Review
Nutrition & Dietetics
Gholamreza Askari, Abed Ghavami, Farnaz Shahdadian, Amir Reza Moravejolahkami
Summary: The study found that supplementation with synbiotics and probiotics has a significant effect on certain inflammatory and oxidative stress markers, but further research is needed to confirm these findings.
CLINICAL NUTRITION
(2021)
Review
Biochemistry & Molecular Biology
Pablo Salmon, Pablo Burraco
Summary: Human-driven environmental changes are impacting wildlife, but the extent of their impact varies among different species. Telomere length has been proposed as a potential biomarker for animal health and fitness, but its use in ecological studies is limited. A systematic review and meta-analysis found a small negative association between anthropogenic disturbances and telomere length in wild animals. However, further research is needed to fully understand the causal relationship and implications of telomere length in anthropogenically disturbed scenarios.
Review
Immunology
Arduino A. Mangoni, Angelo Zinellu
Summary: This study evaluated the pathophysiological role of neopterin in patients with rheumatic diseases through systematic review and meta-analysis. The results showed that neopterin concentrations were significantly higher in patients with RD compared to healthy controls. However, there were no significant associations found between neopterin concentrations and factors such as age and gender ratio, but associations were observed with geographical area and type of RD.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Multidisciplinary Sciences
Manas Kotepui, Aongart Mahittikorn, Nsoh Godwin Anabire, Kwuntida Uthaisar Kotepui
Summary: This meta-analysis study found that blood levels of GPx were significantly decreased in malaria patients, especially in those with P. falciparum malaria. This finding provides important insights for further investigation into the role of GPx depletion in malaria pathogenesis.
SCIENTIFIC REPORTS
(2023)
Review
Biochemistry & Molecular Biology
Maria Carmina Pau, Elisabetta Zinellu, Sara S. Fois, Barbara Piras, Gianfranco Pintus, Ciriaco Carru, Arduino A. Mangoni, Alessandro G. Fois, Angelo Zinellu, Pietro Pirina
Summary: The study found that the MDA concentrations were significantly higher in patients with obstructive sleep apnea (OSA) compared to controls, indicating that MDA may be involved in the pathogenesis of OSA and providing insights for future research on its potential clinical use.
Review
Environmental Sciences
Weidong Hu, Zhengke He, Lin Du, Li Zhang, Jun Li, Yue Ma, Shicheng Bi
Summary: The aim of this study was to evaluate the effect of LPS exposure on OS-associated markers. The results showed that LPS treatment significantly increased the levels of oxygen radicals and their products, while significantly reducing the levels of antioxidants. Subgroup evaluation revealed that the jejunum and duodenum demonstrated stronger antioxidant capability. Overall, exposure to LPS induces significant OS in chickens.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Review
Medicine, General & Internal
Fanwen Jiang, Lin Zhou, Chun Zhang, Hui Jiang, Zhuping Xu
Summary: This systematic review compared circulating malondialdehyde (MDA) levels in people with and without diabetic retinopathy (DR). The results showed that circulating MDA levels were higher in people with DR compared to those without.
CHINESE MEDICAL JOURNAL
(2023)
Review
Multidisciplinary Sciences
Jalal Bohlouli, Iman Namjoo, Mohammad Borzoo-Isfahani, Mohammad Ali Hojjati Kermani, Zakiyeh Balouch Zehi, Amir Reza Moravejolahkami
Summary: Probiotics have been shown to significantly reduce hs-CRP and MDA levels, while increasing GSH and TAC levels in patients with Diabetic Nephropathy. This suggests that probiotics may have a beneficial effect on inflammation and oxidative stress in this population.
Review
Respiratory System
Shuyuan Yang, Gengze Liao, Lap Ah Tse
Summary: This systematic review found that individuals with PRISm have a higher risk of all-cause, cardiovascular, and respiratory-related mortality compared with those with normal spirometry.
EUROPEAN RESPIRATORY REVIEW
(2023)
Review
Biochemistry & Molecular Biology
Qiong Yu, Fengyu Xue, Zhijun Li, Xinwei Li, Lizhe Ai, Mengdi Jin, Mengtong Xie, Yaqin Yu
Summary: Through a meta-analysis of multiple studies, it was found that the intake of total carotenoids, beta-carotene, alpha-carotene, lycopene, and/or corn xanthin was significantly inversely associated with depressive symptoms, while beta-cryptoxanthin showed no significant correlation. The results suggest that carotenoids may act as protective factors for depressive symptoms, and dietary intake may help reduce the risk of depressive symptoms.
Review
Biochemistry & Molecular Biology
Maria Carmina Pau, Arduino Aleksander Mangoni, Elisabetta Zinellu, Gianfranco Pintus, Ciriaco Carru, Alessandro Giuseppe Fois, Pietro Pirina, Angelo Zinellu
Summary: The study found that whole blood SOD concentrations were significantly lower in patients with obstructive sleep apnoea, while serum/plasma SOD concentrations did not show a significant difference. This suggests an impaired antioxidant defence in OSA patients.
Review
Cardiac & Cardiovascular Systems
Andrea Faggiano, Elisa Gherbesi, Ashot Avagimyan, Massimiliano Ruscica, Luca Donisi, Maria Antonia Fedele, Carlo Maria Cipolla, Marco Vicenzi, Stefano Carugo, Daniela Cardinale
Summary: Melatonin can mitigate the oxidative damage induced by anthracycline in a mouse model, demonstrating its potential as a preventive and therapeutic strategy for anthracycline-induced cardiotoxicity.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Zhanyi Zhou, Chaoyi Chen, Ee-Chon Teo, Yan Zhang, Jialu Huang, Yining Xu, Yaodong Gu
Summary: Exercise programs can improve an individual's antioxidative capacity, but inappropriate programs can induce oxidative stress. The severity of oxidative stress depends on the intensity and volume of exercise, as well as the individual's health condition. Recommendations include continuous aerobic exercise under moderate intensity or high-intensity interval training to enhance the body's redox balance, especially for unhealthy individuals.
Review
Biochemistry & Molecular Biology
Sawan Ali, Graziamaria Corbi, Michael Maes, Giovanni Scapagnini, Sergio Davinelli
Summary: The latest evidence suggests that dietary flavonoids have a significant effect on improving symptoms of depression, with higher intake of flavonoids potentially beneficial for alleviating depressive symptoms. Further research is needed to clarify the causal and mechanistic links, as well as confirm the functional brain changes associated with flavonoid consumption.
Review
Medicine, General & Internal
Mohammad Mohammadi, Adeleh Yarmohammadi, Amin Salehi-Abargouei, Hamidreza Ghasemirad, Mohammad Shirvani, Hamed Ghoshouni
Summary: A meta-analysis was conducted to investigate the association between serum uric acid (UA) level and glaucoma. The findings suggested that glaucoma patients have a higher serum UA level compared to the controls, but this difference was not statistically significant. Further prospective studies are needed to determine the potential association between increased UA and glaucoma pathogenesis.
FRONTIERS IN MEDICINE
(2023)
Article
Endocrinology & Metabolism
Elnaz Daneshzad, Farzaneh Jahangir, Javad Heshmati, Bagher Larijani, Pamela J. Surkan, Leila Azadbakht
Summary: The study indicates that plant-based dietary indices and dietary acid load are not associated with cardiovascular disease risk factors among type 2 diabetic women.
INTERNATIONAL JOURNAL OF DIABETES IN DEVELOPING COUNTRIES
(2021)
Article
Plant Sciences
Javad Heshmati, Ashraf Moini, Mahdi Sepidarkish, Mojgan Morvaridzadeh, Masoud Salehi, Andriko Palmowski, Maryam Farid Mojtahedi, Farzad Shidfar
Summary: The study found that using curcumin in PCOS patients can effectively improve blood sugar and androgen levels, and is safe and reliable. Longer trials with different dosages are needed to confirm these findings.
Review
Biochemistry & Molecular Biology
Mojgan Morvaridzadeh, Ehsan Sadeghi, Shahram Agah, Siavash Fazelian, Mehran Rahimlou, Ferdinand Georg Kern, Shilan Heshmati, Amirhosein Omidi, Emma Persad, Javad Heshmati
Summary: The study provides convincing evidence supporting the efficacy of ginger supplementation in improving oxidative stress levels, including an increase in antioxidant enzyme activity and total antioxidant capacity, as well as a decrease in malondialdehyde levels.
JOURNAL OF FOOD BIOCHEMISTRY
(2021)
Article
Obstetrics & Gynecology
Rona Akefi, Seyed Mojtaba Hashemi, Saeed Alinejad, Amir Almasi-Hashiani
Summary: This study aimed to investigate the effect of UDCA in treating neonates with unconjugated hyperbilirubinemia undergoing phototherapy. The results showed that UDCA combined with phototherapy enhanced the decrease in total bilirubin level, but it did not decrease the duration of phototherapy and hospital stay from a clinical point of view.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Medicine, Research & Experimental
Mojtaba Kaviani, Azimeh Izadi, Javad Heshmati
Summary: Low carbohydrate high fat (LCHF) diets are effective for weight and fat mass loss, but may impair maximal and supramaximal exercise performance. Creatine supplementation can increase muscle power output and reduce fatigue, potentially improving body composition. Combining creatine with LCHF diets may lead to enhanced fat loss and better body composition.
MEDICAL HYPOTHESES
(2021)
Review
Food Science & Technology
Mahdi Sepidarkish, Gholamreza Rezamand, Mostafa Qorbani, Hafez Heydari, M. Dulce Estevao, Dalia Omran, Mojgan Morvaridzadeh, Darren M. Roffey, Farnaz Farsi, Sara Ebrahimi, Fatemeh Shokri, Javad Heshmati
Summary: The intake of OMEGA-3 FAs has a positive impact on plasma adiponectin levels but does not significantly affect leptin levels. Larger, well-designed randomized controlled trials are needed to evaluate the effect of OMEGA-3 FAs on leptin levels in specific diseases.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Medicine, General & Internal
Saeid Safiri, Mark J. M. Sullman, Timo Lajunen, Tetiana Hill, Amir Almasi-Hashiani, Maziar Moradi-Lakeh, Farshad Farzadfar, Sadaf G. Sepanlou, Eman Abu-Gharbieh, Teamur Aghamolaei, Tauseef Ahmad, Suliman A. Alghnam, Samar Al-Hajj, Vahid Alipour, Syed Mohamed Aljunid, Mina Anjomshoa, Alireza Ansari-Moghaddam, Jalal Arabloo, Mohsen Bayati, Neeraj Bedi, Salaheddine Bendak, Zulfiqar A. Bhutta, Ali Bijani, Saad M. A. Dahlawi, Mostafa Dianatinasab, Zahra Sadat Dibaji Forooshani, Hala Rashad Elhabashy, Amir Emami Zeydi, Sharareh Eskandarieh, Mansour Ghafourifard, Ahmad Ghashghaee, Michal Grivna, Mohammed Ibrahim Mohialdeen Gubari, Randah R. Hamadeh, Samer Hamidi, Khezar Hayat, Enayatollah Homaie Rad, Mehdi Hosseinzadeh, Mowafa Househ, Seyed Sina Naghibi Irvani, Mohammad Ali Jahani, Leila R. Kalankesh, Rohollah Kalhor, Ibrahim Kamel, Mohammad Khammarnia, Maseer Khan, Habibolah Khazaie, Hamidreza Komaki, Amitis Lahimchi, Mohammed Madadin, Shokofeh Maleki, Navid Manafi, Fariborz Mansour-Ghanaei, Mohammad Ali Mansournia, Ritesh G. Menezes, Yousef Mohammad, Abdollah Mohammadian-Hafshejani, Farnam Mohebi, Ghobad Moradi, Rahmatollah Moradzadeh, Seyyed Meysam Mousavi, Mehdi Naderi, Rajan Nikbakhsh, Keyvan Pakshir, Akram Pourshams, Navid Rabiee, Alireza Rafiei, Reza Rawassizadeh, Aziz Rezapour, Basema Saddik, Sahar Saeedi Moghaddam, Payman Salamati, Marwa Rashad Salem, Hosni Salem, Abdallah M. Samy, Brijesh Sathian, Saeed Shahabi, Masood Ali Shaikh, Mehran Shams-Beyranvand, Morteza Shamsizadeh, Mohammad Reza Sobhiyeh, Amin Soheili, Arash Tehrani-Banihashemi, Yasir Waheed, Hasan Yusefzadeh, Telma Zahirian Moghadam, Leila Zaki, Mohammad Zamani, Hamed Zandian, Reza Malekzadeh, Mohsen Naghavi
Summary: Although the rates of incidence and death in the Eastern Mediterranean region (EMR) were relatively lower in 2017, the number of transport-related fatalities is increasing. There are significant differences in mortality rates among different countries, highlighting the urgent need for action.
ARCHIVES OF IRANIAN MEDICINE
(2021)
Article
Medical Informatics
Emma Nichols, Foad Abd-Allah, Amir Abdoli, Ahmed Abualhasan, Eman Abu-Gharbieh, Ashkan Afshin, Rufus Olusola Akinyemi, Fahad Mashhour Alanezi, Vahid Alipour, Amir Almasi-Hashiani, Jalal Arabloo, Amir Ashraf-Ganjouei, Getinet Ayano, Jose L. Ayuso-Mateos, Atif Amin Baig, Maciej Banach, Miguel A. Barboza, Suzanne Lyn Barker-Collo, Bernhard T. Baune, Akshaya Srikanth Bhagavathula, Krittika Bhattacharyya, Ali Bijani, Atanu Biswas, Archith Boloor, Carol Brayne, Hermann Brenner, Katrin Burkart, Sharath Burugina Nagaraja, Felix Carvalho, Luis F. S. Castro-de-Araujo, Ferran Catala-Lopez, Ester Cerin, Nicolas Cherbuin, Dinh-Toi Chu, Xiaochen Dai, Antonio Reis De Sa-Junior, Shirin Djalalinia, Abdel Douiri, David Edvardsson, Shaimaa El-Jaafary, Sharareh Eskandarieh, Andre Faro, Farshad Farzadfar, Valery L. Feigin, Seyed-Mohammad Fereshtehnejad, Eduarda Fernandes, Pietro Ferrara, Irina Filip, Florian Fischer, Shilpa Gaidhane, Lucia Galluzzo, Gebreamlak Gebremedhn Gebremeskel, Ahmad Ghashghaee, Alessandro Gialluisi, Elena Gnedovskaya, Mahaveer Golechha, Rajeev Gupta, Vladimir Hachinski, Mohammad Rifat Haider, Teklehaimanot Gereziher Haile, Mohammad Hamiduzzaman, Graeme J. Hankey, Simon Hay, Golnaz Heidari, Reza Heidari-Soureshjani, Hung Chak Ho, Mowafa Househ, Bing-Fang Hwang, Licia Iacoviello, Olayinka Stephen Ilesanmi, Irena M. Ilic, Milena D. Ilic, Seyed Sina Naghibi Irvani, Masao Iwagami, Ihoghosa Osamuyi Iyamu, Ravi Prakash Jha, Rizwan Kalani, Andre Karch, Ayele Semachew Kasa, Yousef Saleh Khader, Ejaz Ahmad Khan, Mahalaqua Nazli Khatib, Yun Jin Kim, Sezer Kisa, Adnan Kisa, Mika Kivimaki, Ai Koyanagi, Manasi Kumar, Ivan Landires, Savita Lasrado, Bingyu Li, Stephen S. Lim, Xuefeng Liu, Shilpashree Madhava Kunjathur, Azeem Majeed, Preeti Malik, Man Mohan Mehndiratta, Ritesh G. Menezes, Yousef Mohammad, Salahuddin Mohammed, Ali H. Mokdad, Mohammad Ali Moni, Gabriele Nagel, Muhammad Naveed, Vinod C. Nayak, Cuong Tat Nguyen, Huong Lan Thi Nguyen, Virginia Nunez-Samudio, Andrew T. Olagunju, Samuel M. Ostroff, Nikita Otstavnov, Mayowa O. Owolabi, Fatemeh Pashazadeh Kan, Urvish K. Patel, Michael R. Phillips, Michael A. Piradov, Constance Dimity Pond, Faheem Hyder Pottoo, Sergio Prada, Amir Radfar, Fakher Rahim, Juwel Rana, Vahid Rashedi, Salman Rawaf, David Laith Rawaf, Nickolas Reinig, Andre M. N. Renzaho, Nima Rezaei, Aziz Rezapour, Michele Romoli, Gholamreza Roshandel, Perminder S. Sachdev, Amirhossein Sahebkar, Mohammad Ali Sahraian, Mehrnoosh Samaei, Mete Saylan, Feng Sha, Masood Ali Shaikh, Kenji Shibuya, Mika Shigematsu, Jae Il Shin, Rahman Shiri, Diego Augusto Santos Silva, Jasvinder A. Singh, Deepika Singhal, Valentin Yurievich Skryabin, Anna Aleksandrovna Skryabina, Amin Soheili, Houman Sotoudeh, Emma Elizabeth Spurlock, Cassandra E. Szoeke, Rafael Tabares-Seisdedos, Biruk Wogayehu Taddele, Marcos Roberto Tovani-Palone, Gebiyaw Wudie Tsegaye, Marco Vacante, Narayanaswamy Venketasubramanian, Simone Vidale, Vasily Vlassov, Giang Thu Vu, Yuan-Pang Wang, Jordan Weiss, Abrha Hailay Weldemariam, Ronny Westerman, Anders Wimo, Andrea Sylvia Winkler, Chenkai Wu, Ali Yadollahpour, Metin Yesiltepe, Naohiro Yonemoto, Chuanhua Yu, Mikhail Sergeevich Zastrozhin, Anasthasia Zastrozhina, Zhi-Jiang Zhang, Christopher J. L. Murray, Theo Vos
Summary: Data sparsity is a major limitation for estimating dementia burden on a national and global level. This study developed an algorithm using validation samples from nationally representative surveys to predict dementia prevalence. By classifying dementia status based on cognition and function scores, the algorithm was able to accurately estimate dementia prevalence across different age and gender groups.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2021)
Article
Clinical Neurology
Payam Amini, Amir Almasi-Hashiani, Mohammad Ali Sahraian, Masood Najafi, Sharareh Eskandarieh
Summary: This study found that the prevalence of MS has been increasing in Tehran over the past three decades, and is expected to continue to rise in the next ten years. Females have a higher risk for MS compared to males in both familial and sporadic cases.
Article
Public, Environmental & Occupational Health
Amir Almasi-Hashiani, Saharnaz Nedjat, Reza Ghiasvand, Saeid Safiri, Maryam Nazemipour, Nasrin Mansournia, Mohammad Ali Mansournia
Summary: Postmenopausal women, women with a higher age at first marriage, shorter duration of breastfeeding, and history of oral contraceptive use are at higher risk of breast cancer.
Review
Food Science & Technology
Mojgan Morvaridzadeh, Shahram Agah, M. Dulce Estevao, Ava Sadat Hosseini, Hafez Heydari, Omid Toupchian, Shima Abdollahi, Emma Persad, Ahmed Abu-Zaid, Gholamreza Rezamand, Javad Heshmati
Summary: Studies have shown that saffron supplementation can significantly decrease malondialdehyde levels and increase total antioxidant capacity in unhealthy patients, indicating its beneficial properties in improving oxidative stress. However, additional randomized controlled trials are needed to evaluate the effects on other oxidative stress parameters.
FOOD SCIENCE & NUTRITION
(2021)
Article
Psychiatry
Elnaz Daneshzad, Maryam Mansordehghan, Bagher Larijani, Javad Heshmati, Tohid Rouzitalab, Ana Beatriz Pizarro, Leila Azadbakht
Summary: This study on 230 Tehrani women with type 2 diabetes found that patients with higher adherence to diet quality indices were less likely to have mental disorders or poor sleep.
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2022)
Article
Geography
Mahmood Vasegh, Ahad Mohammadi, Javad Heshmati
Summary: In contrast to structuralists, who aimed for a fixed framework of meanings, post-structuralists believed that knowledge is not constrained by fixed structures and meanings, but rather fluctuates and evolves through a continuous process of semantic dialectics. In the field of geography, meanings are produced in the communication between spaces, and there are no independent meanings and identities for geographical space and place alone. The authors of this article argue that post-structuralism is a non-scientific and non-epistemic viewpoint, and it has conceptual and epistemic contradictions.
Article
Endocrinology & Metabolism
Amir Kasaeian, Zeinab Hemati, Ramin Heshmat, Fereshteh Bayegi, Javad Heshmati, Armita Mahdavi-Gorabi, Mohammad Esmaeili Abdar, Mohammad Esmaeil Motlagh, Gita Shafiee, Mostafa Qorban, Roya Kelishadi
Summary: The study found a significant association between body shape index (ABSI) and hip index (HI) with cardiometabolic risk factors (CMRFs), suggesting that these indices can be useful anthropometric risk indicators for predicting metabolic syndrome (MetS).
JOURNAL OF DIABETES AND METABOLIC DISORDERS
(2021)
Review
Biochemistry & Molecular Biology
Javad Heshmati, Mahdi Sepidarkish, Mojgan Morvaridzadeh, Farnaz Farsi, Nishant Tripathi, Maryam Razavi, Mahroo Rezaeinejad
Summary: This study included 5 RCTs and found that cinnamon supplementation significantly reduced insulin resistance scores in women with PCOS and may improve certain IR markers. Cinnamon is suggested to lower IR by promoting insulin action, stimulating insulin signaling pathways, and enhancing insulin sensitivity.
JOURNAL OF FOOD BIOCHEMISTRY
(2021)
