Article
Geriatrics & Gerontology
Leon Lenchik, Ryan Barnard, Robert D. Boutin, Stephen B. Kritchevsky, Haiying Chen, Josh Tan, Peggy M. Cawthon, Ashley A. Weaver, Fang-Chi Hsu
Summary: This study developed a fully automated method for muscle measurement on CT images and found that higher paraspinous skeletal muscle area and skeletal muscle density were associated with better survival in older men, but not in women.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Article
Nutrition & Dietetics
Mesut Gumussoy, Volkan Atmis, Ahmet Yalcin, Remzi Bahsi, Seher Yigit, Sinan Ari, Haydar Can Dokuyan, Melih Gaffar Gozukara, Kamile Silay
Summary: This study evaluated the relationship between Malnutrition-sarcopenia syndrome (MSS) and all-cause mortality in hospitalised older Turkish people over two years. The results showed that MSS, sarcopenia, sarcopenia with malnutrition risk, and malnutrition groups were independently associated with higher mortality rates. MSS group had the highest hazard ratio and the worst survival curve among the study groups. Measures to prevent both sarcopenia and malnutrition are needed to reduce adverse health outcomes such as mortality in hospitalized older individuals.
CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Ayano Nagano, Masami Onaka, Keisuke Maeda, Junko Ueshima, Akio Shimizu, Yuria Ishida, Shinsuke Nagami, Shuzo Miyahara, Keiji Nishihara, Akiyuki Yasuda, Shosuke Satake, Naoharu Mori
Summary: This study aimed to investigate the prevalence, progression, and distinct attributes of sarcopenic dysphagia (SD) in geriatric medicine. The study found that SD was common among older patients and those with SD showed a better recovery rate compared to other types of dysphagia. Patients with SD had compromised nutritional profiles, diminished energy and protein consumption, and extended fasting durations. Thus, an integrated approach in geriatric medicine is crucial for addressing SD.
Article
Geriatrics & Gerontology
Gabriela Cabett Cipolli, Daniela de Assumpcao, Ivan Aprahamian, Deusivania Vieira da Silva Falcao, Meire Cachioni, Samila Sathler Tavares Batistoni, Ruth Caldeira de Melo, Ligiana Pires Corona, Anita Liberalesso Neri, Qian-Li Xue, Flavia Silva Arbex Borim, Monica Sanches Yassuda
Summary: This study aimed to investigate the longitudinal association between cognitive impairment and sarcopenia among Brazilian older adults. The results showed that cognitive impairment, age, weight, and baseline health status predicted the development of sarcopenia after 9 years.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2023)
Article
Education, Special
B. Valentin, D. Maes-Festen, J. Schoufour, A. Oppewal
Summary: This study explores the association between sarcopenia and 5-year mortality in older adults with intellectual disabilities (ID). The results show that sarcopenia is an independent risk factor for early mortality in this population, highlighting the importance of delaying the development of sarcopenia in older adults with ID.
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH
(2023)
Article
Geriatrics & Gerontology
Bing Lu, Lingyu Shen, Haiqiong Zhu, Ling Xi, Wei Wang, Xiaojun Ouyang
Summary: This study investigated the prevalence of sarcopenia among older Chinese adults and found that serum homocysteine levels were independently associated with sarcopenia. Additionally, female subjects and patients with hyperhomocysteinemia had a higher risk of developing sarcopenia.
Article
Geriatrics & Gerontology
M. Nagae, H. Umegaki, A. Yoshiko, K. Fujita, H. Komiya, K. Watanabe, Y. Yamada, T. Sakai
Summary: This study aimed to examine the association between muscle evaluation and hospital-associated disability (HAD), and found that thigh muscle thickness (BATT) was independently associated with mobility impairments, while other muscle indicators showed no significant association with self-care impairments. Therefore, it is necessary to reconsider muscle assessment methods in hospitalized older adults and consider comprehensive interventions to improve self-care.
JOURNAL OF NUTRITION HEALTH & AGING
(2022)
Article
Cardiac & Cardiovascular Systems
Sohyun Chun, Dong Wook Shin, Kyungdo Han, Jin Hyung Jung, Bongseong Kim, Hee-Won Jung, Ki Young Son, Seung-Pyo Lee, Sang Chol Lee
Summary: The study concluded that slower Timed Up and Go test speed is associated with a higher risk of myocardial infarction, congestive heart failure, and mortality in older adults.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2021)
Article
Multidisciplinary Sciences
Li Zhang, Jun Jin, You-Yi Tu, Zhe Zhao, Jun Tao, Xiao-yan Zhang
Summary: This study aimed to investigate the performance of the serum creatinine/cystatin C ratio (Cr/CysC) in predicting all-cause mortality in elders over 80 years. The study found that non-survivors with lower baseline Cr/CysC levels had a significantly higher mortality rate, and Cr/CysC levels were positively correlated with calf circumference and handgrip strength. Age, coronary heart disease, and the lowest Cr/CysC level were independent factors of all-cause mortality in older adults over 80 years.
Article
Geriatrics & Gerontology
Lingling Xie, Jiaojiao Jiang, Hongbo Fu, Wenyi Zhang, Ling Yang, Ming Yang
Summary: This study aimed to explore the associations of Global Leadership Initiative on Malnutrition (GLIM)-defined malnutrition with muscle mass, muscle quality, and muscle strength in hospitalized older adults.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Geriatrics & Gerontology
Amy Attaway, Annette Bellar, Faty Dieye, Douglas Wajda, Nicole Welch, Srinivasan Dasarathy
Summary: The study revealed that in hospitalized patients with heart failure, older age was associated with a higher prevalence of muscle loss phenotype, leading to worse clinical outcomes for the patients.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2021)
Article
Geriatrics & Gerontology
Edson J. Ascencio, Gustavo D. Cieza-Gomez, Rodrigo M. Carrillo-Larco, Pedro J. Ortiz
Summary: This study aimed to investigate the Timed Up and Go test and gait speed as predictors of mortality in older people in Peru. The results showed that in addition to established risk factors, the Timed Up and Go test was a significant predictor of all-cause mortality.
Article
Endocrinology & Metabolism
Namki Hong, Seung Won Burm, Hyeon Chang Kim, Chang Oh Kim, Yumie Rhee
Summary: Low countermovement jump power is associated with prevalent fracture, osteoporosis, and sarcopenia in older adults. However, whether jump power predicts incident fracture risk remains uninvestigated. This study found that low jump power is associated with a higher risk of fracture in older adults and can predict fracture risk independently of sarcopenia and osteoporosis.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Geriatrics & Gerontology
Suey S. Y. Yeung, Ruth S. M. Chan, Timothy Kwok, Jenny S. W. Lee, Jean Woo
Summary: The study showed that malnutrition classified according to GLIM criteria was significantly associated with sarcopenia, frailty, and mortality in community-dwelling Chinese older adults. However, there was no significant association found for falls, mobility limitation, and hospitalization.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Review
Geriatrics & Gerontology
Robin M. Daly, S. Iuliano, J. J. Fyfe, D. Scott, B. Kirk, M. Q. Thompson, E. Dent, K. Fetterplace, O. R. L. Wright, G. S. Lynch, J. Zanker, S. Yu, S. Kurrle, R. Visvanathan, A. B. Maier
Summary: This paper provides an up-to-date overview of screening, diagnosis, and management of sarcopenia and frailty in older hospitalized patients. The expert working group concluded that there is insufficient evidence to support any specific screening tool for sarcopenia, but recommended assessing probable sarcopenia in older hospitalized patients. For frailty, it is recommended to screen all hospitalized patients aged 70 years and older and further clinically assess those screened as positive. For the treatment of sarcopenia, sarcopenia, or frailty, a structured exercise program and nutritional support are recommended.
JOURNAL OF NUTRITION HEALTH & AGING
(2022)
Article
Geriatrics & Gerontology
Dan Liu, Long Zhou, Ming Yang, Roger S. McIntyre, Bing Cao
Summary: The objective of this study was to examine the associations between different types of dietary fat intakes and cognitive outcomes among elder adults. The results showed that dietary intake of PUFA and co-6 fatty acid were positively associated with cognitive performance, while GGT was negatively associated. Uric acid was positively associated with cognitive scores. The findings suggest that dietary PUFAs may reduce the risk of cognitive impairment by lowering oxidative stress.
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
(2022)
Article
Geriatrics & Gerontology
Lingling Xie, Jiaojiao Jiang, Hongbo Fu, Wenyi Zhang, Ling Yang, Ming Yang
Summary: This study aimed to explore the associations of Global Leadership Initiative on Malnutrition (GLIM)-defined malnutrition with muscle mass, muscle quality, and muscle strength in hospitalized older adults.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Geriatrics & Gerontology
Yanjiao Shen, Li Luo, Hongbo Fu, Lingling Xie, Wenyi Zhang, Jing Lu, Ming Yang
Summary: This study aimed to investigate the relationship between muscle mass and muscle quality indicators derived from opportunistic chest CT images and in-hospital death, length of hospital stay, and hospital costs in older patients. The study found that the CT-derived muscle mass indicator can serve as a prognostic factor for predicting in-hospital death, but it is not significantly related to hospital stay duration or increased hospital costs.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Letter
Geriatrics & Gerontology
Lingling Xie, Ming Yang
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Geriatrics & Gerontology
Tianjiao Tang, Lingling Xie, Song Hu, Lingling Tan, Xiaozhen Lei, Xiaozhen Luo, Ling Yang, Ming Yang
Summary: CCR and SI have satisfactory and comparable diagnostic accuracy and prognostic values for sarcopenia in patients with advanced NSCLC, and can serve as surrogate biomarkers for evaluating sarcopenia in these patients.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Otorhinolaryngology
Xiaofan Jing, Ming Yang, Yuan Liu, Yan Wang, Jingjing Li, Wen Hu
Summary: This study investigated the possible associations of chest CT-determined trunk muscle mass and quality with dysphagia in older inpatients. The results demonstrated that muscle mass was negatively associated with dysphagia, while intermuscular adipose tissue and its percentage were positively associated with dysphagia. However, muscle density was not significantly associated with dysphagia.
Review
Dermatology
Xiaomei Chen, Hongmei Xiang, Ming Yang
Summary: This study summarized the evidence regarding the effectiveness and safety of using topical cetirizine for treating androgenetic alopecia, suggesting that 1% topical cetirizine may be more effective than a placebo. However, compared to minoxidil, it was found to be less effective in improving total and vellus hair density, but it may have a longer-lasting effect.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Medicine, General & Internal
Xiaofan Jing, Yuxiang Liang, Renjie Wang, Hongbo Fu, Jiaojiao Jiang, Ming Yang
Summary: Obesity is a global public health challenge, and dietary supplements that can improve muscle mass and function are needed. This study aims to evaluate the effectiveness and safety of HMB-enriched nutritional supplements in obese adults during calorie restriction, focusing on muscle mass and muscle function.
Article
Geriatrics & Gerontology
Xiaoyan Chen, Gongxiang Liu, Siyuan Li, Xiufang Lin, Zhenli Han, Xiaoyi Hu, Jinhui Wu, Ming Yang
Summary: The different measurement protocols for handgrip strength recommended by the AWGS 2019 update significantly affect the measurement values and identification of handgrip strength asymmetry, but not handgrip strength weakness.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2023)
Review
Geriatrics & Gerontology
Hongbo Fu, Lei Wang, Wenyi Zhang, Jing Lu, Ming Yang
Summary: This review summarizes the current knowledge on the diagnostic accuracy of muscle ultrasound for the diagnosis of sarcopenia. The study found that muscle ultrasound shows a low-to-moderate diagnostic test accuracy for sarcopenia diagnosis depending on different ultrasound parameters, measured muscles, reference standards, and study populations.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Nutrition & Dietetics
Jinqiu Zhou, Li Luo, Lingling Xie, Song Hu, Lingling Tan, Xiaozhen Lei, Xiaozhen Luo, Ming Yang
Summary: The ESPEN and EASO have released the international consensus on the diagnostic criteria for sarcopenic obesity (SO), recommending skeletal muscle mass adjusted for body weight (SMM/W) for determining low muscle mass. This study aimed to evaluate the agreement between different diagnostic criteria for SO and to compare their predictive abilities for mortality in patients with advanced NSCLC. The results showed that SOESPEN, SOESPEN-M, and SOAWGS were significantly associated with mortality, while SOCT and SOFM were not.
CLINICAL NUTRITION
(2023)
Review
Geriatrics & Gerontology
Rongna Lian, Gengchen Jiang, Qianqian Liu, Qiling Shi, Shuyue Luo, Jing Lu, Ming Yang
Summary: Choosing the optimal sarcopenia screening tool for specific clinical scenarios is challenging. This scoping review summarized all validated sarcopenia screening tools and their diagnostic accuracy in different populations. Over 50 validated tools were identified for screening sarcopenia in various clinical settings.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2023)
Article
Geriatrics & Gerontology
Xiaoyan Chen, Lingling Xie, Xin Xia, Xiaozhen Luo, Jing Chen, Jing Zhang, Qinlan Li, Xuemei Zhang, Jiaojiao Jiang, Ming Yang
Summary: Both measurement protocols and repetitions significantly affect the maximal handgrip strength values, but have minimal impact on the identification of handgrip weakness.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Nutrition & Dietetics
Wenyi Zhang, Jing Tang, Huiyu Tang, Lingling Xie, Jing Wang, Jinhui Wu, Ming Yang
Summary: This study compared the predictive effects of SMD-defined and IMAT-defined myosteatosis on OS in patients with advanced NSCLC, and found that patients with both low SMD and high IMAT had a shorter OS.
CLINICAL NUTRITION
(2023)
Review
Medicine, General & Internal
Xiaomei Chen, Jiaojiao Jiang, Renjie Wang, Hongbo Fu, Jing Lu, Ming Yang
Summary: The review indicated that the effectiveness of chest physiotherapy for improving mortality and cure rate in pneumonia patients is uncertain, but certain physiotherapies may help shorten hospital stays, fever duration, and ICU stays.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2022)
