Article
Engineering, Environmental
Evren Yildiztugay, Ceyda Ozfidan-konakci, Busra Arikan, Fatma Nur Alp-Turgut, Cagri Guenturk
Summary: The toxicity mechanisms of individual exposure of arsenic (As) and fluoride (F) and their interactions with biochar (BC) are not well understood. This study investigated the defense responses of Lemna minor to combined exposure of As and F under different BC concentrations and found that BC can mitigate the negative effects of As and F on plants.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Yingyun Gong, Yanfeng Xue, Xin Li, Zhao Zhang, Wenjun Zhou, Paola Marcolongo, Angiolo Benedetti, Shengyong Mao, Leng Han, Guolian Ding, Zheng Sun
Summary: The rise of metabolic disorders in modern times is mainly attributed to the environment, while heritable effects of environmental chemicals on mammalian offspring's metabolic health are unclear. Research has found sex- and generation-specific heritable effects of inorganic arsenic on metabolic physiology, highlighting the importance of gene-environment interactions.
Review
Medicine, General & Internal
Sajin Bae, Elena Kamynina, Heather M. Guetterman, Adetutu F. Farinola, Marie A. Caudill, Robert J. Berry, Patricia A. Cassano, Patrick J. Stover
Summary: The provision of folic acid supplements may benefit blood arsenic concentration, urinary arsenic methylation profiles, and plasma homocysteine concentration versus placebo with moderate-certainty evidence. Furthermore, there is low-certainty evidence that folic acid supplements plus other nutrients may benefit blood arsenic and plasma homocysteine concentrations versus nutrients alone. Given the limited number of studies, more research is needed to assess the effects of folic acid on arsenic-related health outcomes in diverse settings.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Environmental Sciences
Usama Alshana, Beril Altun, Nusret Ertas, Gonca cakmak, Ela Kadioglu, Deniz Hisarli, Elif Asik, Esref Atabey, Celalettin Rumi celebi, Nazmi Bilir, Hakan Serge, A. Murat Tuncer, Sema Burgaz
Summary: This study investigated the exposure, metabolism, and health effects of arsenic contamination in drinking water in the Central Anatolian region of Turkey. It was found that residents in the exposed group were chronically exposed to low-to-moderate levels of arsenic, but there was no significant increase in the frequency of skin lesions. Long-term follow-up studies are necessary to further understand the health effects in this region.
Article
Environmental Sciences
Xushen Chen, Ying Cheng, Xiaolin Tian, Jia Li, Xiaodong Ying, Qiuyi Zhao, Meng Wang, Yan Liu, Yulan Qiu, Xiaoyan Yan, Xuefeng Ren
Summary: The study aimed to determine the impact of inorganic arsenic (iAs) exposure on urinary microbiome and metabolome, and to identify microbiota and metabolic signatures associated with iAs-induced bladder lesions. The results showed that iAs exposure not only caused bladder lesions, but also disrupted the composition of urinary microbiome and related metabolic profiles. The differential microbiota and metabolites identified could potentially serve as urinary biomarkers for iAs-induced bladder cancer.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Agronomy
Magin Gonzalez-Moscoso, Nadia Martinez-Villegas, Gregorio Cadenas-Pliego, Antonio Juarez-Maldonado
Summary: Both forms of arsenic negatively affect tomato growth and yield, but SiO2 NPs can reduce arsenic uptake. SiO2 NPs also enhance the accumulation of Fe and Zn, and increase chlorophyll and antioxidant enzyme content.
Article
Biochemistry & Molecular Biology
Gaoyang Qu, Zi Liu, Jiaxin Zhang, Yaning Guo, Hui Li, Ruijie Qu, Wei Su, Huan Zhang, Lin Zhang, Hong Xu, Fuhai Shen, Shoufang Jiang, Heliang Liu, Jinlong Li
Summary: In this study, the effects of inorganic arsenic on hepatic macrophage polarization were investigated, as well as the role of PINK1/Parkin-mediated mitophagy in regulating this metalloid-induced polarization. Results revealed that acute arsenic exposure led to macrophage polarization and disruptions in hepatic redox balance and mitophagy activation. Furthermore, it was suggested that PINK1/Parkin-mediated mitophagy may contribute to the resistance of hepatic macrophages to arsenic-induced up-regulation of gene expression.
Review
Toxicology
Miroslav Styblo, Abhishek Venkatratnam, Rebecca C. Fry, David J. Thomas
Summary: Methylation of inorganic arsenic is both a detoxification pathway and a mechanism for initiating disease.
ARCHIVES OF TOXICOLOGY
(2021)
Article
Multidisciplinary Sciences
Mohammad Al-Forkan, Fahmida Binta Wali, Laila Khaleda, Md Jibran Alam, Rahee Hasan Chowdhury, Amit Datta, Md Zillur Rahman, Nazmul Hosain, Mohammad Fazle Maruf, Muhammad Abdul Quaium Chowdhury, N. K. M. Mirazul Hasan, Injamamul Ismail Shawon, Rubhana Raqib
Summary: The study found that CVD patients from arsenic-affected areas had significantly higher concentrations of iAs in their urine, nail, and cardiac tissue samples, and these were associated with specific genotypes. Adjusted analyses also showed associations between iAs concentrations and certain gene polymorphisms, indicating a potential susceptibility role of these SNPs in cardiac tissue injury among CVD patients exposed to iAs.
SCIENTIFIC REPORTS
(2021)
Article
Environmental Sciences
Selim Reza Tony, Nazmul Haque, Abu Eabrahim Siddique, Moriom Khatun, Mizanur Rahman, Zohurul Islam, Md Shofikul Islam, Jahidul Islam, Shakhawoat Hossain, Md Ashraful Hoque, Zahangir Alam Saud, Daigo Sumi, Abdus S. Wahed, Aaron Barchowsky, Seiichiro Himeno, Khaled Hossain
Summary: Chronic exposure to arsenic in drinking water increases serum levels of periostin, and elevated periostin levels are associated with Th2-mediated asthma.
Article
Biochemistry & Molecular Biology
Jin Cheng, Yuanyuan Li, Qian He, Lanrong Luo, Yanting Zhang, Yanhui Gao, Hongqi Feng, Lijun Zhao, Wei Wei, Songbo Fu, Dianjun Sun
Summary: The study found that ADIPQO/rs266729 and FABP2/rs1799883 gene polymorphisms affect susceptibility to essential hypertension in individuals exposed to high levels of arsenic; there was a clear difference in the urinary arsenic metabolism pattern between hypertensive patients and controls.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2021)
Article
Chemistry, Analytical
Zhan-Biao Ge, Ming-Ming Chen, Wan-Ying Xie, Ke Huang, Fang-Jie Zhao, Peng Wang
Summary: In this study, a novel approach utilizing a bacterial biosensor in conjunction with amylase hydrolysis was developed for high-throughput detection of inorganic arsenic (iAs) in rice grains. The biosensor demonstrated high specificity and was able to distinguish between arsenite [As(III)] and arsenate [As(V)]. The results obtained using this method were comparable to the standard technique of microwave digestion coupled with HPLC-ICP-MS. The biosensor exhibited excellent reproducibility and a high signal-to-noise ratio, with lower limits of detection than the maximum allowable level for infant rice supplements established by the European Union.
ANALYTICAL CHEMISTRY
(2023)
Article
Biodiversity Conservation
Claudia Tanamal, Jules M. Blais, Emmanuel Yumvihoze, Hing Man Chan
Summary: A study conducted in Yellowknife, Canada, examined the arsenic concentrations in fish and the consumption habits of residents. The main arsenic species found in fish was nontoxic arsenobetaine, indicating low health risks associated with arsenic exposure.
HUMAN AND ECOLOGICAL RISK ASSESSMENT
(2021)
Article
Environmental Sciences
Raquel Soler-Blasco, Florencia Harari, Gabriel Riutort-Mayol, Mario Murcia, Manuel Lozano, Amaia Irizar, Loreto Santa Marina, Miren Begona Zubero, Nora Fernandez-Jimenez, Simone Braeuer, Ferran Ballester, Sabrina Llop
Summary: This study investigated the role of genetic polymorphisms in AS3MT, GSTO2, N6AMT1, MTHFR, MTR, FTCD, CBS, and FOLH1 in inorganic arsenic (iAs) methylation efficiency during pregnancy. The results showed that ancestral alleles in AS3MT polymorphisms were associated with lower iAs methylation efficiency, and FOLH1 also played a role in iAs methylation efficiency.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Ecology
Julieta Sturla Lompre, Erica Giarratano, Monica Noemi Gil, Lidwina Bertrand, Gabriela Malanga
Summary: Laboratory studies were conducted to investigate the effects of acute arsenic exposure on the Aequipecten tehuelchus scallops. The accumulation of arsenic in various tissues was analyzed, and it was found that the accumulation increased linearly with exposure concentration. The scallops showed relatively high tolerance to arsenic, as evidenced by a median lethal concentration (LC50) value of 7.1 mg As/L. The potential effects of arsenic on oxidative stress and antioxidant defense mechanisms were also studied, and it was observed that the scallops were able to counteract the effects of arsenic through induction of biotransformation pathways and antioxidant defense mechanisms.
REGIONAL STUDIES IN MARINE SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Mang Li, Yanhui Gao, Jing Cui, Yuanyuan Li, Bingyun Li, Yang Liu, Jing Sun, Xiaona Liu, Hongxu Liu, Lijun Zhao, Dianjun Sun
BIOLOGICAL TRACE ELEMENT RESEARCH
(2016)
Article
Cell Biology
Xiaona Liu, Yanhui Gao, Yuan An, Xiaoyan Fu, Yuanyuan Li, Dianjun Sun, Jing Wang
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
(2015)
Article
Peripheral Vascular Disease
Jie Lou, Dan Zhao, Ling-Ling Zhang, Shu-Ying Song, Yan-Chao Li, Fei Sun, Xiao-Qing Ding, Chang-Jiang Yu, Yuan-Yuan Li, Mei-Tong Liu, Chang-Jiang Dong, Yong Ji, Hongliang Li, Wenfeng Chu, Zhi-Ren Zhang
Article
Biotechnology & Applied Microbiology
Yu Liu, Dan Zhao, Fang Qiu, Ling-Ling Zhang, Shang-Kun Liu, Yuan-Yuan Li, Mei-Tong Liu, Di Wu, Jia-Xin Wang, Xiao-Qing Ding, Yan-Xin Liu, Chang-Jiang Dong, Xiao-Qi Shao, Bao-Feng Yang, Wen-Feng Chu
Article
Oncology
Yu Liu, Duo Li, Dan Nie, Shang-Kun Liu, Fang Qiu, Mei-Tong Liu, Yuan-Yuan Li, Jia-Xin Wang, Yan-Xin Liu, Chang-Jiang Dong, Di Wu, Wei Tian, Jia Yang, Wei Mu, Jia-Tong Li, Dan Zhao, Xiao-Feng Wang, Wen-Feng Chu, Bao-Feng Yang
Article
Biotechnology & Applied Microbiology
Liru Yan, Xuna Zhang, Yujie Guo, Yuanyuan Li, Zonghong Liu
BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT
(2018)
Article
Biochemistry & Molecular Biology
Yanting Zhang, Yuanyuan Li, Lanrong Luo, Qian He, Yanhui Gao, Hongqi Feng, Lijun Zhao, Wei Wei, Songbo Fu, Dianjun Sun
BIOLOGICAL TRACE ELEMENT RESEARCH
(2019)
Article
Biochemistry & Molecular Biology
Xiangnan Guo, Xiaoyan Fu, Xiaona Liu, Jingqiu Wang, Zhongzhe Li, Lin Gao, Yuanyuan Li, Wei Zhang
BIOLOGICAL TRACE ELEMENT RESEARCH
(2019)
Article
Environmental Sciences
Wei Zhang, Xiaohui Cui, Yanhui Gao, Liyan Sun, Jing Wang, Yanmei Yang, Xiaona Liu, Yuanyuan Li, Xiangnan Guo, Dianjun Sun
Article
Environmental Sciences
Wei Zhang, Yanhui Gao, Guangqian Yu, Zhenbo Yang, Lijun Zhao, Xiaohong Ji, Yunpeng Ding, Wei Wang, Wei Wei, Yuanyuan Li, Lin Gao, Dianjun Sun
Summary: This report provides an overview of water-borne arsenicosis in China from 2001 to 2016, showing that a significant number of villages in China are at risk of high arsenic exposure, with an overall prevalence rate of arsenicosis at 1.93%. The study found that villages with arsenic-safe water supplies have lower prevalence rates of arsenicosis.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Jin Cheng, Yuanyuan Li, Qian He, Lanrong Luo, Yanting Zhang, Yanhui Gao, Hongqi Feng, Lijun Zhao, Wei Wei, Songbo Fu, Dianjun Sun
Summary: The study found that ADIPQO/rs266729 and FABP2/rs1799883 gene polymorphisms affect susceptibility to essential hypertension in individuals exposed to high levels of arsenic; there was a clear difference in the urinary arsenic metabolism pattern between hypertensive patients and controls.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2021)
Article
Environmental Sciences
Yuanyuan Li, Kun Liang, Lin Yuan, Jing Gao, Linquan Wei, Lijun Zhao
Summary: Antioxidant systems like Trx and Grx maintain oxidative stress balance. This study investigated the mechanisms of arsenic-induced liver injury and found that BSO exacerbated the toxicity of arsenic and affected the expression of the Trx and Grx systems. Trx had a longer-lasting impact and served as a backup antioxidant defense system in the liver.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Yuanyuan Li, Yuanyuan Zhang, Yanhui Gao, Wei Zhang, Xiaohui Cui, Junqiu Liu, Yudan Wei
BIOLOGICAL TRACE ELEMENT RESEARCH
(2018)
Article
Public, Environmental & Occupational Health
Wu Jun-hua, Qin Ming, Li Dan-dan, Yang Dan, Li Bing-yun, Liu Xiao-na, Li Mang, Li Yuan-yuan, Zhang Wei, Gao Yan-hui