DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis
出版年份 2018 全文链接
标题
DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis
作者
关键词
-
出版物
Nature Communications
Volume 9, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-06-13
DOI
10.1038/s41467-018-04732-5
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Impact of genetic risk loci for multiple sclerosis on expression of proximal genes in patients
- (2018) Tojo James et al. HUMAN MOLECULAR GENETICS
- Graphtyper enables population-scale genotyping using pangenome graphs
- (2017) Hannes P Eggertsson et al. NATURE GENETICS
- Epigenetic research in multiple sclerosis: progress, challenges, and opportunities
- (2017) Galina Y. Zheleznyakova et al. PHYSIOLOGICAL GENOMICS
- Orienting the causal relationship between imprecisely measured traits using GWAS summary data
- (2017) Gibran Hemani et al. PLoS Genetics
- Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations
- (2017) Sigurgeir Olafsson et al. npj Genomic Medicine
- Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation
- (2016) Catherine Do et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells
- (2016) Lu Chen et al. CELL
- The search for the target antigens of multiple sclerosis, part 1: autoreactive CD4+ T lymphocytes as pathogenic effectors and therapeutic targets
- (2016) Reinhard Hohlfeld et al. LANCET NEUROLOGY
- Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation
- (2016) T. F. M. Andlauer et al. Science Advances
- Filter-free exhaustive odds ratio-based genome-wide interaction approach pinpoints evidence for interaction in the HLA region in psoriasis
- (2015) Laura Grange et al. BMC GENETICS
- TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicing
- (2015) R. J. Marina et al. EMBO JOURNAL
- Layered genetic control of DNA methylation and gene expression: a locus of multiple sclerosis in healthy individuals
- (2015) Jean Shin et al. HUMAN MOLECULAR GENETICS
- Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
- (2015) J. Bowden et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- IL-6 blockade by monoclonal antibodies inhibits apolipoprotein (a) expression and lipoprotein (a) synthesis in humans
- (2015) Nike Müller et al. JOURNAL OF LIPID RESEARCH
- Function and information content of DNA methylation
- (2015) Dirk Schübeler NATURE
- Class II HLA interactions modulate genetic risk for multiple sclerosis
- (2015) Loukas Moutsianas et al. NATURE GENETICS
- Large-scale whole-genome sequencing of the Icelandic population
- (2015) Daniel F Gudbjartsson et al. NATURE GENETICS
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Genome-Wide DNA Methylation Profiles Indicate CD8+ T Cell Hypermethylation in Multiple Sclerosis
- (2015) Steffan D. Bos et al. PLoS One
- GeMes, Clusters of DNA Methylation under Genetic Control, Can Inform Genetic and Epigenetic Analysis of Disease
- (2014) Yun Liu et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays
- (2014) Martin J. Aryee et al. BIOINFORMATICS
- Expansion and preferential activation of the CD14+ CD16+ monocyte subset during multiple sclerosis
- (2014) Delgertsetseg Chuluundorj et al. IMMUNOLOGY AND CELL BIOLOGY
- Transcription of Angiogenin and Ribonuclease 4 Is Regulated by RNA Polymerase III Elements and a CCCTC Binding Factor (CTCF)-dependent Intragenic Chromatin Loop
- (2014) Jinghao Sheng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential roles of microglia and monocytes in the inflamed central nervous system
- (2014) Ryo Yamasaki et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Genetic and epigenetic fine mapping of causal autoimmune disease variants
- (2014) Kyle Kai-How Farh et al. NATURE
- Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets
- (2014) Anders H. Olsson et al. PLoS Genetics
- An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform
- (2013) Francesco Marabita et al. Epigenetics
- Genome wide differences of gene expression associated with HLA-DRB1 genotype in multiple sclerosis: A pilot study
- (2013) Michelle L. Apperson et al. JOURNAL OF NEUROIMMUNOLOGY
- Methylation differences at the HLA-DRB1 locus in CD4+ T-Cells are associated with multiple sclerosis
- (2013) MC Graves et al. Multiple Sclerosis Journal
- Nicotine might have a protective effect in the etiology of multiple sclerosis
- (2013) AK Hedström et al. Multiple Sclerosis Journal
- Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
- (2013) Yun Liu et al. NATURE BIOTECHNOLOGY
- Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
- (2013) Ashley H Beecham et al. NATURE GENETICS
- Epigenome-wide differences in pathology-free regions of multiple sclerosis–affected brains
- (2013) Jimmy L Huynh et al. NATURE NEUROSCIENCE
- Multi-Population Classical HLA Type Imputation
- (2013) Alexander Dilthey et al. PLoS Computational Biology
- Common and Low-Frequency Genetic Variants in the PCSK9 Locus Influence Circulating PCSK9 Levels
- (2012) Ekaterina Chernogubova et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- The sva package for removing batch effects and other unwanted variation in high-throughput experiments
- (2012) Jeffrey T. Leek et al. BIOINFORMATICS
- DNA methylation arrays as surrogate measures of cell mixture distribution
- (2012) Eugene Houseman et al. BMC BIOINFORMATICS
- DOGS
- (2012) K. Berger Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz
- Modelling Genetic Susceptibility to Multiple Sclerosis with Family Data
- (2012) Cullen O’Gorman et al. NEUROEPIDEMIOLOGY
- Multiple Sclerosis Risk Variant HLA-DRB1*1501 Associates with High Expression of DRB1 Gene in Different Human Populations
- (2012) Antonio Alcina et al. PLoS One
- Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses
- (2012) R. A. Gottschalk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Swedish Twin Registry: Establishment of a Biobank and Other Recent Developments
- (2012) Patrik K. E. Magnusson et al. Twin Research and Human Genetics
- DNA methylation dysregulates and silences the HLA-DQ locus by altering chromatin architecture
- (2011) P Majumder et al. GENES AND IMMUNITY
- HLA-DRB1*15:01 and multiple sclerosis: a female association?
- (2011) Haritz Irizar et al. Multiple Sclerosis Journal
- A Swedish national post-marketing surveillance study of natalizumab treatment in multiple sclerosis
- (2011) Carolina Holmén et al. Multiple Sclerosis Journal
- CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
- (2011) Sanjeev Shukla et al. NATURE
- Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
- (2011) Stephen Sawcer et al. NATURE
- Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
- (2011) Bahareh Ajami et al. NATURE NEUROSCIENCE
- Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding
- (2010) N. P. Gomes et al. GENES & DEVELOPMENT
- Cohort Profile: The Study of Health in Pomerania
- (2010) H. Volzke et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Autonomous role of medullary thymic epithelial cells in central CD4+ T cell tolerance
- (2010) Maria Hinterberger et al. NATURE IMMUNOLOGY
- Development of Monocytes, Macrophages, and Dendritic Cells
- (2010) F. Geissmann et al. SCIENCE
- Disentangling molecular relationships with a causal inference test
- (2009) Joshua Millstein et al. BMC GENETICS
- An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the HLA-DRB1gene
- (2009) Sreeram V Ramagopalan et al. BMC Medical Genetics
- Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
- (2009) Melanie Bahlo et al. NATURE GENETICS
- Tobacco smoking, but not Swedish snuff use, increases the risk of multiple sclerosis
- (2009) A. K. Hedstrom et al. NEUROLOGY
- The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions
- (2008) Parimal Majumder et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The interleukin 23 receptor gene in multiple sclerosis: A case-control study
- (2008) Izaura M. Roos et al. JOURNAL OF NEUROIMMUNOLOGY
- Detection of sharing by descent, long-range phasing and haplotype imputation
- (2008) Augustine Kong et al. NATURE GENETICS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started