Article
Chemistry, Multidisciplinary
Yue Wu, Sivan Yakov, Afu Fu, Gilad Yossifon
Summary: This study successfully extends the manipulation and transport capabilities of electrically powered micro- and nanomotors in high-conductivity solutions. By combining magnetic field-based propulsion and navigation with dielectrophoretic manipulation, the micromotors can effectively manipulate and transport various cargos. The ability to identify apoptotic cells and transport live cells to specific regions is demonstrated. This hybrid micromotor approach has significant implications in drug delivery and single-cell analysis.
Review
Chemistry, Physical
Yue Wu, Alicia Boymelgreen, Gilad Yossifon
Summary: This review highlights recent advances in label-free manipulation of cargo by microscale carriers, outlining primary mechanisms and comparing manipulation techniques in terms of selectivity, cargo size, material, and suspending medium. The existing challenges and future prospects are summarized in the conclusion.
CURRENT OPINION IN COLLOID & INTERFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Golak Kunti, Yue Wu, Gilad Yossifon
Summary: Recent studies have focused on electrically powered active particles that can both self-propel and manipulate cargo load and release, with a focus on spherically shaped Janus particles and parallel electrically conducting plates setup. By extending these active carriers to accommodate desired shapes and selective metallic coating using photolithography, controlled dielectrophoretic traps can be designed on them, allowing for sophisticated control over mobility and cargo loading. Additionally, these engineered particles exhibit diverse and rich behaviors compared to spherical JP, showing interesting motion in an electrically insulating substrate setup with in-plane electric field, tilt angle, and even flipping, depending on the field frequency and amplitude.
Article
Biotechnology & Applied Microbiology
Veronica Vespini, Simonetta Grilli, Pietro Ferraro, Romina Rega, Heidi Ottevaere, Yunfeng Nie, Pellegrino Musto, Marianna Pannico
Summary: The pyro-electrohydrodynamic jet printing technology was used to fabricate confined assemblies of gold nanoparticles and evaluated for its surface-enhanced Raman spectroscopy (SERS) performance. The results showed strong plasmonic effects, reproducible signals, and affinity with biomolecules, indicating potential applications in biosensing.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Cell Biology
Jessica J. A. Hummel, Casper C. Hoogenraad
Summary: In this study, the authors systematically investigated the selectivity and regulation of KIF1A-driven transport of different types of vesicles, emphasizing the importance of phosphorylation for vesicle binding and the role of specific adaptors in achieving cargo specificity. They propose a model where motor dimerization, posttranslational modifications, and specific adaptors regulate selective KIF1A cargo trafficking.
JOURNAL OF CELL BIOLOGY
(2021)
Article
Polymer Science
Mikhail Y. Y. Laktionov, Ekaterina B. B. Zhulina, Leonid Klushin, Ralf P. P. Richter, Oleg V. V. Borisov
Summary: Polymer brushes have diverse applications and play crucial roles in biological systems. The binding and movement of colloids on polymer brushes are poorly understood. This study presents a theoretical approach that considers solvent strength and colloid-polymer affinity to analyze colloid transport in planar polymer brushes. The theory provides insights on adjusting brush properties for enhanced selectivity and can aid in designing sensing and purification devices.
MACROMOLECULAR RAPID COMMUNICATIONS
(2023)
Article
Chemistry, Analytical
Lindong Shang, Lei Xu, Yu Wang, Kunxiang Liu, Peng Liang, Shuangjun Zhou, Fuyuan Chen, Hao Peng, Chunyang Zhou, Zhenming Lu, Bei Li
Summary: This article presents a study on the rapid identification of beer spoilage bacteria using surface-enhanced Raman spectroscopy (SERS) technique. By investigating the impact of AgNP concentration and bacterial binding time, eight bacteria species leading to beer spoilage were successfully discovered. The identification accuracy was further improved using machine learning algorithms.
ANALYTICAL METHODS
(2022)
Article
Multidisciplinary Sciences
Jin-Sung Park, Il-Buem Lee, Hyeon-Min Moon, Seok-Cheol Hong, Minhaeng Cho
Summary: Researchers used a label-free interferometric scattering microscope to track cargo transportation in cells and discovered that cells employ strategies similar to human transportation systems to overcome transportation hurdles.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Vaibhav Sharma, Elise Azar, Andre P. Schroder, Carlos M. Marques, Antonio Stocco
Summary: The study reveals that active particles exhibit persistent orbital motion around giant lipid vesicles, independent of the sizes of the particles and vesicles. Additionally, force and torque transfers between the active particles and vesicles are described in the experimental investigation. These findings differ from recent reports on interactions between active particles and solid spheres or liquid drops, and may have implications for understanding the interactions of swimming particles with cells in biology or with microplastics in environmental science.
Article
Physics, Fluids & Plasmas
Alexander R. Sprenger, Christian Bair, Hartmut Loewen
Summary: This paper presents an analytic framework for active Brownian motion with memory delay based on the generalized Langevin equation, assuming time-dependent friction kernels for both translational and orientational degrees of freedom. Analytical results for the orientational correlation function, mean displacement, and mean-square displacement are obtained and evaluated for a Maxwell fluid characterized by an exponentially decaying kernel. The paper also identifies a memory-induced delay between the effective self-propulsion force and the particle orientation, quantified by a special dynamical correlation function. These predictions can be verified experimentally with active colloidal particles in various viscoelastic environments such as polymer solutions.
Article
Physics, Multidisciplinary
Qing Yang, Hongwei Zhu, Peng Liu, Rui Liu, Qingfan Shi, Ke Chen, Ning Zheng, Fangfu Ye, Mingcheng Yang
Summary: The discovery of topological edge states that propagate unidirectionally along the boundary of a system without backscattering has led to new design principles for material or information transport. This study demonstrates that topological edge flow supported by chiral active fluid composed of spinners can robustly transport an immersed intruder through spinner-mediated depletion interaction. The effective interaction depends significantly on the dissipationless odd viscosity of the chiral active fluid, making the transport controllable and proposing a novel avenue for robust cargo transport in biological and microfluidic systems.
PHYSICAL REVIEW LETTERS
(2021)
Article
Chemistry, Physical
Kuntal Patel, Holger Stark
Summary: In recent years, the combination of nonlinear microfluidics and lab-on-a-chip devices has provided new opportunities for chemical and biomedical applications. This article presents a study on the integration of active matter into a microfluidic setting, where active particles generate flows and destabilize the fluid interface, leading to droplet formation. The study utilizes lattice-Boltzmann simulations, phase field dynamics, and advection-diffusion equations to analyze the behavior of the system. The results demonstrate the potential for controlling droplet formation using switchable activity.
Review
Medicine, Research & Experimental
Zhao Cui, Caifeng Li, Peng Chen, Hongjun Yang
Summary: This article reviews the current protein target identification methods for natural active products (NAPs), with a focus on the progress of label-free identification methods.
Review
Chemistry, Multidisciplinary
Eleonora Macchia, Fabrizio Torricelli, Paolo Bollella, Lucia Sarcina, Angelo Tricase, Cinzia Di Franco, Ronald Osterbacka, Zsolt M. Kovacs-Vajna, Gaetano Scamarcio, Luisa Torsi
Summary: Nanometric bioelectronic transducing surfaces have been the main method for detecting single molecules, but are unsuitable for assays at concentrations below the nanomolar level. However, some large-area transistors have shown detection limits lower than femtomolar.
Article
Nanoscience & Nanotechnology
Wendy Xueyi Wang, Travis R. Douglas, Haiwang Zhang, Afrin Bhattacharya, Meghan Rothenbroker, Wentian Tang, Yu Sun, Zhengping Jia, Julien Muffat, Yun Li, Leo Y. T. Chou
Summary: Signal amplification through hybridization chain reaction targets conserved regions of M13mp18 bacteriophage-based scaffold sequences for imaging of unlabelled DNA origami nanostructures. origamiFISH is a label-free and universal method for single-molecule fluorescence detection of DNA origami nanostructures in cells and tissues. It achieves 1,000-fold signal amplification by targeting pan-DN scaffold sequences with hybridization chain reaction probes.
NATURE NANOTECHNOLOGY
(2023)
Article
Chemistry, Physical
Dana Ben-Bassat, Alicia Boymelgreen, Gilad Yossifon
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2015)
Article
Chemistry, Multidisciplinary
Alicia Boymelgreen, Gilad Yossifon
Article
Chemistry, Multidisciplinary
Alicia Boymelgreen, Gilad Yossifon, Touvia Miloh
Article
Physics, Applied
Matan Zehavi, Alicia Boymelgreen, Gilad Yossifon
PHYSICAL REVIEW APPLIED
(2016)
Article
Biochemical Research Methods
Alicia M. Boymelgreen, Touvia Miloh
Article
Physics, Fluids & Plasmas
Alicia Boymelgreen, Gilad Yossifon, Sinwook Park, Touvia Miloh
Article
Mechanics
Alicia M. Boymelgreen, Touvia Miloh
Article
Mechanics
Alicia M. Boymelgreen, Touvia Miloh
Article
Mechanics
Touvia Miloh, Alicia Boymelgreen
Article
Chemistry, Multidisciplinary
Xiaoye Huo, Yue Wu, Alicia Boymelgreen, Gilad Yossifon
Article
Chemistry, Physical
A. M. Boymelgreen, G. Kunti, P. Garcia-Sanchez, A. Ramos, G. Yossifon, T. Miloh
Summary: The study investigates the interaction between active particles and walls to explain discrepancies between experiments and theory. The findings show that the motion direction and frequency dispersion of particles can be controlled by the interaction between ICEP and sDEP. Proximity to walls enhances this interaction and has a significant impact on particle mobility.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Review
Chemistry, Physical
Alicia Boymelgreen, Jarrod Schiffbauer, Boris Khusid, Gilad Yossifon
Summary: The collective motion of synthetic active colloids is a emerging area of research in soft matter physics, which has important implications for fundamental studies and practical applications. Electrokinetic active colloids provide a flexible platform for investigating and modulating collective behavior in active matter.
CURRENT OPINION IN COLLOID & INTERFACE SCIENCE
(2022)
Article
Multidisciplinary Sciences
Preyojon Dey, Terence M. Bradley, Alicia Boymelgreen
Summary: Current studies on the abiotic impacts on Artemia and ecotoxicology often focus on endpoint analysis. This study demonstrates that a mechanistic understanding can be obtained by measuring real-time oxygen consumption in a microfluidic platform. The study shows that different temperatures and salinities significantly alter the duration of hatching stages, metabolic rates, and hatchability.
SCIENTIFIC REPORTS
(2023)
Review
Materials Science, Biomaterials
Vivek Kamat, Preyojon Dey, Dhananjay Bodas, Ajeet Kaushik, Alicia Boymelgreen, Shekhar Bhansali
Summary: Fabricating high-performance nanoparticles with unique properties requires maintaining identical characteristics throughout the processing and application process system. Microfluidic technology provides a unique approach to synthesize nanoparticles with size control, making it suitable for potential biomedical applications. This review discusses various strategies for synthesizing nanoparticles using active microfluidic reactors and explores the challenges and prospects in this field.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
