Review
Immunology
Zhuanzhuan Liu, Qingxin Zhang, Liya Li, Junjie He, Jinyang Guo, Zichen Wang, Yige Huang, Zimeng Xi, Fei Yuan, Yiji Li, Tingting Li
Summary: This review explores the correlations between temperature and dengue epidemics, including the distribution and development of Aedes mosquitoes, the structure of DENV, and the vector competence of Aedes mosquitoes. Additionally, it discusses the immune and metabolic mechanism through which temperature affects the vector competence of Aedes mosquitoes to transmit DENV.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Parasitology
Lie Cheng, Wei-Liang Liu, Matthew P. Su, Shu-Chen Huang, Jen-Ren Wang, Chun-Hong Chen
Summary: In this study, we found that prohemocytes were the major type of hemocyte infected by DENV in both Ae. aegypti and Ae. albopictus. The infection rate of prohemocytes in Ae. albopictus was lower than that in Ae. aegypti, which may explain why systemic DENV infection in Ae. albopictus is less efficient than in Ae. aegypti and why Ae. albopictus is less correlated to dengue fever outbreaks.
PARASITES & VECTORS
(2022)
Article
Entomology
Jameel M. Abduljalil, Fahd M. Abd Al Galil
Summary: Deciphering the molecular interactions between DENV and its vector is a promising field to develop efficient control strategies for DENV.
JOURNAL OF INSECT PHYSIOLOGY
(2022)
Article
Microbiology
Teng Zhao, Bo-qi Li, He-ting Gao, Dan Xing, Man-jin Li, Yun-qi Dang, Heng-duan Zhang, Yue-e Zhao, Zhu Liu, Chun-xiao Li
Summary: This study sequenced the microbiome of Aedes albopictus before and after exposure to DENV blood meal, and found significant variation in the microbiome composition. Several microorganisms related to mosquito immunity and metabolism were identified. The study suggests that intervention in the microbiome or specific bacteria of A. albopictus could potentially control DENV transmission.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Biochemical Research Methods
Yuliang Chen, Tao Liu, Xiaolin Yu, Qinghui Zeng, Zixi Cai, Haisheng Wu, Qingying Zhang, Jianpeng Xiao, Wenjun Ma, Sen Pei, Pi Guo
Summary: This study proposes an ensemble forecast system for dengue fever, which addresses the challenge of predicting outbreaks with different scales. By combining a susceptible-infected-recovered (SIR) model with the ensemble adjusted Kalman filter (EAKF) algorithm, the system generates real-time forecasts of dengue fever spread dynamics and adjusts the predicted outbreak size based on updated information. The system outperforms a generalized additive model approach in accurately projecting peak timing, peak intensity, and total incidence in retrospective forecasts of dengue outbreaks in Guangzhou, China.
PLOS COMPUTATIONAL BIOLOGY
(2022)
Article
Agronomy
Tong Liu, Yu-Gu Xie, Feng Lin, Li-Hua Xie, Wen-Qiang Yang, Xing-Hua Su, Chun-Quan Ou, Lei Luo, Qi Xiao, Lu Gan, Xiao-Guang Chen
Summary: The study successfully developed a long-lasting biological larvicide called Bti-BLOCK, which demonstrated good efficacy in controlling the dengue vector mosquito Ae. albopictus in both laboratory and field experiments. Bti-BLOCK slowly released insecticidal toxins, maintaining effective dose for up to 6 months, lasting for at least 12 weeks in the laboratory and at least 6 weeks in the field.
PEST MANAGEMENT SCIENCE
(2021)
Review
Parasitology
Mario A. J. Golding, Simmoy A. A. Noble, Nadia K. Khouri, Rhaheem N. A. Layne-Yarde, Inshan Ali, Simone L. Sandiford
Summary: Dengue remains a significant public health concern in Latin America and the Caribbean, with both horizontal and vertical transmission contributing to its spread. While there have been reports of vertical transmission of the dengue virus, its epidemiological significance is still debated.
PARASITES & VECTORS
(2023)
Article
Medicine, General & Internal
Triwibowo Ambar Garjito, Lulus Susanti, Mujiyono Mujiyono, Mega Tyas Prihatin, Dwi Susilo, Sidiq Setyo Nugroho, Mujiyanto Mujiyanto, Raden Ajeng Wigati, Tri Baskoro Tunggul Satoto, Sylvie Manguin, Laurent Gavotte, Roger Frutos
Summary: There are various methods to collect and assess the abundance of dengue vector mosquitoes, but the lack of long-term sampling methods may result in variability and lack of statistical significance in the results. There is no correlation between the collection methods and the presence of dengue virus in mosquitoes or the incidence of dengue, and the efficacy of a given method is inconsistent across different locations.
FRONTIERS IN MEDICINE
(2021)
Article
Multidisciplinary Sciences
Sivaneswari Selvarajoo, Jonathan Wee Kent Liew, Tock H. Chua, Wing Tan, Rafdzah Ahmad Zaki, Romano Ngui, Wan Yusoff Wan Sulaiman, Poo Soon Ong, Indra Vythilingam
Summary: This study found that using a combination of gravid oviposition sticky (GOS) traps and dengue non-structural 1 (NS1) antigen testing can effectively reduce the occurrence of dengue cases by early surveillance of Aedes mosquitoes. The study also showed that this surveillance method significantly improved participants' knowledge, attitude, and practice towards dengue control.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Chun -Ting Yeh, Shih-Che Weng, Po-Nien Tsao, Shin -Hong Shiao
Summary: Binding immunoglobulin protein (BiP) plays a crucial role in both dengue virus replication and mosquito reproduction. Silencing BiP expression inhibits viral replication and reduces mosquito fertility and fecundity.
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2023)
Article
Parasitology
Maria C. Carrasquilla, Mario I. Ortiz, Cielo Leon, Silvia Rondon, Manisha A. Kulkarni, Benoit Talbot, Beate Sander, Heriberto Vasquez, Juan M. Cordovez, Camila Gonzalez
Summary: A study conducted in Ibague, Colombia found that Aedes aegypti and Aedes albopictus mosquitoes are vectors for dengue, Zika, and chikungunya viruses, with dengue and chikungunya circulating in the area but Zika virus remaining undetected. The research results showed that mosquitoes were mainly found in low socioeconomic areas and indoors, with a higher number of female mosquitoes that have fed on human blood, indicating a high risk of arbovirus transmission in Ibague.
PARASITES & VECTORS
(2021)
Article
Virology
Yue Chen, Ronghua Chen, Jianrong Gao, Chunyuan Li, Jun Liu, Zhijian Zhou, Ruiwen Ren
Summary: The study reveals that in the Pearl River Delta, Aedes albopictus can transmit dengue virus during the winter months, sustaining local dengue outbreaks through vertical transmission.
Article
Immunology
Triwibowo Ambar Garjito, Widiarti Widiarti, Muhammad Choirul Hidajat, Sri Wahyuni Handayani, Mujiyono Mujiyono, Mega Tyas Prihatin, Rosichon Ubaidillah, Mohammad Sudomo, Tri Baskoro Tunggul Satoto, Sylvie Manguin, Laurent Gavotte, Roger Frutos
Summary: Genetic diversity differs between Ae. aegypti and Aedes albopictus populations in Indonesia, with a high degree of homogeneity observed across regions, potentially indicating population replacement.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Review
Virology
Khanzadi Nazneen Manzoor, Farakh Javed, Muhammad Ejaz, Mubashar Ali, Neelam Mujaddadi, Abid Ali Khan, Aamer Ali Khattak, Assad Zaib, Ibrar Ahmad, Waqar Khalid Saeed, Sobia Manzoor
Summary: Chickengunya virus (CHIKV) is a newly emerged global virus transmitted mainly by mosquito bites, with a genome containing 11,900 nucleotides. Infections lead to symptoms such as high fever, joint pain, and rashes, and there is currently no specific vaccine or treatment available for CHIKV.
REVIEWS IN MEDICAL VIROLOGY
(2022)
Article
Public, Environmental & Occupational Health
Luisa Barzon, Federico Gobbi, Gioia Capelli, Fabrizio Montarsi, Simone Martini, Silvia Riccetti, Alessandro Sinigaglia, Monia Pacenti, Giacomina Pavan, Mario Rassu, Maria Teresa Padovan, Vinicio Manfrin, Francesca Zanella, Francesca Russo, Felice Foglia, Luca Lazzarini
Summary: In August 2020, in Italy, an autochthonous dengue outbreak was identified for the first time in the context of the COVID-19 pandemic. Following the index case, epidemiological investigation, vector control, and safety measures were immediately activated, leading to the identification of multiple autochthonous cases.
JOURNAL OF TRAVEL MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Xiaocong Li, Binbin Jin, Yunqiao Dong, Xiaoguang Chen, Zhijian Tu, Jinbao Gu
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2019)
Article
Genetics & Heredity
Ye Xu, Yunqiao Dong, Yazhou Xu, Zetian Lai, Binbin Jin, Yanqiang Hao, Yonghui Gao, Yan Sun, Xiao-guang Chen, Jinbao Gu
FRONTIERS IN GENETICS
(2019)
Article
Biochemistry & Molecular Biology
Peiwen Liu, Binbin Jin, Xiaocong Li, Yijie Zhao, Jinbao Gu, James K. Biedler, Zhijian Jake Tu, Xiao-Guang Chen
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2020)
Article
Entomology
Binbin Jin, Yijie Zhao, Yunqiao Dong, Peiwen Liu, Yan Sun, Xiaocong Li, Xin Zhang, Xiao-Guang Chen, Jinbao Gu
Summary: Sexual development in insects is regulated by a complex cascade of sex determination, with diverse signals and a relatively conserved central doublesex (dsx) gene. In Aedes albopictus, the dsx gene produces one male and three female-specific isoforms, with the presence of Nix influencing the direction of sex differentiation.
Article
Agronomy
Binbin Jin, Yijie Zhao, Peiwen Liu, Yan Sun, Xiaocong Li, Xin Zhang, Xiao-Guang Chen, Jinbao Gu
Summary: This study characterized the sex-specific splicing forms of the Ae. albopictus dsx gene and identified direct target genes of DSX in adult females. The results suggest that direct regulation of Aalbdsx on VgR is essential for ovarian development in Ae. albopictus, providing insight into the evolutionarily conserved role of dsx in sexual differentiation and potential molecular targets for vector control.
PEST MANAGEMENT SCIENCE
(2021)
Article
Genetics & Heredity
Yijie Zhao, Binbin Jin, Peiwen Liu, Xiaolin Xiao, Lijun Cai, Zhensheng Xie, Ling Kong, Tong Liu, Wenqiang Yang, Yang Wu, Jinbao Gu, Zhijian Tu, Anthony A. James, Xiao-Guang Chen
Summary: This study found that AalNix is the primary signal for male sex determination in Aedes albopictus and can convert females into phenotypically masculinized pseudo-males while still retaining their fertility and flight capability.