MEG3-4 is a miRNA decoy that regulates IL-1β abundance to initiate and then limit inflammation to prevent sepsis during lung infection

A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation

(2016) Maninjay K. Atianand et al.   CELL

Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins

(2016) Sungyul Lee et al.   CELL

Type I CRISPR-Cas targets endogenous genes and regulates virulence to evade mammalian host immunity

(2016) Rongpeng Li et al.   CELL RESEARCH

MicroRNAs Constitute a Negative Feedback Loop inStreptococcus pneumoniae–Induced Macrophage Activation

(2016) Kathrin Griss et al.   JOURNAL OF INFECTIOUS DISEASES

Pseudomonas aeruginosa infection augments inflammation through miR-301b repression of c-Myb-mediated immune activation and infiltration

(2016) Xuefeng Li et al.   Nature Microbiology

Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy

(2016) Kamlesh Pawar et al.   Scientific Reports

MiR-141 Inhibits Gastric Cancer Proliferation by Interacting with Long Noncoding RNA MEG3 and Down-Regulating E2F3 Expression

(2015) Xiaoying Zhou et al.   DIGESTIVE DISEASES AND SCIENCES

Annexin A2 Regulates Autophagy inPseudomonas aeruginosaInfection through the Akt1–mTOR–ULK1/2 Signaling Pathway

(2015) Rongpeng Li et al.   JOURNAL OF IMMUNOLOGY

Chromatin and RNA Maps Reveal Regulatory Long Noncoding RNAs in Mouse

(2015) Gireesh K. Bogu et al.   MOLECULAR AND CELLULAR BIOLOGY

MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures

(2015) Tanmoy Mondal et al.   Nature Communications

An IL6-STAT3 loop mediates resistance to PI3K inhibitors by inducing epithelial–mesenchymal transition and cancer stem cell expansion in human breast cancer cells

(2014) Lin Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis

(2014) Yong He et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Long noncoding RNA are aberrantly expressed in vivo in the cystic fibrosis bronchial epithelium

(2014) Paul J. McKiernan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

MiR-148a regulates MEG3 in gastric cancer by targeting DNA methyltransferase 1

(2014) Jiang Yan et al.   MEDICAL ONCOLOGY

The Long Non-Coding RNA GAS5 Cooperates with the Eukaryotic Translation Initiation Factor 4E to Regulate c-Myc Translation

(2014) Guangzhen Hu et al.   PLoS One

MicroRNA-302b augments host defense to bacteria by regulating inflammatory responses via feedback to TLR/IRAK4 circuits

(2014) Xikun Zhou et al.   Nature Communications

Long Non-Coding RNAs Involved in Immune Responses

(2014) Katsutoshi Imamura et al.   Frontiers in Immunology

Long non-coding RNA MEG3 inhibits NSCLC cells proliferation and induces apoptosis by affecting p53 expression

(2013) Kai-hua Lu et al.   BMC CANCER

Long noncoding RNAs in innate and adaptive immunity

(2013) Katherine A. Fitzgerald et al.   CURRENT OPINION IN IMMUNOLOGY

A Long Noncoding RNA Mediates Both Activation and Repression of Immune Response Genes

(2013) S. Carpenter et al.   SCIENCE

MicroRNA-feedback loop as a key modulator of liver tumorigenesis and inflammation

(2013) Angélique Gougelet   WORLD JOURNAL OF GASTROENTEROLOGY

A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics

(2013) Nicole A Rapicavoli et al.   eLife

Long non-coding RNAgadd7interacts with TDP-43 and regulatesCdk6mRNA decay

(2012) Xuefeng Liu et al.   EMBO JOURNAL

Overexpression of the long non-coding RNA MEG3 impairs in vitro glioma cell proliferation

(2012) Pengjun Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Posttranscriptional Gene Regulation by Long Noncoding RNA

(2012) Je-Hyun Yoon et al.   JOURNAL OF MOLECULAR BIOLOGY

Development of Plasmid Calibrators for Absolute Quantification of miRNAs by Using Real-Time qPCR

(2012) Christine Formisano-Tréziny et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA

(2011) Marcella Cesana et al.   CELL

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

Expression of DLK1 and MEG3 genes in porcine tissues during postnatal development

(2011) Maria Oczkowicz et al.   GENETICS AND MOLECULAR BIOLOGY

microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer

(2011) C Braconi et al.   ONCOGENE

Maternally Expressed Gene 3, an Imprinted Noncoding RNA Gene, Is Associated with Meningioma Pathogenesis and Progression

(2010) X. Zhang et al.   CANCER RESEARCH

Increased Expression of Angiogenic Genes in the Brains of MouseMeg3-Null Embryos

(2010) Francesca E. Gordon et al.   ENDOCRINOLOGY

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

(2010) Sabine Loewer et al.   NATURE GENETICS

IL-1β Processing in Host Defense: Beyond the Inflammasomes

(2010) Mihai G. Netea et al.   PLoS Pathogens

A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster

(2009) X. Zhang et al.   BLOOD

Maternally Expressed Gene 3 (MEG3) Noncoding Ribonucleic Acid: Isoform Structure, Expression, and Functions

(2009) Xun Zhang et al.   ENDOCRINOLOGY

Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps

(2009) Sung Wook Chi et al.   NATURE

Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins

(2009) Bingbing Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alveolar Epithelial Type II Cells Activate Alveolar Macrophages and Mitigate P. Aeruginosa Infection

(2009) Shibichakravarthy Kannan et al.   PLoS One

Cell death in the host response to infection

(2008) K Labbé et al.   CELL DEATH AND DIFFERENTIATION

IL-1, IL-18, and IL-33 families of cytokines

(2008) William P. Arend et al.   IMMUNOLOGICAL REVIEWS