Article
Chemistry, Analytical
Dan Cheng, Xiang Liu, Peipei Li, Youyu Zhang, Meiling Liu, Shouzhuo Yao
Summary: In this study, a novel ratiometric electrochemical sensor for uric acid (UA) was developed using Cu2O nanocubes and boron carbide (B4C) as the sensing materials. The sensor detected UA concentration by measuring the ratio between the oxidation peak of UA and the reference peak of Cu2O.
Article
Materials Science, Multidisciplinary
Nagaraj Murugan, Rajendran Jerome, Murugan Preethika, Anandhakumar Sundaramurthy, Ashok K. Sundramoorthy
Summary: This study reports the synthesis of mixed phase 2D MXene as a catalytic material for simultaneous detection of important biomolecules such as AA, DA and UA. The Ti-C-T-x modified GCE showed excellent electrocatalytic activity and separated oxidation peaks, enabling the simultaneous detection of these biomolecules with high sensitivity and stability.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2021)
Article
Electrochemistry
Keerakit Kaewket, Chanpen Karuwan, Somchai Sonsupap, Santi Maensiri, Kamonwad Ngamchuea
Summary: In this study, carbon nanofibers (CNF) were synthesized by electrospinning and their anti-fouling properties were demonstrated. The synthesized CNF was characterized using various techniques, and different electrode preparation methods were tested. The electrochemical behaviors of CNF towards various systems were explored, highlighting the material's potential applications.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Wenli Hou, Xianyu Kang, Jiajie Lin, Mengying Xie, Yancai Li
Summary: In this study, bagasse derived nitrogen-doped activated carbon was prepared and gold nanoparticles were successfully loaded onto the carbon to form nanocomposites. The composite exhibited excellent electrocatalytic performance and could be used as a novel electrochemical sensor for the detection of 4-aminophenol.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Nanoscience & Nanotechnology
Fang-Hui Wu, Mei-Juan Ren, Miao Wang, Wen-Bin Sun, Kong-Lin Wu, Yuan-Sheng Cheng, Zhengquan Yan
Summary: In this study, one-dimensional nitrogen doped porous carbon nano-arrays arranged by carbon nanotube (1D CNTs@NPC) were constructed and used to modify glassy carbon electrodes for the detection of ascorbic acid, dopamine, and uric acid. The resulting electrodes showed excellent analytical performance with low detection limits and high stability and selectivity when applied to real samples. This work provides potential for efficient diagnosis of ascorbic acid, dopamine, or uric acid-related diseases in clinical testing in the future.
Article
Chemistry, Analytical
Jing Guo, Lihua Wu, Yu-Xin Ye, Fang Zhu, Jianqiao Xu, Gangfeng Ouyang
Summary: Two-dimensional (2D) conductive metal-organic frameworks (cMOFs) have been used as transducers for electrochemical sensing, but its application in aqueous solutions is in the early stage. This study utilizes the interfacial capacitances of a 2D cMOF for the first time in electrochemical sensing. Various compounds, including redox-innocent and redox-active compounds, are successfully detected based on the responses of capacitance peaks at low voltages. The insights into the response mechanisms represent an important step in promoting the application of 2D cMOFs in chemical sensing.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Jing Guo, Lihua Wu, Yu-Xin Ye, Fang Zhu, Jianqiao Xu, Gangfeng Ouyang
Summary: Two-dimensional conductive metal-organic frameworks (cMOFs) have been used for electrochemical sensing, but their application in aqueous solutions is still in the early stage. In this study, the interfacial capacitances of a 2D cMOF are utilized for electrochemical sensing for the first time and successfully detect various compounds in aqueous solutions. The responses are rooted in the pseudocapacitances of the 2D cMOF, revealing deep insights into the response mechanisms and promoting the application of 2D cMOFs in chemical sensing.
ANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Electrical & Electronic
Ajay P. Khairnar, Anita K. Tawade, Bhagyashri B. Kamble, Hemant S. Khune, Anil A. Powar, Kirankumar K. Sharma, Manohar R. Patil, Shivaji N. Tayade, Vijay S. Patil
Summary: An immensely selective sensor TiO2-ZnO-BMIMBr nanocomposite was developed for dopamine detection. Ionic liquids (ILs) act as green dispersing media for the nanostructures, enhancing conductivity and biocompatibility. The nanocomposite exhibits improved electrochemical behavior compared to the bare electrode, and has a low detection limit for dopamine in urine samples.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2023)
Article
Materials Science, Multidisciplinary
Cheng-Hui Shen, Yu-Na Chang, You-Liang Chen, Chung-Wei Kung
Summary: A highly porous and chemically stable metal-organic framework (MOF) with enriched sulfonate groups, SO3-MOF-808, is synthesized and proposed as a porous alternative to Nafion for modulating the selectivity of electrochemical reactions. The use of SO3-MOF-808 thin film as an electrode coating significantly improves the current signal for dopamine oxidation and the selectivity against interfering compounds.
ACS MATERIALS LETTERS
(2023)
Article
Chemistry, Analytical
Jingjing Jiang, Dong Ding, Jing Wang, Xinyi Lin, Guowang Diao
Summary: Three-dimensional nitrogen-doped graphene networks were used as building blocks to construct a metal-free quadruplet electrochemical sensor for simultaneous detection of AA, DA, UA, and AP. The 3D-NG materials with a porous structure and nitrogen doping effect had improved electrocatalytic activities, allowing for effective differentiation of the four analytes.
Article
Chemistry, Analytical
Jinjing Han, Justin M. Stine, Ashley A. Chapin, Reza Ghodssi
Summary: In this study, a novel, simple, and low-cost electrochemical sensing platform was developed for the detection of serotonin (5-HT) in artificial biological fluids. The platform utilized Nafion/carbon nanotubes and electrochemically modified carbon fiber microelectrodes to enhance the sensitivity and selectivity of 5-HT. With a customized Ag/AgCl reference electrode and Pt counter electrode, the portable 5-HT sensing platform demonstrated a sensitivity of 0.074 mu A mu M-1 and a limit of detection (LOD) of 140 nM. The system was also capable of accurately measuring 5-HT spiked in artificial urine samples, showing nearly full recovery rates.
ANALYTICAL METHODS
(2023)
Article
Multidisciplinary Sciences
Pattan-Siddappa Ganesh, Sang-Youn Kim, Savas Kaya, Rajae Salim
Summary: This study utilized DFT to analyze the molecular structure and energy levels of surfactant-modified electrodes. The modified electrode successfully resolved the overlapping oxidation signals of isomers and showed feasibility in analyzing specific substances in water samples. This lays a new foundation for fabricating electrochemical sensors.
SCIENTIFIC REPORTS
(2022)
Article
Materials Science, Multidisciplinary
Anoop Singh, Asha Sharma, Aamir Ahmed, Sandeep Arya
Summary: A nanocomposite of CuO/rGO was prepared and used for the electrochemical modification of ascorbic acid. The synergistic effect of CuO/rGO showed highly electrocatalytic activity towards the oxidation of ascorbic acid. The electrochemical sensor exhibited a wide linear response and low detection limit, as well as good stability, reproducibility, and specificity.
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
(2022)
Article
Chemistry, Physical
Mingyue Wang, Hao Guo, Ning Wu, Junye Zhang, Tinging Zhang, Bingqing Liu, Zhilan Pan, Liping Peng, Wu Yang
Summary: A novel triazine-based covalent organic framework and its composite were successfully constructed by in situ growth of gold nanoparticles on its surface, followed by introduction of reduced graphene oxide. The constructed nanocomposite modified electrode exhibited excellent conductivity and catalytic activity, allowing for simultaneous detection of uric acid, dopamine, and ascorbic acid in urine samples accurately and rapidly.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Analytical
Tongtong Cao, Yicheng Zhou, Haoran Wang, Rongrong Qiao, Xiaobo Zhang, Lin Liu, Zhiwei Tong
Summary: A sandwich-structured composite material for simultaneous detection of ascorbic acid and dopamine was successfully synthesized by intercalating a polyfluorinated cationic azobenzene derivative into a layer semiconductor. The composite material exhibited good structural and compositional features, and showed effective detection of the target substances under saturated conditions.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)