期刊
SENSORS AND ACTUATORS B-CHEMICAL
卷 273, 期 -, 页码 689-695出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2018.06.119
关键词
Silver nanowires; Immunoassay complex; Fluorescence imaging; Dynamic sensing
资金
- National Science Centre Poland [2016/21/B/ST3/02276, DEC-2013/10/E/ST3/00034]
- City of Gdynia, Poland [3/DOT/2016]
We demonstrate fast and simple route to selective virus detection using antibody-functionalized silver nano wires. While the immunocomplex formation takes place in solution, the presence of viruses is determined by correlating transmission and fluorescence images obtained after depositing nanowire solution on a substrate. Importantly, by mixing nanowires in solution we expect to substantially increase the probability for immunocomplex formation, as evidenced by almost complete capturing of viruses after overnight incubation. This approach, based on dynamic search for viruses in solution, gives the possibility to reach medically relevant detection level of 10(3) pfu/ml, which translates to just 5 bacteriophages in a test volume of 5 mu l.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据