A hierarchy of affinities between cytokine receptors and the common gamma chain leads to pathway cross-talk

Essential role of endocytosis for interleukin-4-receptor-mediated JAK/STAT signalling

(2015) K. Kurgonaite et al.   JOURNAL OF CELL SCIENCE

Targeted Proteomics-Driven Computational Modeling of Macrophage S1P Chemosensing

(2015) Nathan P. Manes et al.   MOLECULAR & CELLULAR PROTEOMICS

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency

(2015) Ignacio Moraga et al.   Science Signaling

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency

(2015) Ignacio Moraga et al.   Science Signaling

NetworkViewer: visualizing biochemical reaction networks with embedded rendering of molecular interaction rules

(2014) Hsueh-Chien Cheng et al.   BMC Systems Biology

TCR Microclusters Pre-Exist and Contain Molecules Necessary for TCR Signal Transduction

(2014) T. J. Crites et al.   JOURNAL OF IMMUNOLOGY

The Simmune Modeler visual interface for creating signaling networks based on bi-molecular interactions

(2013) Fengkai Zhang et al.   BIOINFORMATICS

Soluble IL7R  potentiates IL-7 bioactivity and promotes autoimmunity

(2013) W. Lundstrom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-to-Cell Variability Analysis Dissects the Plasticity of Signaling of Common   Chain Cytokines in T Cells

(2013) J. W. Cotari et al.   Science Signaling

The role of the T follicular helper cells in allergic disease

(2012) DM Kemeny   Cellular & Molecular Immunology

Role of the common   chain in cell cycle progression of human malignant cell lines

(2012) I. Vigliano et al.   INTERNATIONAL IMMUNOLOGY

Cytokines of the γc family control CD4+ T cell differentiation and function

(2012) Hidehiro Yamane et al.   NATURE IMMUNOLOGY

Computational modeling of cellular signaling processes embedded into dynamic spatial contexts

(2012) Bastian R Angermann et al.   NATURE METHODS

Structural reorganization of the interleukin-7 signaling complex

(2012) C. A. McElroy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins

(2012) Travis J. Crites et al.   Jove-Journal of Visualized Experiments

Single Cell Analysis of Ligand Binding and Complex Formation of Interleukin-4 Receptor Subunits

(2011) Thomas Weidemann et al.   BIOPHYSICAL JOURNAL

Interleukin-7 Receptor Signaling Network: An Integrated Systems Perspective

(2010) Megan J Palmer et al.   Cellular & Molecular Immunology

In vivo regulation of the allergic response by the IL-4 receptor α chain immunoreceptor tyrosine-based inhibitory motif

(2010) Raffi Tachdjian et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Interleukin-7 Compartmentalizes Its Receptor Signaling Complex to Initiate CD4 T Lymphocyte Response

(2010) Thierry Rose et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Implications for Gene Therapy-Limiting Expression of IL-2R c Delineate Differences in Signaling Thresholds Required for Lymphocyte Development and Maintenance

(2010) S. J. Orr et al.   JOURNAL OF IMMUNOLOGY

Coupling Mechanism of a GPCR and a Heterotrimeric G Protein During Chemoattractant Gradient Sensing in Dictyostelium

(2010) X. Xu et al.   Science Signaling

The Cellular Amount of the Common  -Chain Influences Spontaneous or Induced Cell Proliferation

(2009) S. Amorosi et al.   JOURNAL OF IMMUNOLOGY

The Complexity of Cell Signaling and the Need for a New Mechanics

(2009) W. S. Hlavacek et al.   Science Signaling

Structural and Biophysical Studies of the Human IL-7/IL-7Rα Complex

(2009) Craig A. McElroy et al.   STRUCTURE

Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System

(2008) Sherry L. LaPorte et al.   CELL

Protein tyrosine phosphatases in the JAK/STAT pathway

(2008) Dan Xu   Frontiers in Bioscience-Landmark

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

(2008) Steven J. Howe et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural Biology of Shared Cytokine Receptors

(2007) Xinquan Wang et al.   Annual Review of Immunology