Mass and charge distributions of amyloid fibers involved in neurodegenerative diseases: mapping heterogeneity and polymorphism

Single Particle Analyzer of Mass: A Charge Detection Mass Spectrometer with a Multi-Detector Electrostatic Ion Trap

(2017) Andrew G. Elliott et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes

(2017) Wei Qiang et al.   NATURE

Resolving Adeno-Associated Viral Particle Diversity With Charge Detection Mass Spectrometry

(2016) Elizabeth E. Pierson et al.   ANALYTICAL CHEMISTRY

Polymorphism of Amyloid Fibrils In Vivo

(2016) Karthikeyan Annamalai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Native Mass Spectrometry: What is in the Name?

(2016) Aneika C. Leney et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Catching a virus in a molecular net

(2016) L. Delalande et al.   Nanoscale

Measurement of the accurate mass of a 50 MDa infectious virus

(2016) David Z. Keifer et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

MpUL-multi: Software for Calculation of Amyloid Fibril Mass per Unit Length from TB-TEM Images

(2016) Matthew G. Iadanza et al.   Scientific Reports

Quantitative thermophoretic study of disease-related protein aggregates

(2016) Manuel Wolff  et al.   Scientific Reports

Competition between Primary Nucleation and Autocatalysis in Amyloid Fibril Self-Assembly

(2015) Kym Eden et al.   BIOPHYSICAL JOURNAL

Tau in physiology and pathology

(2015) Yipeng Wang et al.   NATURE REVIEWS NEUROSCIENCE

Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled A , tau, and  -synuclein

(2015) M. Goedert   SCIENCE

Amyloid Fibres: Inert End-Stage Aggregates or Key Players in Disease?

(2015) Kevin W. Tipping et al.   TRENDS IN BIOCHEMICAL SCIENCES

SDS-PAGE analysis of Aβ oligomers is disserving research into Alzheimer´s disease: appealing for ESI-IM-MS

(2015) Rosa Pujol-Pina et al.   Scientific Reports

Charge Detection Mass Spectrometry for the Characterization of Mass and Surface Area of Composite Nanoparticles

(2014) Tristan Doussineau et al.   Journal of Physical Chemistry C

Detection of Late Intermediates in Virus Capsid Assembly by Charge Detection Mass Spectrometry

(2014) Elizabeth E. Pierson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Boundaries of Mass Resolution in Native Mass Spectrometry

(2014) Philip Lössl et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Solution conditions determine the relative importance of nucleation and growth processes in  -synuclein aggregation

(2014) A. K. Buell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Charge detection mass spectrometry of bacteriophage P22 procapsid distributions above 20 MDa

(2014) David Z. Keifer et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

A Clear View of Polymorphism, Twist, and Chirality in Amyloid Fibril Formation

(2013) Lisa R. Volpatti et al.   ACS Nano

Studying 18 MDa Virus Assemblies with Native Mass Spectrometry

(2013) Joost Snijder et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel Mechanistic Insight into the Molecular Basis of Amyloid Polymorphism and Secondary Nucleation during Amyloid Formation

(2013) Jae Sun Jeong et al.   JOURNAL OF MOLECULAR BIOLOGY

Correlation between the Charge of Polymer Particles in Solution and in the Gas Phase Investigated by Zeta-Potential Measurements and Electrospray Ionization Mass Spectrometry.

(2013) Nesrine Ouadah et al.   LANGMUIR

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

(2013) Mathias Jucker et al.   NATURE

Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism

(2013) S. I. A. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

The fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush

(2012) Susanne Wegmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Dynamic Structure of Filamentous Tau

(2011) Stefan Bibow et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Understanding the Kinetic Roles of the Inducer Heparin and of Rod-like Protofibrils during Amyloid Fibril Formation by Tau Protein

(2011) Gayathri Ramachandran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Charging megadalton poly(ethylene oxide)s by electrospray ionization. A charge detection mass spectrometry study

(2011) Tristan Doussineau et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Size-dependent neurotoxicity of β-amyloid oligomers

(2010) Paulius Cizas et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Current limitations in native mass spectrometry based structural biology

(2010) Esther Duijn   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Ion mobility–mass spectrometry reveals a conformational conversion from random assembly to β-sheet in amyloid fibril formation

(2010) Christian Bleiholder et al.   Nature Chemistry

Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils

(2010) Mahiuddin Ahmed et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alzheimer's Disease: From Pathology to Therapeutic Approaches

(2009) Roland Jakob-Roetne et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

(2009) Summer L. Bernstein et al.   Nature Chemistry

Experimental characterization of disordered and ordered aggregates populated during the process of amyloid fibril formation

(2009) N. Carulla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of Alzheimer A (1-40) and A (1-42) amyloid fibrils reveals similar protofilament structures

(2009) M. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Analytical Solution to the Kinetics of Breakable Filament Assembly

(2009) T. P. J. Knowles et al.   SCIENCE

Aβ(1-40) Fibril Polymorphism Implies Diverse Interaction Patterns in Amyloid Fibrils

(2008) Jessica Meinhardt et al.   JOURNAL OF MOLECULAR BIOLOGY

Native mass spectrometry: a bridge between interactomics and structural biology

(2008) Albert J R Heck   NATURE METHODS

High-resolution mass spectrometry of viral assemblies: Molecular composition and stability of dimorphic hepatitis B virus capsids

(2008) C. Uetrecht et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Average protein density is a molecular-weight-dependent function

(2004) Hannes Fischer et al.   PROTEIN SCIENCE