Absorption, distribution, metabolism and excretion of an isocitrate dehydrogenase-2 inhibitor enasidenib in rats and humans
出版年份 2018 全文链接
标题
Absorption, distribution, metabolism and excretion of an isocitrate dehydrogenase-2 inhibitor enasidenib in rats and humans
作者
关键词
-
出版物
XENOBIOTICA
Volume -, Issue -, Pages 1-11
出版商
Informa UK Limited
发表日期
2018-01-11
DOI
10.1080/00498254.2018.1425511
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Molecular Pathways: IDH2 Mutations--Co-opting Cellular Metabolism for Malignant Transformation
- (2015) E. M. Stein CLINICAL CANCER RESEARCH
- Assessment of the absorption, metabolism and excretion of [14C]pasireotide in healthy volunteers using accelerator mass spectrometry
- (2013) T.-H. Lin et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation
- (2013) F. Wang et al. SCIENCE
- The Origin and Evolution of Mutations in Acute Myeloid Leukemia
- (2012) John S. Welch et al. CELL
- A Single Dose Mass Balance Study of the Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Humans Using Accelerator Mass Spectrometry
- (2011) R. A. Graham et al. DRUG METABOLISM AND DISPOSITION
- The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
- (2010) Patrick S. Ward et al. CANCER CELL
- IDH1andIDH2Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study
- (2010) Guido Marcucci et al. JOURNAL OF CLINICAL ONCOLOGY
- Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
- (2010) Stefan Gross et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IDH1 and IDH2 mutation analysis in chronic- and blast-phase myeloproliferative neoplasms
- (2010) A Pardanani et al. LEUKEMIA
- Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms
- (2010) O Kosmider et al. LEUKEMIA
- Practical experience of using human microdosing with AMS analysis to obtain early human drug metabolism and PK data
- (2010) R Colin Garner Bioanalysis
- Addressing metabolite safety during first-in-man studies using14C-labeled drug and accelerator mass spectrometry
- (2010) Graham Lappin et al. Bioanalysis
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
- IDH1andIDH2Mutations in Gliomas
- (2009) Hai Yan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Biomedical accelerator mass spectrometry: recent applications in metabolism and pharmacokinetics
- (2008) Graham Lappin et al. Expert Opinion on Drug Metabolism & Toxicology
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- (2008) D. W. Parsons et al. SCIENCE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started