIONAL NEW DRUGS
- The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair
- (2013) Amanda L. Fenton et al. NUCLEIC ACIDS RESEARCH
- Comparison of carbon ion radiotherapy to photon radiation alone or in combination with temozolomide in patients with high-grade gliomas: Explorative hypothesis-generating retrospective analysis
- (2013) Stephanie E. Combs et al. RADIOTHERAPY AND ONCOLOGY
- Radiosensitization effect of poly(ADP-ribose) polymerase inhibition in cells exposed to low and high liner energy transfer radiation
- (2012) Takahisa Hirai et al. CANCER SCIENCE
- LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets
- (2012) Andreas Wilm et al. NUCLEIC ACIDS RESEARCH
- Repair of DNA damage induced by accelerated heavy ions-A mini review
- (2011) Ryuichi Okayasu INTERNATIONAL JOURNAL OF CANCER
- Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: One step forward, and one step back?
- (2011) Stephanie E Combs et al. Radiation Oncology
- CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of long-term cultured cancer stem cells from human malignant glio-neuronal tumors
- (2010) Cristina Patru et al. BMC CANCER
- PTEN Loss Compromises Homologous Recombination Repair in Astrocytes: Implications for Glioblastoma Therapy with Temozolomide or Poly(ADP-Ribose) Polymerase Inhibitors
- (2010) B. McEllin et al. CANCER RESEARCH
- Patterns of failure and comparison of different target volume delineations in patients with glioblastoma treated with conformal radiotherapy plus concomitant and adjuvant temozolomide
- (2010) Giuseppe Minniti et al. RADIOTHERAPY AND ONCOLOGY
- The Neuropharmacokinetics of Temozolomide in Patients with Resectable Brain Tumors: Potential Implications for the Current Approach to Chemoradiation
- (2009) J. Portnow et al. CLINICAL CANCER RESEARCH
- ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
- (2009) Yifang Hu et al. JOURNAL OF IMMUNOLOGICAL METHODS
- A New Model for Prediction of Drug Distribution in Tumor and Normal Tissues: Pharmacokinetics of Temozolomide in Glioma Patients
- (2008) L. Rosso et al. CANCER RESEARCH
- Phase I Study of the Poly(ADP-Ribose) Polymerase Inhibitor, AG014699, in Combination with Temozolomide in Patients with Advanced Solid Tumors
- (2008) R. Plummer et al. CLINICAL CANCER RESEARCH
- Replication-Dependent Radiosensitization of Human Glioma Cells by Inhibition of Poly(ADP-Ribose) Polymerase: Mechanisms and Therapeutic Potential
- (2008) Fiona A. Dungey et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started