Article
Chemistry, Applied
Yucun Liu, Ning Li, Yongling Zhang, Yuan Wang
Summary: A sophisticated fluorescent chemosensor, NPDI, was designed and synthesized through a one-step condensation reaction. It exhibited fluorescence enhancement response toward Al3+, beginc accompanied by significant emission color change without interference from other metal ions. The binding stoichiometry and mechanism were confirmed using various techniques.
Article
Chemistry, Analytical
Paulina Takacsova, Marie Kudlickova Peskova, Pavel Svec, Zbynek Heger, Vladimir Pekarik
Summary: Single-benzene fluorophores, the smallest and brightest fluorochromes known, have not been extensively studied for the design of high-performance fluorescent sensors of catalytic or enzymatic activities. In this study, new fluorescent probes based on the Tsuji-Trost reaction were developed for selective detection of palladium and other transition metals in an aqueous/organic mixed solvent with high sensitivity. The flexibility in synthesis allows for easy tuning of the emitted fluorescence color, and the yellow emission variant shows promising applicability in sensitive detection of palladium in cell-free and living cell conditions.
Article
Chemistry, Analytical
Anusha A. Mahishi, Sachin M. Shet, Padmaja V. Mane, Jingxian Yu, A. Ve. Sowriraajan, Madhuprasad Kigga, Mahesh P. Bhat, Kyeong-Hwan Lee, Mahaveer D. Kurkuri
Summary: A Schiff base receptor with an active -NH group was synthesized for the colorimetric detection of inorganic fluoride (F-) ions in an aqueous medium. The receptor showed enhanced sensitivity for F- ions due to the presence of electron-withdrawing -NO2 groups, resulting in a remarkable color change. Characterization techniques confirmed the structural integrity of the synthesized receptors and a binding mechanism involving deprotonation of the -NH group and formation of -HF2 was proposed.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Amany R. Salem, Abeer M. El-Naggar, Ekram H. Mohamed, Mohammed A. Amin, Mohamed S. Attia
Summary: A newly developed spectrofluorometric method utilizing a microwave-irradiated optical cyanopyridine derived sensor effectively quenched fluorescence intensity in the presence of UO22+ ions in DMSO at specific wavelengths. The quenching effect was found to be proportional to the concentration of UO22+ ion, providing detection and quantification limits for the sensor.
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
(2022)
Article
Chemistry, Applied
Alen Sam Thomas, Apurba Pramanik, Sara Amer, Vered Marks, Mindy Levine
Summary: This study reports the design, synthesis, and application of a highly solvatochromic coumarin derivative (compound 1) for water detection. The solvatochromism of compound 1 is attributed to the presence of an electron-withdrawing aldehyde substituent and an electron-donating diethylamino group. Compound 1 shows significant fluorescence responsiveness to polar protic solvents, especially with a pronounced decrease in fluorescence upon the addition of small amounts of water. This water-based responsiveness is utilized in the development of a fluorescent water sensor with rapid, sensitive, and irreversible fluorescence quenching to both liquid water and water vapor.
Review
Environmental Sciences
Qiaohui Zhong, Jianying Qi, Juan Liu, Jin Wang, Ke Lin, Qi'en Ouyang, Xian Zhang, Xudong Wei, Tangfu Xiao, Ali El-Naggar, Joerg Rinklebe
Summary: This review summarizes the sources, characteristics and tracing methods of thallium pollution in the environment, and proposes further research directions and possible limitations for the application of thallium isotopes in environmental contamination.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Biochemical Research Methods
Sorour Ramezanpour, Hamed Barzinmehr, Pezhman Shiri, Chris Meier, Seyed Abdulmajid Ayatollahi, Mehrdad Mehrazar
Summary: Two novel fluorescent peptide-based chemosensors, A and B, show excellent selectivity and sensitivity towards Al3+ ions with detection limits of 155 nM and 195 nM respectively. They form a 1:1 coordination complex with Al3+ and produce turn-on responses through an intramolecular charge transfer mechanism.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Ananta Hazra, Partha Roy
Summary: A rhodamine-based compound, L1, has been developed for colorimetric and fluorometric sensing of Group 13 cations in aqueous solution, showing high sensitivity towards Al3+, Ga3+, In3+ and Tl3+ ions with significant color change and fluorescence enhancement.
ANALYTICA CHIMICA ACTA
(2022)
Review
Chemistry, Applied
Danish Khan, Shaily
Summary: This article summarizes the application of coumarin probes in the detection of various species. It emphasizes the mechanisms involved and highlights the recent developments in the design of such probes. Additionally, it draws attention to the application protocol and shortcomings of reported coumarin-based fluorescent probes, providing insights for future progress in this field. It is believed that this review can serve as a reference guide for novices and contribute to advancements in biological and chemical research.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Applied
G. Prabakaran, R. Vickram, K. Velmurugan, C. Immanuel David, S. Prince Makarios Paul, Raju Suresh Kumar, Abdulrahman I. Almansour, Karthikeyan Perumal, A. Abiram, J. Prabhu, R. Nandhakumar
Summary: A dimeric quinoline-based Schiff base (DQS) was developed as a probe for the specific detection of Pb(2+) ions using fluorimetry. The binding of DQS with Pb2+ resulted in enhanced fluorescence intensity with a blue shift, attributed to the restriction of C-N rotation, C= N isomerization, and photoinduced electron transfer (PET) mechanisms. Moreover, intramolecular charge transfer (ICT) from an electron-donating morpholine group to a phenylene diamine acceptor linked to the quinoline bridge was responsible for the blue-shifted fluorescence enhancement in the DQS-Pb2+ complex.
Article
Chemistry, Analytical
Chenming Chan, Jia Li, Zhaoli Xue, Fengxian Qiu
Summary: The sensor based on phenolic substituted dicyanoisophorone derivative can detect cyanide ions through quenching fluorescence, providing a convenient method for detection in natural water samples and biological systems.
MICROCHEMICAL JOURNAL
(2021)
Review
Chemistry, Applied
Farid Ahmed, Hai Xiong
Summary: This review summarizes the latest developments in chemosensors based on click generated triazoles for a range of metal cations, anions, and neutral analytes, highlighting the need for continuous research accumulation in this rapidly growing field to meet demand.
Article
Spectroscopy
Bin Wang, Weiling Xu, Kaifeng Gan, Ke Xu, Qiaojie Chen, Wei Wei, Wei Wu
Summary: This article reports a fluorescent colorimetric chemosensor CS1 based on the mechanism of internal charge transfer (ICT) for sensitive and reliable detection of Cu2+. It shows a visually dramatic color change and provides a quantification method for Cu2+ determination. The sensor has a low detection limit and reversible sensing detection for Cu2+ ions.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Peraya Hiranmartsuwan, Sirilak Wangngae, Jukkrit Nootem, Anyanee Kamkaew, Rathawat Daengngern, Worawat Wattanathana, Kantapat Chansaenpak
Summary: In this study, two pyridylhydrazone-tethered BODIPY compounds were synthesized and characterized. These compounds have the ability to selectively detect hypochlorous acid (HOCl) through a fluorescence turn-on mechanism. In cell imaging experiments, they showed excellent biocompatibility and visualization of endogenous HOCl in living cells.
Article
Chemistry, Analytical
Olga D. Hendrickson, Liliya I. Mukhametova, Elena A. Zvereva, Anatoly V. Zherdev, Sergei A. Eremin
Summary: A homogeneous fluorescence polarization immunoassay (FPIA) was developed for the detection of hazardous aquatic toxin okadaic acid (OA) in environmental waters. The FPIA showed a limit of OA detection of 0.08 ng/mL (0.1 nM) and a working range of 0.4-72.5 ng/mL (0.5-90 nM). The method was successfully applied for the determination of OA in river water and seawater samples without the need for sample preparation.
Article
Environmental Sciences
Matilde Vieira Sanches, Rosa Freitas, Matteo Oliva, Angelica Mero, Lucia De Marchi, Alessia Cuccaro, Giorgia Fumagalli, Andrea Mezzetta, Greta Colombo Dugoni, Monica Ferro, Andrea Mele, Lorenzo Guazzelli, Carlo Pretti
Summary: The traditional use of organic solvents is being rethought due to their high volatility, toxicity, and interaction with biological membranes. Green Chemistry focuses on developing sustainable and cost-effective solvent alternatives such as Ionic Liquids (ILs), bio-based solvents, and natural deep eutectic solvents (NADESs). This study screened 15 NADESs for ecotoxicity using marine and freshwater bioassays, finding no toxicity to invertebrates but potential biostimulation effects on algae. However, the intentional or accidental release of NADESs into aquatic systems may pose risks to ecosystem functioning.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Chemistry, Multidisciplinary
J. Afonso, A. Mezzetta, I. M. Marrucho, L. Guazzelli
Summary: The establishment of Deep Eutectic Solvents (DESs) as a new class of green solvents was initially based on naive comparisons with Ionic Liquids (ILs), but further research has emphasized the need for a thermodynamic definition and differentiation from other solvents. This perspective review presents experimental and computational data to dispel myths about DESs and make fair comparisons with other solvents, such as ILs, eutectic solvents (ESs), and volatile organic compounds (VOCs). The unique potential of DESs in biopolymer dissolution and treatment is highlighted, along with considerations for recycling and techno-economic aspects.
Article
Biochemistry & Molecular Biology
Brunella Grassiri, Andrea Mezzetta, Giuseppantionio Maisetta, Chiara Migone, Angela Fabiano, Semih Esin, Lorenzo Guazzelli, Ylenia Zambito, Giovanna Batoni, Anna Maria Piras
Summary: The study evaluated the use of ionic liquids (ILs) as functional excipients for solubilizing and stabilizing diacerein (DIA) in eye drop formulations and prolonging its ocular residence time. Two ILs based on natural zwitterionic compounds were investigated: L-carnitine C6 alkyl ester bromide (Carn6) and betaine C6 alkyl ester bromide (Bet6). The ILs demonstrated solubilizing, stabilizing, mucoadhesive, and antimicrobial properties, with potential for future use in ophthalmic applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Physics, Applied
Nicola Melchioni, Giacomo Trupiano, Giorgio Tofani, Riccardo Bertini, Andrea Mezzetta, Federica Bianco, Lorenzo Guazzelli, Fabio Beltram, Christian Silvio Pomelli, Stefano Roddaro, Alessandro Tredicucci, Federico Paolucci
Summary: Controlling charge density in low-dimensional materials using an electrostatic potential is a powerful tool to explore and manipulate their electronic and optical properties. Ionic liquid (IL) gating, which only requires a metallic electrode in contact with IL, provides an alternative method with excellent gating properties. However, many ILs are not suitable for optical experiments in the mid-IR region due to low optical transparency and degradation. In this study, we present two electrolytes based on bromide ILs dissolved in PMMA, which can achieve high charge densities and exhibit optical transparency, making them promising candidates for electronic and mid-IR optoelectronic devices.
APPLIED PHYSICS LETTERS
(2023)
Article
Chemistry, Physical
Angelica Mero, Spyridon Koutsoumpos, Panagiotis Giannios, Ilias Stavrakas, Konstantinos Moutzouris, Andrea Mezzetta, Lorenzo Guazzelli
Summary: Within the field of green chemistry, deep eutectic solvents (DESs) are becoming increasingly important due to their unique physicochemical properties. In this study, a comparative analysis was conducted on six different DESs to investigate the effects of various parameters such as the nature of the hydrogen bond acceptor (HBA) and donor (HBD) and their molar ratio on properties including density, viscosity, refractive index, thermal stability, and thermal behavior. The results showed that DESs based on ethylene glycol (EG) exhibited the lowest density and viscosity, while those based on glycerol (Gly) had the highest values. Switching from choline chloride (ChCl) to betaine (Bet) as the HBA resulted in higher viscosity and density. Increasing the amount of HBD in the DESs led to lower viscosity, increased density for Gly-based DESs, and decreased density for EG and levulinic acid (LevA)-based DESs. The refractive index decreased with increasing HBD portion, but using ChCl instead of Bet as the HBA resulted in a higher refractive index. The thermal stability of the DESs was strongly influenced by the HBD used, with EG-based DESs being less stable than LevA-based ones and Gly-based DESs exhibiting the highest stability. Additionally, three characteristic mass loss events were observed in all DESs, attributed to the evaporation/degradation of the HBD, HBD-HBA interaction, and the HBA. Finally, differential scanning calorimetry (DSC) analyses showed that all DESs can be used as solvents due to their liquid state at room temperature and their ability to maintain liquid state over a wide temperature range.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Biochemistry & Molecular Biology
Sharon Monaci, Daniela Minudri, Lorenzo Guazzelli, Andrea Mezzetta, David Mecerreyes, Maria Forsyth, Anthony Somers
Summary: Corrosion is a major problem that affects structures and buildings, leading to premature failure and economic loss. Biobased lignin and ionic liquids have shown potential as corrosion inhibitors. This study investigated the inhibitory properties of new biobased lignin ionic liquids and found that one of them exhibited promising performance.
Review
Environmental Sciences
Matilde Vieira Sanches, Rosa Freitas, Matteo Oliva, Alessia Cuccaro, Gianfranca Monni, Andrea Mezzetta, Lorenzo Guazzelli, Carlo Pretti
Summary: The potential release of ionic liquids into aquatic systems has led to concerns about their ecotoxicological effects on aquatic microorganisms and invertebrate species. This review examines 103 studies on ionic liquids and their toxicity to aquatic organisms, focusing on the factors influencing their toxicity. Freshwater species were studied more frequently than marine species, with algal species being the most commonly assessed. The combination of imidazolium cations with long alkyl-chain anions was found to be the most toxic.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Inorganic & Nuclear
Luca Guglielmero, Andrea Mezzetta, Felicia D'Andrea, Lorenzo Guazzelli, Christian Silvio Pomelli
Summary: A panel of novel vanadium(iv)-betaine complexes has been synthesized and their stability under different temperature and acidity conditions has been studied. The results showed that the betaine ligands significantly affect the stability of aqueous vanadium(V) solutions. The species formed in the betaine rich vanadium(V) solutions have been spectroscopically identified and confirmed through computational techniques. Furthermore, the vanadium-betaine based electrolyte solutions have been tested in lab-scale redox flow battery setup.
DALTON TRANSACTIONS
(2023)
