Article
Chemistry, Analytical
Mansi Chaturvedi, Monika Patel, Neha Bisht, Maumita Das Mukherjee, Archana Tiwari, D. P. Mondal, Avanish Kumar Srivastava, Neeraj Dwivedi, Chetna Dhand
Summary: Tuberculosis (TB) is a devastating human illness and early diagnosis is crucial. This study proposes an electrochemical biosensor based on a ternary nanocomposite for highly sensitive and selective MTB detection. The sensor showed high sensitivity and stability, and provides a unique strategy for early MTB diagnosis. The electrochemical platform has potential for detecting various infectious pathogens and biomarkers.
Article
Biophysics
Tomas Springer, Zdenek Krejcik, Jiri Homola
Summary: A novel and extremely sensitive label-free optical biosensor-based assay for the detection of miRNAs has been proposed, which enhances specific sensor response while suppressing non-specific binding interference. The assay has been successfully applied to detect miRNAs related to myelodysplastic syndromes in blood plasma, achieving a low detection limit and enabling multiplexed miRNA detection.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Elena Alina Chiticaru, Celina Maria Damian, Luisa Pilan, Mariana Ionita
Summary: This study proposes a simple, label-free, and cost-effective DNA detection platform using screen-printed carbon electrodes modified with reduced graphene oxide and gold nanoparticles. The preparation process and electrochemical properties of the modified electrodes were characterized and confirmed. The introduction of gold nanoparticles onto the electrode surface enhanced surface conductivity and sensitivity in detection.
Article
Chemistry, Physical
Wanxi Li, Boqiong Li, Yali Zhao, Xiaoqin Wei, Fang Guo
Summary: Component regulation and microstructure design are effective strategies to improve microwave absorption performance. A sandwich-like graphene-based absorbent with adjustable Fe3O4 content was synthesized through ultrasonic dispersion, blast drying, and roasting. The sandwich structure formed multiple interfaces, prevented nanoparticle aggregation, and facilitated interface polarization, resulting in enhanced impedance matching and microwave attenuation. The absorbent achieved an effective absorption bandwidth of 5.7 GHz and a minimum reflection loss value of -49.9 dB. Moreover, the synthesis process is simple and suitable for large-scale production and industrial applications. This facile route provides new ideas for designing graphene-based nanocomposites.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Analytical
Shangshang Ma, Qing Zhang, Jun Zhu, Hongwei Shi, Keying Zhang, Yizhong Shen
Summary: By designing a three-dimensional reduced graphene oxide doped with silver nanoparticles, an effective sensing interface was created to detect and evaluate the Hg2+ content in food and human blood samples, providing valuable support for safeguarding food safety and human health.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Materials Science, Multidisciplinary
Xiaohua Jia, Shouwen Yu, Chuande Cheng, Jin Yang, Yong Li, Sizhe Wang, Haojie Song
Summary: Exhaled acetone is a representative biomarker in the non-invasive diagnosis of type I diabetes. A potential acetone sensor, Ag nanoparticles modified Fe3O4/rGO composites, was synthesized, showing good selectivity and high response rate. The Ag/Fe3O4/rGO sensor has a good response and selectivity to acetone, with ultra-high response at 220 degrees C.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Chemistry, Physical
Wencan Hu, Kailong He, Siman Wu, Tianran Chen, Xiaoyuan Yu, Yeru Liang, Mingtao Zheng, Yong Xiao, Hanwu Dong, Yingliang Liu, Hang Hu
Summary: In this study, a novel ordered sandwich-structured nanocomposite consisting of Fe3O4, silicon quantum dots (Si-QDs), and reduced graphene oxide (rGO) is synthesized. Si-QDs play a vital role in guiding the uniform formation and distribution of nano-sized Fe3O4 on rGO nanosheets. The resulting Si-QDs/Fe3O4/rGO composite exhibits high specific capacity, excellent cycling stability, and rate capability. This work provides insights into the effect of Si-QDs on the morphology, structure, and electrochemical performances of the composite.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Chemistry, Analytical
Xiao-Yu Wang, Yi-Ge Feng, Ai-Jun Wang, Li-Ping Mei, Pei-Xin Yuan, Xiliang Luo, Jiu-Ju Feng
Summary: An electrochemical immunosensor was developed for sensitive monitoring of the breast cancer marker HER2, utilizing innovative materials and signal tags to achieve rapid detection with a broad linear range and low detection limit. This sensor shows great potential for screening cancer biomarkers and point-of-care assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Physical
Yuanlin Xie, Yongcai Qiu, Lanlan Tian, Tiefeng Liu, Xintai Su
Summary: A composite material consisting of ultrafine Fe3O4 anchored in reduced graphene oxides is synthesized for application in lithium-ion battery anodes. The hollow Fe3O4/rGO composites show superior specific capacity and cyclic stability compared to solid Fe3O4/rGO composites, attributed to the ultrafine hollow structure shortening Li+ diffusion path and conductive rGO facilitating rapid electron transfer.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Biochemistry & Molecular Biology
Huy Quang Tran, Husna Alam, Abigail Goff, Torben Daeneke, Mrinal Bhave, Aimin Yu
Summary: This work demonstrates the preparation of multifunctional Fe3O4 NPs filled polydopamine hollow rods as a drug carrier platform. The release of the drug fosfomycin from the platform was pH-dependent and triggered by magnetic or laser stimulation. The Fe3O4@PDA HR showed effective elimination of preformed biofilm due to its magnetic and photothermal properties. This study provides an alternative approach to kill pathogenic bacteria using a drug carrier platform.
Article
Multidisciplinary Sciences
Nurul Syazwani Rohizat, Atiena Husna Abdullah Ripain, Chin Seong Lim, Chee Leong Tan, Rozalina Zakaria
Summary: The study demonstrates the significant enhancement of the photoresponse of photodetectors by combining hybrid plasmonic nanoparticles and graphene; high-performance photodetectors were successfully fabricated by integrating metallic nanoparticles with reduced graphene oxide; Au-rGO showed the highest responsivity and specific detectivity at 680nm wavelength, while Ag-rGO achieved the best performance at 785nm wavelength.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Analytical
Shuzhou Guo, Yaping Lin, Ziqi Lian, Tao Zeng, Liangliang Wang, Rongkai Ye, Benlin Hong, Qianwei Liang, Qianqing Wu, Jianqiang Hu, Aiqing Li
Summary: In this study, a label-free ultrasensitive biosensor was successfully developed for instant detection of miRNA-21, which has wide applications in early diagnosis of diseases like cancer and acute kidney injury. The biosensor showed high sensitivity, wide linear range, low limit of detection, and demonstrated specificity, stability, and reproducibility in detecting miRNA-21 in real urine samples.
MICROCHEMICAL JOURNAL
(2023)
Article
Materials Science, Composites
Jigang Feng, Babak Safaei, Zhaoye Qin, Fulei Chu
Summary: This study designs and prepares nature-inspired sandwich composites for vibration suppression, which exhibit improved damping properties and surface friction force compared to conventional blended composites. Dynamic mechanical analysis and vibration test results confirm the superior damping properties of sandwich composites. Polydopamine modification of reduced graphene oxide (rGO) enhances the damping capability, providing an effective strategy for vibration energy dissipation and damping enhancement.
COMPOSITES SCIENCE AND TECHNOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Briliant Adhi Prabowo, Agnes Purwidyantri, Bei Liu, Hsin-Chih Lai, Kou-Chen Liu
Summary: The study investigated the impact of different gold nanoparticle structures on plasmonic enhancement for DNA detection on a few-layer graphene surface plasmon resonance sensor. The use of gold nano-urchins significantly reinforced the overall DNA hybridization signal, reaching the femtomolar range limit of detection. The integrated approach of the graphene-based SPR sensor and GNu-assisted DNA detection provided a proof-of-concept for tuberculosis disease screening in low-resource settings.
Article
Chemistry, Analytical
Kimia Kermanshahian, Abbas Yadegar, Hamid Moghimi, Hedayatollah Ghourchian
Summary: This study confirms the ability of Fe3O4@Au nanoparticles in iodide oxidation and utilizes the synergy between these nanoparticles and molybdate ions to enhance the etching rate, resulting in a rapid, cost-effective, and ultrasensitive genosensor for H. pylori detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
