ITGB1-dependent upregulation of Caveolin-1 switches TGFβ signalling from tumour-suppressive to oncogenic in prostate cancer

The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer cells

(2017) L Mi et al.   ONCOGENE

Systems pathology by multiplexed immunohistochemistry and whole-slide digital image analysis

(2017) Sami Blom et al.   Scientific Reports

Loss of PTEN expression in ERG-negative prostate cancer predicts secondary therapies and leads to shorter disease-specific survival time after radical prostatectomy

(2016) Kanerva Lahdensuo et al.   MODERN PATHOLOGY

Caveolin-1 promotes Ewing sarcoma metastasis regulating MMP-9 expression through MAPK/ERK pathway

(2016) Laura Lagares-Tena et al.   Oncotarget

Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis

(2015) R. Strippoli et al.   EMBO Molecular Medicine

Caveolin-1-negative head and neck squamous cell carcinoma primary tumors display increased epithelial to mesenchymal transition and prometastatic properties

(2015) Alain C. Jung et al.   Oncotarget

The role of epithelial plasticity in prostate cancer dissemination and treatment resistance

(2014) Rhonda L. Bitting et al.   CANCER AND METASTASIS REVIEWS

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CAV-1 contributes to bladder cancer progression by inducing epithelial-to-mesenchymal transition

(2014) Wu Liang et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

PPARδ promotes oncogenic redirection of TGF-β1 signaling through the activation of the ABCA1-Cav1 pathway

(2013) Nam-Hu Her et al.   CELL CYCLE

Caveolin-1 as a promoter of tumour spreading: when, how, where and why

(2013) Rebecca Senetta et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer

(2013) H Moon et al.   ONCOGENE

Combination of Rapamycin, CI-1040, and 17-AAG Inhibits Metastatic Capacity of Prostate Cancer via Slug Inhibition

(2013) Guanxiong Ding et al.   PLoS One

Caveolin-1 silencing arrests the proliferation of metastatic lung cancer cells through the inhibition of STAT3 signaling

(2012) Fabia Pancotti et al.   CELLULAR SIGNALLING

Caveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesis

(2012) Upal K. Basu Roy et al.   INTERNATIONAL JOURNAL OF CANCER

A functional genetic screen reveals new regulators of  1-integrin activity

(2012) T. Pellinen et al.   JOURNAL OF CELL SCIENCE

Caveolar domain organization and trafficking is regulated by Abl kinases and mDia1

(2012) Asier Echarri et al.   JOURNAL OF CELL SCIENCE

Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

(2011) Jacky G. Goetz et al.   CELL

Caveolin-1 promotes pancreatic cancer cell differentiation and restores membranous E-cadherin via suppression of the epithelial-mesenchymal transition

(2011) Ahmed F. Salem et al.   CELL CYCLE

Switching TGFβ from a tumor suppressor to a tumor promoter

(2011) Gareth J Inman   CURRENT OPINION IN GENETICS & DEVELOPMENT

Critical and Reciprocal Regulation of KLF4 and SLUG in Transforming Growth Factor  -Initiated Prostate Cancer Epithelial-Mesenchymal Transition

(2011) Y.-N. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

SLUG promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis

(2011) Berna Uygur et al.   Molecular Cancer

SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

(2011) Zhihu Ding et al.   NATURE

The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk

(2011) E Arpaia et al.   ONCOGENE

siRNA Knockdown of Ribosomal Protein Gene RPL19 Abrogates the Aggressive Phenotype of Human Prostate Cancer

(2011) Alix Bee et al.   PLoS One

TGF-β1-induced EMT of non-transformed prostate hyperplasia cells is characterized by early induction of SNAI2/Slug

(2011) Eva Slabáková et al.   PROSTATE

Molecular Target Class Is Predictive of In vitro Response Profile

(2010) Joel Greshock et al.   CANCER RESEARCH

PAI-1 Mediates the TGF-β1+EGF-Induced “Scatter” Response in Transformed Human Keratinocytes

(2010) Jennifer Freytag et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Slug/SNAI2 regulates cell proliferation and invasiveness of metastatic prostate cancer cell lines

(2010) Modjtaba Emadi Baygi et al.   TUMOR BIOLOGY

A single-array preprocessing method for estimating full-resolution raw copy numbers from all Affymetrix genotyping arrays including GenomeWideSNP 5 & 6

(2009) Henrik Bengtsson et al.   BIOINFORMATICS

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Caveolin-1 Promotes Autoregulatory, Akt-Mediated Induction of Cancer-Promoting Growth Factors in Prostate Cancer Cells

(2009) L. Li et al.   MOLECULAR CANCER RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Caveolin-1 in tumor progression: the good, the bad and the ugly

(2008) Jacky G. Goetz et al.   CANCER AND METASTASIS REVIEWS

Epithelial to mesenchymal transition (EMT) in human prostate cancer: lessons learned from ARCaP model

(2008) Haiyen E. Zhau et al.   CLINICAL & EXPERIMENTAL METASTASIS

Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues

(2008) Sami Kilpinen et al.   GENOME BIOLOGY