Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2
出版年份 2018 全文链接
标题
Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2
作者
关键词
-
出版物
Cell Death & Disease
Volume 9, Issue 2, Pages -
出版商
Springer Nature
发表日期
2018-02-08
DOI
10.1038/s41419-017-0251-9
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cytoskeletal adaptivity regulates T cell receptor signaling
- (2017) Timothy J. Thauland et al. Science Signaling
- Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis
- (2017) Claire Vennin et al. Science Translational Medicine
- Cytoskeletal adaptivity regulates T cell receptor signaling
- (2017) Timothy J. Thauland et al. Science Signaling
- Rho-Associated Protein Kinase (ROCK) Inhibitors Inhibit Survivin Expression and Sensitize Pancreatic Cancer Stem Cells to Gemcitabine
- (2016) HIROYUKI TAKEDA et al. ANTICANCER RESEARCH
- ABC transporters at the blood–brain barrier
- (2016) Anne Mahringer et al. Expert Opinion on Drug Metabolism & Toxicology
- Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas
- (2016) Simona Daniele et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Role of CD44 and ERM Proteins in Expression and Functionality of P-glycoprotein in Breast Cancer Cells
- (2016) Deep Pokharel et al. MOLECULES
- Cancer Stem Cells and Radioresistance: Rho/ROCK Pathway Plea Attention
- (2016) Annapurna Pranatharthi et al. Stem Cells International
- Oct-3/4 modulates the drug-resistant phenotype of glioblastoma cells through expression of ATP binding cassette transporter G2
- (2015) Yuki Hosokawa et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- RhoGTPases – A novel link between cytoskeleton organization and cisplatin resistance
- (2015) Daphna Mokady et al. DRUG RESISTANCE UPDATES
- Rho Kinase (ROCK) Inhibitors and Their Therapeutic Potential
- (2015) Yangbo Feng et al. JOURNAL OF MEDICINAL CHEMISTRY
- Abnormal Wnt signaling and overexpression of ABCG2 contributes to drug efflux properties of side population cells in nasopharyngeal carcinoma
- (2015) GUO-FANG GUAN et al. Molecular Medicine Reports
- Multidrug Efflux Pumps Attenuate the Effect of MGMT Inhibitors
- (2015) Karl-Heinz Tomaszowski et al. MOLECULAR PHARMACEUTICS
- Role of Scaffold Proteins in Functional Alteration of Small Intestinal P-glycoprotein by Anti-cancer Drugs
- (2015) Takuro Kobori et al. YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
- Inhibition of multidrug resistance protein 1 (MRP1) improves chemotherapy drug response in primary and recurrent glioblastoma multiforme
- (2015) Amanda Tivnan et al. Frontiers in Neuroscience
- ROCK Inhibition Facilitates In Vitro Expansion of Glioblastoma Stem-Like Cells
- (2015) Samantha G. Tilson et al. PLoS One
- ABCB1, ABCG2, and PTEN Determine the Response of Glioblastoma to Temozolomide and ABT-888 Therapy
- (2014) F. Lin et al. CLINICAL CANCER RESEARCH
- ABC transporters as differentiation markers in glioblastoma cells
- (2014) Ana R. Rama et al. MOLECULAR BIOLOGY REPORTS
- Temozolomide Induces the Production of Epidermal Growth Factor to Regulate MDR1 Expression in Glioblastoma Cells
- (2014) J. L. Munoz et al. MOLECULAR CANCER THERAPEUTICS
- Downregulation of ROCK2 through Nanocomplex Sensitizes the Cytotoxic Effect of Temozolomide in U251 Glioma Cells
- (2014) Xiaojun Wen et al. PLoS One
- Differential role of P-glycoprotein and breast cancer resistance protein in drug distribution into brain, CSF and peripheral nerve tissues in rats
- (2014) Liyue Huang et al. XENOBIOTICA
- Ocular hypotensive efficacy, safety and systemic absorption of AR-12286 ophthalmic solution in normal volunteers
- (2013) Casey Kopczynski et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Time-Dependent Changes in the Activation of RhoA/ROCK and ERM/p-ERM in the Increased Expression of Intestinal P-Glycoprotein by Repeated Oral Treatment with Etoposide
- (2013) Takuro Kobori et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme
- (2013) Leroi V DeSouza et al. Molecular Cancer
- Activated ERM Protein Plays a Critical Role in Drug Resistance of MOLT4 Cells Induced by CCL25
- (2013) Li Zhang et al. PLoS One
- Temozolomide-related idiosyncratic and other uncommon toxicities
- (2012) Sanjay Dixit et al. ANTI-CANCER DRUGS
- Inhibition of the Rho/ROCK pathway enhances the efficacy of cisplatin through the blockage of hypoxia-inducible factor-1α in human ovarian cancer cells
- (2012) Tsuyoshi Ohta et al. CANCER BIOLOGY & THERAPY
- Moesin Is a Glioma Progression Marker That Induces Proliferation and Wnt/ -Catenin Pathway Activation via Interaction with CD44
- (2012) X. Zhu et al. CANCER RESEARCH
- Study of chemoresistant CD133+ cancer stem cells from human glioblastoma cell line U138MG using multiple assays
- (2012) Sudha Warrier et al. CELL BIOLOGY INTERNATIONAL
- Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy
- (2011) X. Gong et al. NEUROLOGY
- Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity
- (2010) Mutsuki Amano et al. Cytoskeleton
- Fasudil Inhibits Lysophosphatidic Acid-Induced Invasiveness of Human Ovarian Cancer Cells
- (2010) Seiji Ogata et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Overexpression of CD133 Promotes Drug Resistance in C6 Glioma Cells
- (2010) J. M. Angelastro et al. MOLECULAR CANCER RESEARCH
- HDMX regulates p53 activity and confers chemoresistance to 3-Bis(2-chloroethyl)-1-nitrosourea
- (2010) Genglin Jin et al. NEURO-ONCOLOGY
- EGFRvIII and DNA Double-Strand Break Repair: A Molecular Mechanism for Radioresistance in Glioblastoma
- (2009) B. Mukherjee et al. CANCER RESEARCH
- Lack of ABCG2 Expression and Side Population Properties in Human Pluripotent Stem Cells
- (2009) Hui Zeng et al. STEM CELLS
- Cytoskeleton and apoptosis
- (2008) Olivia Ndozangue-Touriguine et al. BIOCHEMICAL PHARMACOLOGY
- ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier
- (2008) Sandrine Dauchy et al. JOURNAL OF NEUROCHEMISTRY
- Evidence of galectin-1 involvement in glioma chemoresistance☆
- (2008) Marie Le Mercier et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Mechanisms of Disease: temozolomide and glioblastoma—look to the future
- (2008) Maciej M Mrugala et al. Nature clinical practice. Oncology
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