标题
Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing
作者
关键词
-
出版物
Nature Communications
Volume 9, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-07-02
DOI
10.1038/s41467-018-05073-z
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing
- (2018) Jonathan D. Finn et al. Cell Reports
- Correction of a pathogenic gene mutation in human embryos
- (2017) Hong Ma et al. NATURE
- The chemical evolution of oligonucleotide therapies of clinical utility
- (2017) Anastasia Khvorova et al. NATURE BIOTECHNOLOGY
- Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing
- (2017) Hao Yin et al. NATURE BIOTECHNOLOGY
- Improving CRISPR–Cas specificity with chemical modifications in single-guide RNAs
- (2017) Daniel E Ryan et al. NUCLEIC ACIDS RESEARCH
- Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
- (2016) F. Jiang et al. SCIENCE
- Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
- (2015) Bernd Zetsche et al. CELL
- Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
- (2015) Ayal Hendel et al. NATURE BIOTECHNOLOGY
- A Cas9-guide RNA complex preorganized for target DNA recognition
- (2015) F. Jiang et al. SCIENCE
- Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
- (2014) Hiroshi Nishimasu et al. CELL
- Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease
- (2014) Carolin Anders et al. NATURE
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Immune responses to AAV vectors: overcoming barriers to successful gene therapy
- (2013) F. Mingozzi et al. BLOOD
- DNA targeting specificity of RNA-guided Cas9 nucleases
- (2013) Patrick D Hsu et al. NATURE BIOTECHNOLOGY
- 2′-Fluoro RNA Shows Increased Watson-Crick H-Bonding Strength and Stacking Relative to RNA: Evidence from NMR and Thermodynamic Data
- (2012) Amritraj Patra et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
- (2012) G. Gasiunas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- Unique Gene-Silencing and Structural Properties of 2′-Fluoro-Modified siRNAs
- (2011) Muthiah Manoharan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Tracking genome engineering outcome at individual DNA breakpoints
- (2011) Michael T Certo et al. NATURE METHODS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now