Article
Oncology
Zheng-Yun Zhang, Jiao Guan, Xin-Ping Wang, Di-Si Hao, Zun-Qiang Zhou
Summary: Adolescent and young adult HCC patients have worse prognosis with more unfavorable pathological characteristics and higher recurrence rate and disease-related death rate.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2022)
Article
Oncology
Sarah Jane Commander, Marcelo Cerullo, Neha Arjunji, Harold J. Leraas, Steven Thornton, Kadiyala Ravindra, Elisabeth T. Tracy
Summary: This article examines the similarities and differences between pediatric and adult hepatocellular adenocarcinoma (HCC) patients. It finds that pediatric HCC patients have a more aggressive surgical approach, resulting in higher overall survival rates compared to adults. Age does not significantly contribute to survivorship.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Review
Oncology
Drishti Tolani, Julia Wilcox, Sharvari Shyam, Neha Bansal
Summary: As chemotherapy improves, understanding the effects on the cardiovascular system is increasingly important. Cardiotoxicity is a major determinant of morbidity and mortality in cancer survivors. New imaging modalities and biomarkers may detect subclinical cardiotoxicity earlier. Dexrazoxane remains the most effective therapy for preventing anthracycline-induced cardiomyopathy. Neurohormonal modulating drugs have not been effective in preventing cardiotoxicity. Advanced cardiac therapies, like heart transplant, should be considered for cancer survivors with end-stage HF. Research on genetic associations may produce treatments to reduce cardiovascular morbidity and mortality.
CURRENT TREATMENT OPTIONS IN ONCOLOGY
(2023)
Article
Oncology
Alessandro Anselmo, Leandro Siragusa, Paolo Brigato, Camilla Riccetti, Andrea Collini, Bruno Sensi, Giuseppe Tisone
Summary: This study compared the outcomes of primary liver transplantation (PLT) and salvage liver transplantation (SLT) for hepatocellular carcinoma (HCC) and found that PLT resulted in significantly longer disease-free survival, overall survival, and cancer-specific survival (CSS) compared to SLT. However, within the SLT group, there was no significant difference in disease-free survival between SLT-LR and SLT-RFA. These findings suggest that PLT may provide superior long-term oncological outcomes for HCC patients.
Article
Oncology
Elizabeth J. Siembida, Bryce B. Reeve, Brad J. Zebrack, Mallory A. Snyder, John M. Salsman
Summary: The study examined the variability in HRQOL among adolescent and young adult cancer survivors, finding that treatment status and developmental stage significantly impacted symptoms and functioning, with developmental stage being a more critical predictor than cancer type.
Article
Oncology
Julian Surujballi, Grace Chan, Caron Strahlendorf, Amirrtha Srikanthan
Summary: Adolescent and young adult (AYA) oncology patients have specialized needs and are underserved in Canada. This study identified the priority list and sequence for new AYA programs through literature review, consensus documents, and expert opinion. Stakeholders were engaged to co-develop program goals and activities, and the Delphi technique was used to prioritize implementation. The study found that patient care was the top priority, followed by HCP education, patient and family education, and program sustainability.
Article
Oncology
Tatsuo Akechi, Izumi Mishiro, Shinji Fujimoto
Summary: Adolescent and young adult (AYA) patients with cancer in Japan have a high risk of major depressive disorder (MDD), especially those with multiple cancer categories, leukemia, and those who receive aggressive anticancer treatments.
Article
Public, Environmental & Occupational Health
Eric Adjei Boakye, Katherine M. Polednik, Teresa L. Deshields, Arun Sharma, Yamile Molina, Lidia Schapira, Justin M. Barnes, Nosayaba Osazuwa-Peters
Summary: This study examined emotional distress in cancer survivors diagnosed as adolescents or young adults compared to survivors diagnosed as middle/older adults and the general population without a history of cancer. The findings showed that emotional distress was more prevalent among young adult cancer survivors than middle/older adult survivors. However, there was no difference in emotional distress between young adult cancer survivors and the general population without cancer.
ANNALS OF EPIDEMIOLOGY
(2022)
Review
Oncology
Leslie Coker Appiah, Yueyang Frances Fei, Mallery Olsen, Steven R. Lindheim, Diane M. Puccetti
Summary: This article addresses the impact of cancer and its treatments on fertility and reproductive health, highlighting disparities in access to fertility preservation care for the pediatric, adolescent, and young adult population. Further research is needed to improve care and address gaps in knowledge.
Article
Surgery
Maria Conticchio, Antonella Delvecchio, Valentina Ferraro, Matteo Stasi, Annachiara Casella, Nicola Chetta, Emma De Marinis, Andrea Madaro, Margherita Raele, Rosalinda Filippo, Michele Ammendola, Michele Tedeschi, Nicola deAngelis, Riccardo Memeo
Summary: Spontaneous rupture of hepatocellular carcinoma (HCC) is a rare complication, and its management requires considering the clinical conditions of the patient and the best curative treatment. We reported a case of an emergency robotic liver resection for a ruptured HCC in an elderly patient. Minimally invasive liver resection is currently recognized as a safe and feasible approach for the treatment of HCC in elderly patients.
INTERNATIONAL JOURNAL OF MEDICAL ROBOTICS AND COMPUTER ASSISTED SURGERY
(2023)
Article
Oncology
Zhancheng Qiu, Weili Qi, Youwei Wu, Lingling Li, Chuan Li
Summary: This study examines the impact of public insurance status on the survival outcomes of HCC patients after liver resection in China. The results show that underinsured HCC patients have worse survival outcomes after liver resection. This may be due to the limited access to care for underinsured patients, but further exploration is needed for conclusive evidence.
Review
Oncology
Mary Jane Lim-Fat, Maria Macdonald, Sarah Lapointe, Seth Andrew Climans, Chantel Cacciotti, Manik Chahal, Sebastien Perreault, Derek S. Tsang, Andrew Gao, Stephen Yip, Julia Keith, Julie Bennett, Vijay Ramaswamy, Jay Detsky, Uri Tabori, Sunit Das, Cynthia Hawkins
Summary: The 2021 World Health Organization classification of CNS tumors includes molecular signatures with histology and emphasizes the differences between pediatric and adult-type CNS tumors. This study aims to propose a comprehensive approach to molecular testing for adolescent and young adult (AYA) patients across this spectrum, in order to improve their diagnosis and care.
FRONTIERS IN ONCOLOGY
(2022)
Review
Oncology
Amirrtha Srikanthan, Jolanta Karpinski, Abha Gupta
Summary: The Canadian National AYA Cancer Task Force and Canadian Partnership Against Cancer have developed standardized criteria for structured academic programs in AYA Oncology in Canada, in order to meet the distinctive needs of this age group and advance AYA oncology care.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ningbin Luo, Xiangyang Huang, Yinan Ji, Guanqiao Jin, Yunying Qin, Bangde Xiang, Danke Su, Weizhong Tang
Summary: This study found that the functional liver imaging score (FLIS) based on preoperative gadoxetic acid-enhanced MRI can predict posthepatectomy liver failure (PHLF) in hepatocellular carcinoma (HCC) patients. FLIS has a higher predictive power than the MELD score, ALBI score, and ICG-R15 clearance.
EUROPEAN RADIOLOGY
(2022)
Article
Oncology
Morgan Young-Speirs, Caitlin Forbes, Michaela Patton, K. Brooke Russell, Mehak Stokoe, Kathleen Reynolds, Fiona Schulte
Summary: Survivors of childhood cancer have comparable perceived health to controls without cancer diagnosis, with pain, physical activity, and concerns related to health resources being significant predictors of perceived health. Understanding factors influencing perceived health in SCCs may help in developing interventions and further research.
