Review
Medicine, General & Internal
Alba Nicolas-Boluda, Anne Oppenheimer, Jerome Bouaziz, Arnaud Fauconnier
Summary: Patient Reported Outcome Measures (PROM) allow capturing patients' perspectives on their condition in the context of endometriosis care. Despite their extensive use in research and clinical trials, PROMs are rarely used in clinical practice. The development of digital tools can help facilitate the integration of PROMs into routine endometriosis care, improving patient-centered communication and quality of life.
JOURNAL OF CLINICAL MEDICINE
(2021)
Editorial Material
Dermatology
C. C. Zouboulis, P. V. Chernyshov
Summary: The study by R. Sommer et al. published in the Journal of the European Academy of Dermatology and Venereology in 2021 focused on a specific topic in the field of dermatology.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2021)
Review
Psychiatry
Danilo Carrozzino, Chiara Patierno, Jenny Guidi, Carmen Berrocal Montiel, Jianxin Cao, Mary E. Charlson, Kaj Sparle Christensen, John Concato, Carlos De las Cuevas, Jose De Leon, Ajandek Eory, Marcelo Pio Fleck, Toshi A. Furukawa, Ralph I. Horwitz, Andrew A. Nierenberg, Chiara Rafanelli, Hongxing Wang, Thomas N. Wise, Nicoletta Sonino, Giovanni A. Fava
Summary: PROMs are self-rated scales and indices developed to improve the detection of patients' subjective experience. The psychometric model's limitations highlight the need for a more suitable framework, such as clinimetrics. Clinimetric and psychometric approaches differ in terms of characteristics related to reliability, sensitivity, validity, and clinical utility of instruments.
PSYCHOTHERAPY AND PSYCHOSOMATICS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Ilham Mounssif, Valentina Bentivogli, Alexandra Rendon, Davide B. Gissi, Francesco Maiani, Claudio Mazzotti, Monica Mele, Matteo Sangiorgi, Giovanni Zucchelli, Martina Stefanini
Summary: The present study aimed to investigate the impact of different periodontal surgical treatments on the quality of life and postoperative morbidity. The results revealed that periodontal surgical procedures have a low impact on patients' quality of life and a limited duration of postoperative discomfort as well as the incidence of complications.
CLINICAL ORAL INVESTIGATIONS
(2023)
Review
Health Care Sciences & Services
Priscilla Jia Ling Wee, Yu Heng Kwan, Dionne Hui Fang Loh, Jie Kie Phang, Troy H. Puar, Truls Ostbye, Julian Thumboo, Sungwon Yoon, Lian Leng Low
Summary: This study systematically reviewed 238 unique PROMs for patients with type 2 diabetes, categorized them based on their measurement properties, and may assist clinicians and researchers in selecting appropriate high-quality PROMs for clinical practice and research.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Review
Medicine, General & Internal
Zachary Blood, Anh Tran, Lauren Caleo, Robyn Saw, Mbathio Dieng, Mark Shackleton, H. Peter Soyer, Chris Arnold, Graham J. Mann, Rachael L. Morton
Summary: This systematic review identified PROMs and PREMs used in clinical quality registries for cutaneous melanoma patients, showing that they can enhance care transparency, quality assessment, and research, yet challenges such as resource burden and collection bias may limit their generalizability.
Article
Orthopedics
Zachary T. Sharfman, Nathan Safran, Eyal Amar, Kunal Varshneya, Marc R. Safran, Ehud Rath
Summary: This study found that hip-specific PROM scores in asymptomatic individuals decrease with age. Comparing a patient's outcome scores with age-normalized scores can help establish an accurate reference frame for interpreting outcomes.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2022)
Editorial Material
Oncology
Derek K. Smith
Summary: This paper presents the lesser-understood implications of using patient-reported outcome measures in clinical research. It demonstrates that the assumptions of common mean-based approaches are often violated and shows the reduction in statistical power due to subjective discretization. It concludes that PRO-based studies must be conscientiously designed and analyses should consider using ordinal statistical models.
SUPPORTIVE CARE IN CANCER
(2023)
Review
Oncology
C. F. Davies, R. Macefield, K. Avery, J. M. Blazeby, S. Potter
Summary: This systematic review evaluated the development and measurement properties of existing BR patient-reported outcome measures (PROMs) and found that BREAST-Q, BRECON-31, and EORTC QLQ-BRECON-23 have adequate content validity and quality for inclusion in a core measurement set. Discussion with stakeholders is needed to reach a consensus on the recommended PROM for future studies.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Surgery
Viren Patel, Jesse Y. Hsu, Robyn B. Broach, Marty P. Morris, Adrienne N. Christopher, Shelby N. Nathan, Jessica R. Cunning, Benjamin K. Poulose, John P. Fischer
Summary: A novel and accurate method for converting scores between AHQ and HerQLes is presented, facilitating the unification of QoL data from different PROMs. This supports the broader integration of PROMs in surgery and enhances understanding of patient-defined measures of success.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Rehabilitation
Kurt Kroenke, Timothy A. Miksch, Aaron C. Spaulding, Gina L. Mazza, Christopher C. DeStephano, Shehzad K. Niazi, Allie J. Canoy Illies, Mohamad Bydon, Paull Novotny, Anshit Goyal, Minji K. Lee
Summary: This overview addresses key factors and practical decisions related to the use of patient-reported outcome (PRO) measures, as well as highlights clinical decision support issues.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Allergy
Bernardo Sousa-Pinto, Ana Sa-Sousa, Rafael Jose Vieira, Rita Amaral, Ana Margarida Pereira, Josep M. Anto, Ludger Klimek, Wienczyslawa Czarlewski, Joaquim Mullol, Oliver Pfaar, Anna Bedbrook, Luisa Brussino, Violeta Kvedariene, Desiree E. Larenas-Linnemann, Yoshitaka Okamoto, Maria Teresa Ventura, Ignacio J. Ansotegui, Sinthia Bosnic-Anticevich, G. Walter Canonica, Victoria Cardona, Lorenzo Cecchi, Tomas Chivato, Cemal Cingi, Elisio M. Costa, Alvaro A. Cruz, Stefano Del Giacco, Philippe Devillier, Wytske J. Fokkens, Bilun Gemicioglu, Tari Haahtela, Juan Carlos Ivancevich, Piotr Kuna, Igor Kaidashev, Helga Kraxner, Daniel Laune, Renaud Louis, Michael Makris, Riccardo Monti, Mario Morais-Almeida, Ralph Mosges, Marek Niedoszytko, Nikolaos G. Papadopoulos, Vincenzo Patella, Nhan Pham-Thi, Frederico S. Regateiro, Sietze Reitsma, Philip W. Rouadi, Boleslaw Samolinski, Aziz Sheikh, Milan Sova, Luis Taborda-Barata, Sanna Toppila-Salmi, Joaquin Sastre, Ioanna Tsiligianni, Arunas Valiulis, Arzu Yorgancioglu, Mihaela Zidarn, Torsten Zuberbier, Joao A. Fonseca, Jean Bousquet
Summary: This study aimed to calculate cutoff values for visual analog scale (VAS) of global, nasal, ocular, and asthma symptoms in the MASK-air system. The percentile-based approach resulted in lower cutoff values compared to the data-driven approach. Using a data-driven approach, we were able to define cutoff values for MASK-air VASs on allergy and asthma symptoms, allowing for better classification and improved disease management.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2023)
Review
Oncology
Maria Monica Ratti, Giorgio Gandaglia, Eugenia Alleva, Luca Leardini, Elena Silvia Sisca, Alexandra Derevianko, Federica Furnari, Serena Mazzoleni Ferracini, Katharina Beyer, Charlotte Moss, Francesco Pellegrino, Gabriele Sorce, Francesco Barletta, Simone Scuderi, Muhammad Imran Omar, Steven MacLennan, Paula R. Williamson, Jihong Zong, J. MacLennan Sara, Nicolas Mottet, Philip Cornford, Olalekan Lee Aiyegbusi, Mieke Van Hemelrijck, James N'Dow, Alberto Briganti
Summary: This article reviewed and appraised the measurement properties of patient-reported outcome measure questionnaires used for patients with localized prostate cancer. The results indicate that EORTC QLQ-C30 and QLQ-PR25 are recommended tools to measure urinary, bowel, and sexual functions, as well as health-related quality of life, in routine practice and research.
EUROPEAN UROLOGY ONCOLOGY
(2022)
Review
Orthopedics
Eric C. Makhni
Summary: Patient-reported outcome measures (PROMs) provide valuable data for patient-centered health outcome assessment and shared decision-making in clinical care. They play a critical role in monitoring clinical situations, understanding surgical responses, and can also be utilized for clinical research and predictive analytics.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2021)
Article
Medicine, General & Internal
Yongchao Li, Bing Wu, Mao Li, Xiaodong Pang, Liang Yang, Chen Dai, Baogan Peng
Summary: This retrospective study aimed to explore the patient-reported outcome measures (PROM) following coblation nucleoplasty for cervical discogenic dizziness and to compare the therapeutic effect of coblation nucleoplasty with prolonged conservative treatment. The results showed that coblation nucleoplasty significantly improved the symptoms of dizziness and had superior efficacy compared to conservative treatment.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Kritika Yadav, Joline Lim, Joan Choo, Samuel Guan Wei Ow, Andrea Wong, Matilda Lee, Ching Wan Chan, Mikael Hartman, Siew Eng Lim, Natalie Ngoi, Siau Wei Tang, Yvonne Ang, Gloria Chan, Wan Qin Chong, Hon Lyn Tan, Sing Huang Tan, Boon Cher Goh, Soo Chin Lee
Summary: The study compared the anti-angiogenic effects of Sunitinib and Bevacizumab in breast cancer patients, with results showing that Sunitinib significantly increased tumor vessel normalization and decreased lymphatic vessel density, leading to reduced tumor proliferation when used in combination with chemotherapy.
BREAST CANCER RESEARCH AND TREATMENT
(2022)
Article
Rheumatology
Sofie A. M. Gernaat, Julia F. Simard, Anna-Karin Wikstrom, Elisabet Svenungsson, Elizabeth V. Arkema
Summary: The study found a risk association between systemic lupus erythematosus (SLE) and gestational diabetes mellitus (GDM), with women with SLE being more likely to develop GDM during pregnancy compared to general population controls.
JOURNAL OF RHEUMATOLOGY
(2022)
Article
Oncology
Matilda Xinwei Lee, Andrea L. A. Wong, Samuel Ow, Raghav Sundar, David S. P. Tan, Ross A. Soo, Cheng Ean Chee, Joline S. J. Lim, Wei Peng Yong, Siew Eng Lim, Boon Cher Goh, Lingzhi Wang, Soo Chin Lee
Summary: Varlitinib is a potent pan-HER inhibitor with demonstrated activity in various cancers. The study confirmed the safety and efficacy of combining varlitinib with chemotherapy, with the recommended phase II dose being 300 mg twice daily. Subcutaneous trastuzumab can be safely added to this combination for further evaluation in HER2+ breast cancer.
Review
Oncology
Aaron Shengting Mai, Ainsley Ryan Yan Bin Lee, Ryan Yong Kiat Tay, Lauren Shapiro, Astha Thakkar, Balazs Halmos, Albert Grinshpun, Yair Herishanu, Ohad Benjamini, Tamar Tadmor, Rachna T. Shroff, Bonnie J. LaFleur, Deepta Bhattacharya, Siyu Peng, Jeremy Tey, Soo Chin Lee, Louis Yi Ann Chai, Yu Yang Soon, Raghav Sundar, Matilda Xinwei Lee
Summary: This study evaluates the need for booster doses in cancer patients receiving COVID-19 vaccination to improve seroconversion rates. The results show lower seroconversion rates in hematological cancer patients compared to solid cancer patients. Individual patient data analysis also identifies an association between increased duration between the second and third dose, age of the patient, and cancer type with meaningful rise in antibody titres.
EUROPEAN JOURNAL OF CANCER
(2022)
Review
Medicine, General & Internal
Ainsley Ryan Yan Bin Lee, Shi Yin Wong, Louis Yi Ann Chai, Soo Chin Lee, Matilda Xinwei Lee, Mark Dhinesh Muthiah, Sen Hee Tay, Chong Boon Teo, Benjamin Kye Jyn Tan, Yiong Huak Chan, Raghav Sundar, Yu Yang Soon
Summary: This systematic review and meta-analysis compared the efficacy of covid-19 vaccines between immunocompromised and immunocompetent individuals. The results showed that immunocompromised patients, especially organ transplant recipients, had significantly lower rates of seroconversion after covid-19 vaccination. A second dose of the vaccine consistently improved seroconversion in all patient groups, although the improvement was smaller for organ transplant recipients. Targeted interventions, including a third dose (booster) of the vaccine, should be performed for immunocompromised patients.
BMJ-BRITISH MEDICAL JOURNAL
(2022)
Article
Multidisciplinary Sciences
Li-Teng Ong, Wee Chyan Lee, Shijun Ma, Gokce Oguz, Zhitong Niu, Yi Bao, Mubaraka Yusuf, Puay Leng Lee, Jian Yuan Goh, Panpan Wang, Kylie Su Mei Yong, Qingfeng Chen, Wenyu Wang, Adaikalavan Ramasamy, Dave S. B. Hoon, Henrik J. Ditzel, Ern Yu Tan, Soo Chin Lee, Qiang Yu
Summary: In this study, we discovered that IF‑β is highly expressed in HER2(+) breast cancer and inhibits the malignant characteristics of cancer cells by regulating the AKT signaling pathway and XBP1 activation.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Medicine, Research & Experimental
Win Lwin Thuya, Li Ren Kong, Nicholas L. Syn, Ling -Wen Ding, Esther Sok Hwee Cheow, Regina Tong Xin Wong, Tingting Wang, Robby Miguel Wen-Jing Goh, Hongyan Song, Migara K. Jayasinghe, Minh T. N. Le, Jian Cheng Hu, Wei-Peng Yong, Soo-Chin Lee, Andrea Li-Ann Wong, Gautam Sethi, Huynh The Hung, Paul Chi-Lui Ho, Jean-Paul Thiery, Siu Kwan Sze, Tiannan Guo, Ross A. Soo, Henry Yang, Yaw Chyn Lim, Lingzhi Wang, Boon-Cher Goh
Summary: This study reveals that the cargo protein FAM3C carried by tumor-released extracellular vesicles (EVs) can enhance the growth and metastatic potential of lung cancer cells. FAM3C interacts with RalA protein to activate the Src/Stat3 signaling pathway, promoting oncogenicity. This finding provides a new target for lung cancer therapy.
Article
Oncology
Jerold Loh, Jiaxuan Wu, Jenny Chieng, Aurora Chan, Wei-Peng Yong, Raghav Sundar, Soo-Chin Lee, Andrea Wong, Joline S. J. Lim, David S. P. Tan, Ross Soo, Boon-Cher Goh, Bee-Choo Tai, Cheng E. Chee
Summary: Patient selection is crucial in Phase I studies, particularly in heavily pre-treated patients where prognosis estimation is challenging. Existing prognostic models like the Royal Marsden Hospital (RMH) score or the neutrophil-lymphocyte ratio (NLR) have not been validated in current novel therapies or in the Asian Phase I population.
BRITISH JOURNAL OF CANCER
(2023)
Correction
Genetics & Heredity
Ceres Fernandez-Rozadilla, Maria Timofeeva, Zhishan Chen, Philip Law, Minta Thomas, Stephanie Schmit, Virginia Diez-Obrero, Li Hsu, Juan Fernandez-Tajes, Claire Palles, Kitty Sherwood, Sarah Briggs, Victoria Svinti, Kevin Donnelly, Susan Farrington, James Blackmur, Peter Vaughan-Shaw, Xiao-ou Shu, Jirong Long, Qiuyin Cai, Xingyi Guo, Yingchang Lu, Peter Broderick, James Studd, Jeroen Huyghe, Tabitha Harrison, David Conti, Christopher Dampier, Mathew Devall, Fredrick Schumacher, Marilena Melas, Gad Rennert, Mireia Obon-Santacana, Vicente Martin-Sanchez, Ferran Moratalla-Navarro, Jae Hwan Oh, Jeongseon Kim, Sun Ha Jee, Keum Ji Jung, Sun-Seog Kweon, Min-Ho Shin, Aesun Shin, Yoon-Ok Ahn, Dong-Hyun Kim, Isao Oze, Wanqing Wen, Keitaro Matsuo, Koichi Matsuda, Chizu Tanikawa, Zefang Ren, Yu-Tang Gao, Wei-Hua Jia, John Hopper, Mark Jenkins, Aung Ko Win, Rish Pai, Jane Figueiredo, Robert Haile, Steven Gallinger, Michael Woods, Polly Newcomb, David Duggan, Jeremy Cheadle, Richard Kaplan, Timothy Maughan, Rachel Kerr, David Kerr, Iva Kirac, Jan Bohm, Lukka-Pekka Mecklin, Pekka Jousilahti, Paul Knekt, Lauri Aaltonen, Harri Rissanen, Eero Pukkala, Johan Eriksson, Tatiana Cajuso, Ulrika Hanninen, Johanna Kondelin, Kimmo Palin, Tomas Tanskanen, Laura Renkonen-Sinisalo, Brent Zanke, Satu Mannisto, Demetrius Albanes, Stephanie Weinstein, Edward Ruiz-Narvaez, Julie Palmer, Daniel Buchanan, Elizabeth Platz, Kala Visvanathan, Cornelia Ulrich, Erin Siegel, Stefanie Brezina, Andrea Gsur, Peter Campbell, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner, Martha Slattery, John Potter, Konstantinos Tsilidis, Matthias Schulze, Marc Gunter, Neil Murphy, Antoni Castells, Sergi Castellvi-Bel, Leticia Moreira, Volker Arndt, Anna Shcherbina, Mariana Stern, Bens Pardamean, Timothy Bishop, Graham Giles, Melissa Southey, Gregory Idos, Kevin McDonnell, Zomoroda Abu-Ful, Joel Greenson, Katerina Shulman, Flavio Lejbkowicz, Kenneth Offit, Yu-Ru Su, Robert Steinfelder, Temitope Keku, Bethany van Guelpen, Thomas Hudson, Heather Hampel, Rachel Pearlman, Sonja Berndt, Richard Hayes, Marie Elena Martinez, Sushma Thomas, Douglas Corley, Paul Pharoah, Susanna Larsson, Yun Yen, Heinz-Josef Lenz, Emily White, Li Li, Kimberly Doheny, Elizabeth Pugh, Tameka Shelford, Andrew Chan, Marcia Cruz-Correa, Annika Lindblom, David Hunter, Amit Joshi, Clemens Schafmayer, Peter Scacheri, Anshul Kundaje, Deborah Nickerson, Robert Schoen, Jochen Hampe, Zsofia Stadler, Pavel Vodicka, Ludmila Vodickova, Veronika Vymetalkova, Nickolas Papadopoulos, Chistopher Edlund, William Gauderman, Duncan Thomas, David Shibata, Amanda Toland, Sanford Markowitz, Andre Kim, Stephen Chanock, Franzel van Duijnhoven, Edith Feskens, Lori Sakoda, Manuela Gago-Dominguez, Alicja Wolk, Alessio Naccarati, Barbara Pardini, Liesel FitzGerald, Soo Chin Lee, Shuji Ogino, Stephanie Bien, Charles Kooperberg, Christopher Li, Yi Lin, Ross Prentice, Conghui Qu, Stephane Bezieau, Catherine Tangen, Elaine Mardis, Taiki Yamaji, Norie Sawada, Motoki Iwasaki, Christopher Haiman, Loic Le Marchand, Anna Wu, Chenxu Qu, Caroline McNeil, Gerhard Coetzee, Caroline Hayward, Ian Deary, Sarah Harris, Evropi Theodoratou, Stuart Reid, Marion Walker, Li Yin Ooi, Victor Moreno, Graham Casey, Stephen Gruber, Ian Tomlinson, Wei Zheng, Malcolm Dunlop, Richard Houlston, Ulrike Peters
Article
Oncology
Cheng E. Chee, Melissa Ooi, Soo-Chin Lee, Raghav Sundar, Valerie Heong, Wei-Peng Yong, Chin Hin Ng, Andrea Wong, Joline S. J. Lim, David S. P. Tan, Ross Soo, Joshua T. C. Tan, Song Yang, Min Thura, Abdul Qader Al-Aidaroos, Wee Joo Chng, Qi Zeng, Boon-Cher Goh
Summary: This study aims to evaluate the safety and efficacy of PRL3-zumab in patients with advanced solid tumors and hematological malignancies. The results show that PRL3-zumab is safe and tolerable, with stable disease observed in some solid tumor patients.
Meeting Abstract
Oncology
Gwo Fuang Ho, Soo-Chin Lee, Joanna Lim, Anita Zarina Bustam, Siew Eng Lim, Marniza Saad, Samuel Guan Wei Ow, Natalie Ngoi, Nur Fadhlina Abdul Satar, Rozita Abdul Malik, Adlinda Alip, Kian Boon Law, Yok Yong Toh, Jia Wern Pan, Soo Hwang Teo
JOURNAL OF CLINICAL ONCOLOGY
(2022)
Article
Oncology
Joan R. E. Choo, Yi-Hua Jan, Samuel G. W. Ow, Andrea Wong, Matilda Xinwei Lee, Natalie Ngoi, Kritika Yadav, Joline S. J. Lim, Siew Eng Lim, Ching Wan Chan, Mikael Hartman, Siau Wei Tang, Boon Cher Goh, Hon Lyn Tan, Wan Qin Chong, Ang Li En Yvonne, Gloria H. J. Chan, Shu-Jen Chen, Kien Thiam Tan, Soo Chin Lee
Summary: Serial molecular profiling can identify early therapy-induced genomic alterations in HER2-negative breast cancer patients, which may guide the selection of targeted therapies in patients who progress after standard chemotherapy.
Article
Oncology
Jerold Loh, Pei Yi Ong, Denise Li Meng Goh, Mark E. Puhaindran, Balamurugan A. Vellayappan, Samuel Guan Wei Ow, Gloria Chan, Soo-Chin Lee
Summary: Hereditary peripheral nerve sheath tumors (PNSTs) are uncommon in the general population. Through analyzing the clinical characteristics and genetic testing results, NF1 is found to be the most common PNST, and LZTR1 variants may be the underlying cause in Asian patients with multiple schwannomatosis.
HEREDITARY CANCER IN CLINICAL PRACTICE
(2022)
Article
Oncology
Jingshan Ho, Valerie Heong, Wei Peng Yong, Ross Soo, Cheng Ean Chee, Andrea Wong, Raghav Sundar, Yee Liang Thian, Anil Gopinathan, Mei Yan Pang, Priscillia Koe, Santhiay Nathan Jeraj, Phyu Pyar Soe, Mu Yar Soe, Tiffany Tang, Matthew C. H. Ng, David W. M. Tai, Tira J. Y. Tan, Hongmei Xu, Hua Chang, Yosef Landesman, Jatin Shah, Sharon Shacham, Soo Chin Lee, Daniel S. W. Tan, Boon Cher Goh, David S. P. Tan
Summary: This phase 1 study evaluated the tolerability and recommended dose of Selinexor in Asian patients with advanced malignancies. The results showed that a dose of 40 mg/m^2 given twice every 3 weeks was the most tolerable for Asian patients. Selinexor had rapid oral absorption and no PK accumulation.
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY
(2022)
Article
Psychology, Clinical
Eng Hooi Tan, Andrea Li Ann Wong, Chuan Chien Tan, Patrick Wong, Sing Huang Tan, Li En Yvonne Ang, Siew Eng Lim, Wan Qin Chong, Jingshan Ho, Soo Chin Lee, Bee Choo Tai
Summary: The study validated the Beliefs about Medicines Questionnaire (BMQ) and Adherence Starts with Knowledge (ASK-12) questionnaire for use in a Singapore population with early stage breast cancer. The new factor structure obtained from exploratory factor analysis improved the internal consistency of BMQ-General and ASK-12 Behaviour scale. Further studies are required to confirm these factor structures.
JOURNAL OF HEALTH PSYCHOLOGY
(2022)