4.8 Article

D Manganese(II/III/I)-Catalyzed C-H Arylations in Continuous Flow

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ACS CATALYSIS
卷 8, 期 5, 页码 4402-4407

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acscatal.8b00166

关键词

C-H activation; arylation; flow; manganese; mechanism; pyridines

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  1. DFG
  2. CSC

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Versatile manganese-catalyzed C-H arylations on synthetically meaningful pyridines were accomplished with sustainable MnCl2 as the catalyst. The oxidative C-H functionalizations proved viable with a user-friendly and safe continuous flow setup by weak amide-assisted C-H cleavage via a facile C-H activation regime.

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