Hepatoprotective activity of iridoids, seco-iridoids and analog glycosides from Gentianaceae on HepG2 cells via CYP3A4 induction and mitochondrial pathway

Optimization of Aqueous Extraction and Biological Activity of Harpagophytum procumbens Root on Ex Vivo Rat Colon Inflammatory Model

(2017) Marcello Locatelli et al.   PHYTOTHERAPY RESEARCH

Protective Effects Induced by Microwave-Assisted Aqueous Harpagophytum Extract on Rat Cortex Synaptosomes Challenged with Amyloid β-Peptide

(2017) Claudio Ferrante et al.   PHYTOTHERAPY RESEARCH

Antiproliferative, Protective and Antioxidant Effects of Artichoke, Dandelion, Turmeric and Rosemary Extracts and Their Formulation

(2017) L. Menghini et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells

(2016) Ryosuke Negoro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gentiopicroside and sweroside from Veratrilla baillonii Franch. induce phosphorylation of Akt and suppress Pck1 expression in hepatoma cells

(2016) Xian-Ju Huang et al.   Biochemistry and Cell Biology

Chromatographic Evaluation and Characterization of Components of Gentian Root Extract Used as Food Additives

(2016) Yoshiaki Amakura et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Pretreatment with Rho-kinase inhibitor ameliorates lethal endotoxemia-induced liver injury by improving mitochondrial function

(2016) Renyu Ding et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Antitoxic effect of Veratrilla baillonii on the acute toxicity in mice induced by Aconitum brachypodum , one of the genus Aconitum

(2016) Yue-Bin Ge et al.   JOURNAL OF ETHNOPHARMACOLOGY

Mutations in TFAM, encoding mitochondrial transcription factor A, cause neonatal liver failure associated with mtDNA depletion

(2016) Ashlee R. Stiles et al.   MOLECULAR GENETICS AND METABOLISM

The water extract of Veratrilla baillonii could attenuate the subacute toxicity induced by Aconitum brachypodum

(2016) You Yu et al.   PHYTOMEDICINE

Antitoxic effect of baicalin and glycyrrhetic acid on PC12 cells induced by Aconitum brachypodum Diel

(2015) Huang Xian Ju et al.   African Journal of Pharmacy and Pharmacology

Comparative HPLC/ESI-MS and HPLC/DAD study of different populations of cultivated, wild and commercial Gentiana lutea L.

(2015) Ahmed M. Mustafa et al.   FOOD CHEMISTRY

Iridoids and Flavonoids of Four Siberian Gentians: Chemical Profile and Gastric Stimulatory Effect

(2015) Daniil Olennikov et al.   MOLECULES

RETRACTED: Anti-diabetic activity of Swertia corymbosa (Griseb.) Wight ex C.B. Clarke aerial parts extract in streptozotocin induced diabetic rats

(2014) G. Mahendran et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hepatoprotective effects of secoiridoid-rich extracts from Gentiana cruciata L. against carbon tetrachloride induced liver damage in rats

(2014) Vladimir Mihailović et al.   Food & Function

Identification of bio-active metabolites of gentiopicroside by UPLC/Q-TOF MS and NMR

(2013) Wenliang Zeng et al.   BIOMEDICAL CHROMATOGRAPHY

Bullatine A, a diterpenoid alkaloid of the genus Aconitum, could attenuate ATP-induced BV-2 microglia death/apoptosis via P2X receptor pathways

(2013) Jun Li et al.   BRAIN RESEARCH BULLETIN

Role of mitochondrial permeability transition in human hepatocellular carcinoma Hep-G2 cell death induced by rhein

(2013) Qiong Du et al.   FITOTERAPIA

Phytochemical pattern ofGentianaspecies of Appennino in Central Italy

(2013) A. Venditti et al.   NATURAL PRODUCT RESEARCH

Mitochondrial DNA Depletion Syndromes: Review and Updates of Genetic Basis, Manifestations, and Therapeutic Options

(2013) Ayman W. El-Hattab et al.   Neurotherapeutics

Hepatoprotective effects of Gentiana asclepiadea L. extracts against carbon tetrachloride induced liver injury in rats

(2012) Vladimir Mihailović et al.   FOOD AND CHEMICAL TOXICOLOGY

Comparison of the anti-inflammatory and analgesic effects of Gentiana macrophylla Pall. and Gentiana straminea Maxim., and identification of their active constituents

(2012) Na Jia et al.   JOURNAL OF ETHNOPHARMACOLOGY

Microsomal cytochrome P450-mediated metabolism of hypaconitine, an active and highly toxic constituent derived from Aconitum species

(2011) Ling Ye et al.   TOXICOLOGY LETTERS

Involvement of CYP3A4/5 and CYP2D6 in the metabolism of aconitine using human liver microsomes and recombinant CYP450 enzymes

(2011) Lan Tang et al.   TOXICOLOGY LETTERS

Genetic causes of mitochondrial DNA depletion in humans

(2009) Agnès Rötig et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Aconitum in Traditional Chinese Medicine—A valuable drug or an unpredictable risk?

(2009) Judith Singhuber et al.   JOURNAL OF ETHNOPHARMACOLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Extract of the Chinese herbal formula Huo Luo Xiao Ling Dan inhibited adjuvant arthritis in rats

(2008) Rui-Xin Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY