Article
Engineering, Environmental
Jiaqi Zhang, Christopher Hurren, Zhentan Lu, Dong Wang
Summary: This research presents a simple nanofiber-based platform for highly sensitive colorimetric/fluorometric detection of Escherichia coli (E. coli) in complex environmental samples. The nanofiber membranes loaded with target molecules via chemical modification can produce biological signals and color change triggered by beta-glucuronidase secreted by E. coli. The nanofiber-based platforms exhibited high stability, a wide detection range, high specificity, and low interference, making them promising for environmental and food safety testing. The combination with a smartphone app enables on-site detection of E. coli.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Analytical
Meng Meng, Ying Jiang, Wang Li, Qian Wen, Ying Xiong, Qi Chen, Jiali Ren
Summary: In this study, a rapid and sensitive detection method for E. coli based on M13K07 phage was reported. The method was able to detect as low as 4 cfu/mL of E. coli in a short period of time, and specific analysis and practical application were successfully confirmed.
MICROCHEMICAL JOURNAL
(2023)
Article
Engineering, Electrical & Electronic
N. Mohd Amin, Y. Mustapha Kamil, N. H. Zainol Abidin, F. H. Mustafa, M. H. Abu Bakar
Summary: This study reports the enhancement of a single-mode tapered optical fiber sensor for detecting Dengue virus II E protein using chitosan, an organic nanomaterial. Optimal DENV sensing performance was achieved at a chitosan thickness of 17.13 nm, leading to improved sensitivity and affinity compared to standard configuration sensors. The findings highlight the potential of organic nanomaterials like chitosan for biosensor enhancement and emphasize the capability of fiber optic sensors for disease detection.
IEEE SENSORS JOURNAL
(2021)
Article
Chemistry, Analytical
Yuan Yao, Guoming Xie, Xin Zhang, Jinshan Yuan, Yulei Hou, Hui Chen
Summary: A turn-on fluorescent biosensor based on a FRET system was developed for rapid detection of E. coli using synthesized UCNPs and GO@Fe3O4, showing precise and practical capabilities for clinical application in complex biological samples.
ANALYTICAL METHODS
(2021)
Article
Engineering, Environmental
Toktam Ghadam Soltani, Mansour Mashreghi, Mohammad Reza Housaindokht, Mohamad Hosein Mahmudy Gharaie
Summary: Current arsenic analysis methods in groundwater samples are expensive and complex, leading to delays in detecting arsenic harm. This study optimized a bioluminescent biosensor to detect and measure arsenic in water, showing promising results in a certain concentration range but with toxic effects at higher levels. The use of a modified Gompertz model successfully predicted biosensor growth and highlighted the importance of this environmentally friendly tool with high sensitivity.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
(2021)
Article
Engineering, Electrical & Electronic
Yan Yang, Shuguo Xie, Yakai Dong, Tianheng Wang, Xin Zhao
Summary: The paper proposes a universal frequency recovery algorithm based on the Remainder Matching (RM) technique, suitable for both large and small frequency differences. The method determines the exact remainder combination in the first repetition frequency intervals using RM technique and calculates the measured frequency. The paper also presents the theoretical basis of RM and summarizes the system design rules, which significantly impact the performance of the measurement system.
IEEE SENSORS JOURNAL
(2021)
Article
Chemistry, Analytical
Abdus Sobhan, Fei Jia, Lisa Cooney Kelso, Sonatan Kumar Biswas, Kasiviswanathan Muthukumarappan, Changyong Cao, Lin Wei, Yanbin Li
Summary: An activated biochar-based immunosensor was developed to rapidly detect E. coli O157:H7 cells without incubation. The sensor coated with activated biochar and functionalized with antibodies showed enhanced impedance amplitude compared to the control electrode. The immunosensor was capable of detecting E. coli O157:H7 cells with a limit of detection of 4 log CFU/mL.
Article
Chemistry, Analytical
Nan Li, Weifei Zhang, Jing Lin, Gaowa Xing, Haifang Li, Jin-Ming Lin
Summary: This article introduces a method for simultaneous detection of multiple bacteria using mass tag-mediated surface engineering and mass spectrometry. This method eliminates the need for reliance on microbial mass spectra databases and shows potential application in milk safety monitoring.
ANALYTICAL CHEMISTRY
(2022)
Article
Optics
Nur Diyana Jamaluddin, Nadiah Ibrahim, Nurul Yuziana Mohd Yusof, Choo Ta Goh, Ling Ling Tan
Summary: A reflectometric-based RNA biosensor using cysteamine-stabilized gold nanoparticles as colorimetric probes was developed for the bioassay of COVID-19 RNA. This sensor showed rapid response time, high sensitivity, and good reproducibility, making it useful for early diagnosis of COVID-19 disease.
OPTICS AND LASER TECHNOLOGY
(2023)
Article
Engineering, Electrical & Electronic
Treesukon Treebupachatsakul, Chanin Lochotinunt, Thitirat Teechot, Nattha Pensupa, Suejit Pechprasarn
Summary: This study used fluorescence measurement to quantify the number of E. coli colonies by the catalytic reaction between GUD secreted by E. coli and its substrate MUG, resulting in the production of 4MU. A simple instrument was proposed for label-free, real-time, in-situ, and quantitative E. coli measurement, utilizing cost-effective and eco-friendly gelatin microfluidic channels fabricated with a laser printer.
IEEE SENSORS JOURNAL
(2022)
Review
Optics
Pengqi Gong, Xuegang Li, Xue Zhou, Yanan Zhang, Ning Chen, Shankun Wang, Siqi Zhang, Yong Zhao
Summary: The paper provides a brief overview of the current research progress of optical fiber glucose sensor (OFGS), including detection principles and measurement methods, as well as discussing its shortcomings and future prospects.
OPTICS AND LASER TECHNOLOGY
(2021)
Review
Chemistry, Analytical
Marjan Majdinasab, Marc Lamy de la Chapelle, Jean Louis Marty
Summary: Interleukin 6 (IL-6) is a pleiotropic cytokine that exerts pathological pro-inflammatory effects and plays important roles in various biological processes. The detection of IL-6 in small quantities with high selectivity is crucial in medical and biological fields. Conventional laboratory methods such as ELISAs and CLIAs are complex, expensive, and time-consuming, while biosensors offer a simple, rapid, economical, and user-friendly alternative due to their high sensitivity, quick detection time, ease of use, and miniaturization capability.
Article
Food Science & Technology
Azam Bagheri Pebdeni, Amirreza Roshani, Ensiyeh Mirsadoughi, Shakila Behzadifar, Morteza Hosseini
Summary: Identifying pathogens in food and drinking water is crucial, and new nano technology methods based on optical methods have provided cheaper, more reliable, faster, and more sensitive platforms for detecting E. coli. Various optical methods are available for the detection of E. coli.
Article
Spectroscopy
Hyeong-Min Kim, Jae-Hyoung Park, Seung-Ki Lee
Summary: FO LSPR sensors are limited by the small area of the substrate, and enhancing interactions between plasmonic nanostructures can improve sensor sensitivity. By using dimers, the interaction between light and nanostructures is effectively increased, resulting in improved performance of the FO LSPR sensors.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Review
Chemistry, Analytical
Reza Eivazzadeh-Keihan, Zahra Saadatidizaji, Ali Maleki, Miguel de la Guardia, Mohammad Mahdavi, Sajjad Barzegar, Samad Ahadian
Summary: Thrombin is a serine protease that plays a crucial role in blood clotting and homeostasis. Detecting thrombin quickly and accurately is important for biological analysis and clinical diagnosis. Various biosensors have been developed to achieve highly selective and specific detection of thrombin. Aptasensors, which use DNA or RNA aptamers as biological recognition elements, have shown great sensitivity and affinity in identifying thrombin.
Article
Chemistry, Multidisciplinary
Yuri S. Pestovsky, Agustino Martinez-Antonio
Article
Biotechnology & Applied Microbiology
Alberto Camas-Reyes, Ricardo Laguna-Ramirez, Alba E. Jofre-Garfias, Faviola Cardoso-Martinez, Ana Lilia Hernandez-Orihuela, Jorge Molina-Torres, Agustino Martinez-Antonio
PLANT CELL TISSUE AND ORGAN CULTURE
(2019)
Article
Chemistry, Applied
S. Espinel-Rios, D. M. Palmerin-Carreno, A. L. Hernandez-Orihuela, A. Martinez-Antonio
REVISTA MEXICANA DE INGENIERIA QUIMICA
(2019)
Review
Microbiology
Ismael Sanchez-Osorio, Carlos Andres Hernandez-Martinez, Agustino Martinez-Antonio
CURRENT OPINION IN MICROBIOLOGY
(2020)
Article
Biotechnology & Applied Microbiology
Estefania Sierra-Ibarra, Laura J. Leal-Reyes, Gerardo Huerta-Beristain, Ana L. Hernandez-Orihuela, Guillermo Gosset, Agustino Martinez-Antonio, Alfredo Martinez
Summary: The study found that micro-aeration significantly increased the rate and yield of lactate production by engineered Escherichia coli, without compromising lactate yield. A suitable volumetric oxygen transfer coefficient can be successfully used to scale up lactate production, and high productivity and yield can also be achieved in different culture media.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2021)
Article
Multidisciplinary Sciences
Cynthia Paola Rangel-Chavez, Edgardo Galan-Vasquez, Azucena Pescador-Tapia, Luis Delaye, Agustino Martinez-Antonio
Summary: This study analyzed the RNA polymerase subunits in endosymbiont bacteria with extreme genome reductions, revealing that the catalytic core and assembly domains of the β and β' subunits are highly conserved, while the sigma subunit shows the most erosive diversity.
Review
Plant Sciences
Karla S. Macedo-Osorio, Agustino Martinez-Antonio, Jesus A. Badillo-Corona
Summary: Penta-, Tetra-, and Octo-tricopeptide repeat (PPR, TPR, and OPR) proteins play important roles in RNA stabilization, processing, and translation in chloroplasts and mitochondria. While PPR proteins are abundant in plants, OPR proteins are more prevalent in algae. Research has shown that PPR proteins have been extensively characterized, but further investigation into the helical repeat proteins code in algae is needed.
FRONTIERS IN PLANT SCIENCE
(2021)
Review
Biochemistry & Molecular Biology
Maria del Rosario Cardenas-Aquino, Yohanna Sarria-Guzman, Agustino Martinez-Antonio
Summary: Shoot branching is a crucial event in plant development, which is regulated by cytokinins, strigolactones, and auxins. Cytokinins promote shoot branching by activating axillary buds, while strigolactones and auxins inhibit bud outgrowth. The involvement of aromatic and isoprenoid cytokinins in shoot branching, as well as the contribution of auxins and strigolactones to this process, is discussed in this review. However, there are still many questions regarding the regulation of the BRC1 gene expression by cytokinins and strigolactones, as well as the interaction among cytokinins, auxins, and strigolactones.
Article
Chemistry, Applied
F. Martinez-Moreno, A. E. Jofre y Garfias, A. L. Hernandez-Orihuela, A. Martinez-Antonio
Summary: This study tested the suitability of using avocado seed hydrolysates as a growth medium for cultivating fungal isolates from strawberry plants. Results showed that ASM is a competitive and suitable medium for fungal growth, offering an alternative to traditional media like PDA and V8.
REVISTA MEXICANA DE INGENIERIA QUIMICA
(2021)
Meeting Abstract
Cardiac & Cardiovascular Systems
Ana C. Marquez-Sanchez, Alejandro Manzanares-Guzman, Dannia Colin-Castelan, Dalia Rodriguez-Rios, Enrique Ramirez-Chavez, Jorge Molina-Torres, Gloria Barbosa-Sabanero, Agustino Martinez-Antonio, Yolanda Alvarado-Caudillo, Gertrud Lund, Ramon Carriles-Jaimes, Lino Sanchez-Segura, Silvio Zaina
AMERICAN HEART JOURNAL
(2020)
Article
Mathematical & Computational Biology
Edgardo Galan-Vasquez, Beatriz Carely Luna-Olivera, Marcelino Ramirez-Ibanez, Agustino Martinez-Antonio
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
(2020)
Article
Biotechnology & Applied Microbiology
Dulce Maria Palmerin-Carreno, Ana Lilia Hernandez-Orihuela, Agustino Martinez-Antonio
FERMENTATION-BASEL
(2019)
Proceedings Paper
Engineering, Manufacturing
Y. S. Pestovsky, A. Martinez-Antonio
2018 2ND INTERNATIONAL CONFERENCE ON ADVANCED TECHNOLOGIES IN MANUFACTURING AND MATERIALS ENGINEERING (ATMME 2018)
(2018)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)