Modeling of Aniridia-Related Keratopathy by CRISPR/Cas9 Genome Editing of Human Limbal Epithelial Cells and Rescue by Recombinant PAX6 Protein

Human aniridia limbal epithelial cells lack expression of keratins K3 and K12

(2018) Lorenz Latta et al.   EXPERIMENTAL EYE RESEARCH

PAX6: 25th anniversary and more to learn

(2017) Ales Cvekl et al.   EXPERIMENTAL EYE RESEARCH

Toward a CRISPR Picture: Use of CRISPR/Cas9 to Model Diseases in Human Stem Cells In Vitro

(2017) Jamie L. Freiermuth et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Efficacy of Postnatal In Vivo Nonsense Suppression Therapy in a Pax6 Mouse Model of Aniridia

(2017) Xia Wang et al.   Molecular Therapy-Nucleic Acids

Induced pluripotent stem cell-derived limbal epithelial cells (LiPSC) as a cellular alternative for in vitro ocular toxicity testing

(2017) Edith Aberdam et al.   PLoS One

Applications and Challenges for Use of Cell-Penetrating Peptides as Delivery Vectors for Peptide and Protein Cargos

(2016) Mie Kristensen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Disruption of Autoregulatory Feedback by a Mutation in a Remote, Ultraconserved PAX6 Enhancer Causes Aniridia

(2013) Shipra Bhatia et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Concise Review: Hurdles in a Successful Example of Limbal Stem Cell-based Regenerative Medicine

(2013) Graziella Pellegrini et al.   STEM CELLS

Pluripotent Stem Cell Model Reveals Essential Roles for miR-450b-5p and miR-184 in Embryonic Corneal Lineage Specification

(2012) Ruby Shalom-Feuerstein et al.   STEM CELLS

Corneal stem cells in the eye clinic

(2011) Alex J. Shortt et al.   BRITISH MEDICAL BULLETIN

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Genetic analysis of chromosome 11p13 and thePAX6 gene in a series of 125 cases referred with aniridia

(2008) David O. Robinson et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

PAX6 dosage effects on corneal development, growth, and wound healing

(2008) Natalie Dorà et al.   DEVELOPMENTAL DYNAMICS

Relationship of Pax6 Activity Levels to the Extent of Eye Development in the Mouse, Mus musculus

(2008) J. Favor et al.   GENETICS

Corneal Epithelial Stem Cells: Deficiency and Regulation

(2008) Genevieve A. Secker et al.   Stem Cell Reviews and Reports