Article
Agriculture, Dairy & Animal Science
Maria A. Pereira, Rute Santos, Carmen Nobrega, Cristina Mega, Rita Cruz, Fernando Esteves, Carla Santos, Catarina Coelho, Joao R. Mesquita, Helena Vala, Gabriela Santos-Gomes
Summary: Canine Leishmaniosis is a chronic and potentially fatal disease caused by Leishmania infantum. Financial restraints of dog owners in Portugal negatively influence veterinary follow-up and relapse recognition. Most veterinary practitioners detect relapses through the reappearance or worsening of clinical signs.
Article
Veterinary Sciences
Alice Vismarra, Laura Helen Kramer, Anna Moschi, Lavinia Ciuca, Marco Genchi
Summary: The study surveyed Italian practitioners on managing CanL and comparing their practices to guidelines from ESCCAP, Leishvet, and C.L.W.G. Results showed good awareness among practitioners, with 16% carrying out year-long prevention despite transmission being seasonal in Italy. This high level of awareness presents an opportunity for updating guidelines to include new information for correct management of CanL.
PREVENTIVE VETERINARY MEDICINE
(2021)
Article
Parasitology
Marta Monteiro, Sara Prata, Luis Cardoso, Isabel Pereira da Fonseca, Rodolfo Oliveira Leal
Summary: This survey investigated the current trends in the clinical management of CanL among veterinary practitioners in Portugal, showing that most veterinarians follow international guidelines, with different therapeutic protocols preferred for different stages of CanL. The study provides insights into practical approaches to the treatment of CanL in Portugal.
PARASITES & VECTORS
(2021)
Article
Microbiology
Isaia Symeonidou, Georgios Sioutas, Athanasios I. Gelasakis, Constantina N. Tsokana, Elias Papadopoulos
Summary: Leishmaniosis caused by Leishmania infantum is a major veterinary concern in Greece. The country has favorable environmental conditions for the spread of this infection. With Greece being a popular tourist destination, the constant travel of pets raises concerns about the dissemination of infection to non-endemic areas. Surveillance and identification of high-risk areas are necessary to establish preventative protocols for travelling animals.
Article
Agriculture, Dairy & Animal Science
Maria Paz Peris, Paula Ortega-Hernandez, Mariano Morales, Juan Antonio Castillo, Bernardino Moreno
Summary: This study presents three cases of dogs experimentally infected with Leishmania infantum that showed atypical lesions of canine leishmaniosis. Microscopic and parasitological studies should be performed on atypical lesions observed in Leishmania-infected and non-infected dogs, especially in endemic regions. Leishmaniosis should be considered when atypical nodular lesions are observed in dogs from non-endemic regions with a history of travel to endemic regions.
Article
Agriculture, Dairy & Animal Science
Victoriano Corpas-Lopez, Victoriano Diaz-Saez, Francisco Morillas-Marquez, Francisco Franco-Montalban, Monica Diaz-Gavilan, Julian Lopez-Viota, Margarita Lopez-Viota, Jose Antonio Gomez-Vidal, Joaquina Martin-Sanchez
Summary: A new drug, MTC-305, has been found to be effective and non-toxic in treating canine leishmaniosis, a challenging disease in veterinary medicine. This study suggests that MTC-305 and other O-alkyl hydroxamates could be promising in the fight against this neglected disease.
Article
Veterinary Sciences
Maria Alfonsa Cavalera, Floriana Gernone, Annamaria Uva, Rossella Donghia, Grazia Carelli, Roberta Iatta, Andrea Zatelli
Summary: This study aims to evaluate the erythrocyte sedimentation rate (ESR) in Leishmania infantum-seropositive dogs and its correlation with the clinical form of Canine leishmaniosis (CanL) and acute phase proteins (APPs). The results showed that dogs with CanL active form have significantly higher ESR levels compared to exposed and healthy dogs. ESR evaluation can be considered as a simple and useful inflammatory biomarker for the diagnosis of CanL active form.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Immunology
Picabo Binette, Mahelat Tesfamariam, Diane Cockrell, Robert A. Heinzen, Crystal Richards, Carl Shaia, Carrie Mae Long
Summary: This study investigates the immunologic mechanisms of delayed-type hypersensitivity (DTH) response to Q fever vaccine. Using a murine model, it is found that female mice display a more robust early-phase DTH response compared to male mice and other strains. The study also suggests that sex is a primary factor influencing the magnitude and composition of the ensuing response.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Agriculture, Dairy & Animal Science
Erin A. Beasley, Danielle Pessoa-Pereira, Breanna M. Scorza, Christine A. Petersen
Summary: Canine leishmaniosis (CanL) is a severe, visceralizing disease caused by Leishmania infantum, transmitted by phlebotomine sand flies. Co-infections with other tick-borne diseases are common in regions where CanL is endemic. These co-infections can impact immune responses and disease progression, affecting diagnosis, treatment, and prognosis of CanL. Further research is needed to explore the immunomodulation and clinical impact of co-infections in dogs with CanL.
Article
Infectious Diseases
Graziella Borges Alves, Talita Carolina Braganca de Oliveira, Lilian Colebrusco Rodas, Daniela Bernadete Rozza, Alex Akira Nakamura, Elis Domingos Ferrari, Debora Regina Romualdo da Silva, Gisele Moraes dos Santos, Eliana Bravo Calemes, Keuryn Alessandra Mira Luz Requena, Walter Bertequini Nagata, Thais Rabelo Santos-Doni, Katia Denise Saraiva Bresciani
Summary: This study assessed the effectiveness of a polymer matrix collar containing 10% imidacloprid and 4.5% flumethrin for the prevention of canine leishmaniosis in Brazil. The results showed that the collar was 89.2% effective in protecting against L. infantum infection and was safe and efficient for use in highly prone endemic regions.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Agriculture, Dairy & Animal Science
Michela Pugliese, Alessandra Sfacteria, Gaetano Oliva, Annastella Falcone, Manuela Gizzarelli, Annamaria Passantino
Summary: This study investigated the role of oxidative stress parameters (ROMs, OXY, SHp), the Oxidative Stress index (OSi), and High Mobility Group Box-1 protein (HMGB-1) in canine leishmaniosis. Results suggest a potential role of oxidative stress in the pathogenesis of CanL. Further studies are needed to explore the direct correlation between inflammation parameters and the different stages of CanL, as well as the role of ROMs in the onset of anemia.
Editorial Material
Parasitology
Guadalupe Miro, Juliana Sarquis, Luis Cardoso, Patrick Bourdeau, Laia Solano-Gallego, Gaetano Oliva, Maria Grazia Pennisi, Christine Petersen, Lluis Ferrer, Gad Baneth
Summary: The organizers of the 1st congress on animal leishmaniosis (ALIVE) in Malaga, Spain, discuss the recent advances in the field presented during the meeting.
TRENDS IN PARASITOLOGY
(2022)
Article
Microbiology
Sergi Segarra
Summary: Leishmaniasis is a growing zoonotic disease exacerbated by climate change, with dogs as the main reservoir. Standard treatment for canine leishmaniosis is effective but not always sufficient, highlighting the potential role of dietary nucleotides in modulating the immune response for better disease management.
Article
Infectious Diseases
Ali Bouattour, Amine Amri, Jaber Amine Belkhiria, Adel Rhim, Ons Fezaa, Jean-Charles Gantier, Youmna M'ghirbi
Summary: Leishmania infantum, an intracellular protozoan responsible for zoonotic canine leishmaniosis, has a high prevalence in dogs in Tunisia, varying by bioclimatic area and age group. The expansion of infection in dog population may be attributed to ecological, agronomic, social, and climatic factors.
PLOS NEGLECTED TROPICAL DISEASES
(2021)
Article
Microbiology
Manuela Gizzarelli, Valentina Manzillo, Antonio Inglese, Serena Montagnaro, Gaetano Oliva
Summary: The study evaluated the efficacy of the MIL-AL protocol for the long-term treatment of canine leishmaniosis. The findings showed that MIL-AL was effective in improving clinical symptoms and clinicopathological indicators in dogs with the disease, with minimal side effects.
Article
Parasitology
Silvia Belinchon-Lorenzo, Juan Carlos Parejo, Virginia Iniesta, Javier Fernandez-Cotrina, Ruben Munoz-Madrid, Isabel Monroy, Victoria Baz, Adela Gomez-Luque, Francisco Javier Serrano-Aguilera, Jose Luis Barneto, Luis Carlos Gomez-Nieto
VETERINARY PARASITOLOGY
(2016)
Article
Parasitology
Ruben Munoz-Madrid, Silvia Belinchon-Lorenzo, Virginia Iniesta, Javier Fernandez-Cotrina, Juan Carlos Parejo, Francisco Javier Serrano, Isabel Monroy, Victora Baz, Adela Gomez-Luque, Luis Carlos Gomez-Nieto
Article
Parasitology
Virginia Iniesta, Silvia Belinchon-Lorenzo, Manuel Soto, Javier Fernandez-Cotrina, Ruben Munoz-Madrid, Isabel Monroy, Victoria Baz, Adela Gomez-Luque, Juan Carlos Parejo, Carlos Alonso, Luis Carlos Gomez Nieto
Article
Parasitology
Virginia Iniesta, Ines Corraliza, Jesualdo Carcelen, Luis Gomez Gordo, Javier Fernandez-Cotrina, Juan Carlos Parejo, Javier Carrion, Manuel Soto, Carlos Alonso, Carlos Gomez Nieto
PARASITOLOGY RESEARCH
(2008)
Article
Immunology
J. Carcelen, V. Iniesta, J. Fernandez-Cotrina, F. Serrano, J. C. Parejo, I. Corraliza, A. Gallardo-Soler, F. Maranon, M. Soto, C. Alonso, C. Gomez-Nieto
Article
Parasitology
J. Fernandez-Cotrina, V. Iniesta, S. Belinchon-Lorenzo, R. Munoz-Madrid, F. Serrano, J. C. Parejo, L. Gomez-Gordo, M. Soto, C. Alonso, L. C. Gomez-Nieto
VETERINARY PARASITOLOGY
(2013)
Article
Parasitology
Silvia Belinchon-Lorenzo, Virginia Iniesta, Juan Carlos Parejo, Javier Fernandez-Cotrina, Ruben Munoz-Madrid, Manuel Soto, Carlos Alonso, Luis Carlos Gomez Nieto
VETERINARY PARASITOLOGY
(2013)
Article
Immunology
Abel Martinez-Rodrigo, Alicia Mas, Javier Fernandez-Cotrina, Silvia Belinchon-Lorenzo, Jose A. Orden, Pablo Arias, Ricardo de la Fuente, Javier Carrion, Gustavo Dominguez-Bernal
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
(2019)
Article
Veterinary Sciences
Domingo Casamian-Sorrosal, Rafael Barrera-Chacon, Sonja Fonfara, Silvia Belinchon-Lorenzo, Luis Gomez-Gordo, Javier Galapero-Arroyo, Javier Fernandez-Cotrina, Jose Ignacio Cristobal-Verdejo, Francisco Javier Duque
Summary: This study found that MPL levels in dogs with advanced CanL are variable but generally high. A strong association between MPL and cTnI was observed, which suggests further exploration of cTnI as a biomarker in CanL.
Article
Parasitology
Silvia Belinchon-Lorenzo, Ruben Munoz-Madrid, Fernanda Grecco Grano, Virginia Iniesta, Javier Fernandez-Cotrina, Juan Carlos Parejo, Isabel Monroy, Victoria Baz, Adela Gomez-Luque, Jose Luis Barneto, Carolina Grecco Grano Bordini, Gisele Fabrino Machado, Luis Carlos Gomez-Nieto
VETERINARY PARASITOLOGY- REGIONAL STUDIES AND REPORTS
(2019)