A Preexisting Rare PIK3CA E545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling

标题
A Preexisting Rare PIK3CA E545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling
作者
关键词
-
出版物
Cancer Discovery
Volume 8, Issue 5, Pages 556-567
出版商
American Association for Cancer Research (AACR)
发表日期
2018-03-02
DOI
10.1158/2159-8290.cd-17-0745

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