Liquid-Liquid Phase Separation of Patchy Particles Illuminates Diverse Effects of Regulatory Components on Protein Droplet Formation

Intrinsically Disordered Protein Exhibits Both Compaction and Expansion under Macromolecular Crowding

(2018) Anthony Banks et al.   BIOPHYSICAL JOURNAL

Electrostatic Interactions in Protein Structure, Folding, Binding, and Condensation

(2018) Huan-Xiang Zhou et al.   CHEMICAL REVIEWS

Why Do Disordered and Structured Proteins Behave Differently in Phase Separation?

(2018) Huan-Xiang Zhou et al.   TRENDS IN BIOCHEMICAL SCIENCES

Intrinsically Disordered Regions Can Contribute Promiscuous Interactions to RNP Granule Assembly

(2018) David S.W. Protter et al.   Cell Reports

Sequence determinants of protein phase behavior from a coarse-grained model

(2018) Gregory L. Dignon et al.   PLoS Computational Biology

Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles

(2017) Ming-Tzo Wei et al.   Nature Chemistry

Charge pattern matching as a ‘fuzzy’ mode of molecular recognition for the functional phase separations of intrinsically disordered proteins

(2017) Yi-Hsuan Lin et al.   NEW JOURNAL OF PHYSICS

Transfer matrix theory of polymer complex coacervation

(2017) Tyler K. Lytle et al.   Soft Matter

Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism

(2016) Shambaditya Saha et al.   CELL

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

(2016) Marina Feric et al.   CELL

Sequence-Specific Polyampholyte Phase Separation in Membraneless Organelles

(2016) Yi-Hsuan Lin et al.   PHYSICAL REVIEW LETTERS

Modeling phase transitions in mixtures of β–γ lens crystallins

(2016) Miha Kastelic et al.   Soft Matter

Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3

(2016) Jarrett Smith et al.   eLife

Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA

(2016) Diana M Mitrea et al.   eLife

Biomolecular interactions modulate macromolecular structure and dynamics in atomistic model of a bacterial cytoplasm

(2016) Isseki Yu et al.   eLife

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

RNA Controls PolyQ Protein Phase Transitions

(2015) Huaiying Zhang et al.   MOLECULAR CELL

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II

(2015) Kathleen A. Burke et al.   MOLECULAR CELL

Polymer physics of intracellular phase transitions

(2015) Clifford P. Brangwynne et al.   Nature Physics

How fluorescent labelling alters the solution behaviour of proteins

(2015) M. K. Quinn et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

Crowding-Induced Phase Separation of Lennard-Jones Particles: Implications to Nuclear Structures in a Biological Cell

(2012) Eun Jin Cho et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

Phase separation in solutions of monoclonal antibodies and the effect of human serum albumin

(2011) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phase behavior of mixtures of human lens proteins Gamma D and Beta B1

(2010) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE

Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences

(2008) Huan-Xiang Zhou et al.   Annual Review of Biophysics