Jak-TGFβ cross-talk links transient adipose tissue inflammation to beige adipogenesis

IP-receptor and PPARs trigger the conversion of human white to brite adipocyte induced by carbaprostacyclin

(2016) Rayane A. Ghandour et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Pdgfrβ+ Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat-Diet Feeding and Prolonged Cold Exposure in Adult Mice

(2016) Lavanya Vishvanath et al.   Cell Metabolism

Oncostatin m impairs brown adipose tissue thermogenic function and the browning of subcutaneous white adipose tissue

(2016) David Sánchez-Infantes et al.   Obesity

MDM2 facilitates adipocyte differentiation through CRTC-mediated activation of STAT3

(2016) P Hallenborg et al.   Cell Death & Disease

The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention

(2015) John J. O'Shea et al.   Annual Review of Medicine

Myocardin-Related Transcription Factor A Regulates Conversion of Progenitors to Beige Adipocytes

(2015) Meghan E. McDonald et al.   CELL

Browning of Subcutaneous White Adipose Tissue in Humans after Severe Adrenergic Stress

(2015) Labros S. Sidossis et al.   Cell Metabolism

Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice

(2015) Gabriele Schoiswohl et al.   ENDOCRINOLOGY

Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis

(2015) Labros Sidossis et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity

(2015) Elise Jeffery et al.   NATURE CELL BIOLOGY

Transcriptional Pathways in cPGI2-Induced Adipocyte Progenitor Activation for Browning

(2015) Irem Bayindir et al.   Frontiers in Endocrinology

Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation

(2015) Samadhi Aparicio-Siegmund et al.   Oncotarget

Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat

(2014) Yifu Qiu et al.   CELL

Adipocyte Inflammation Is Essential for Healthy Adipose Tissue Expansion and Remodeling

(2014) Ingrid Wernstedt Asterholm et al.   Cell Metabolism

Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation

(2014) Emilio P. Mottillo et al.   JOURNAL OF LIPID RESEARCH

Thermogenic adipocytes: From cells to physiology and medicine

(2014) Mauricio Berriel Diaz et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

White-to-brown metabolic conversion of human adipocytes by JAK inhibition

(2014) Annie Moisan et al.   NATURE CELL BIOLOGY

Regulation of MKL1 via actin cytoskeleton dynamics drives adipocyte differentiation

(2014) Hiroyuki Nobusue et al.   Nature Communications

The role of JAK–STAT signaling in adipose tissue function

(2013) Allison J. Richard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Identification of an Adipogenic Niche for Adipose Tissue Remodeling and Restoration

(2013) Yun-Hee Lee et al.   Cell Metabolism

Tracking adipogenesis during white adipose tissue development, expansion and regeneration

(2013) Qiong A Wang et al.   NATURE MEDICINE

Megakaryocytic leukemia 1 (MKL1) ties the epigenetic machinery to hypoxia-induced transactivation of endothelin-1

(2013) Yuyu Yang et al.   NUCLEIC ACIDS RESEARCH

UCP1 in Brite/Beige Adipose Tissue Mitochondria Is Functionally Thermogenic

(2013) Irina G. Shabalina et al.   Cell Reports

Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and Obesity

(2012) Marta Derecka et al.   Cell Metabolism

In Vivo Identification of Bipotential Adipocyte Progenitors Recruited by β3-Adrenoceptor Activation and High-Fat Feeding

(2012) Yun-Hee Lee et al.   Cell Metabolism

Plasticity and cross-talk of Interleukin 6-type cytokines

(2012) Christoph Garbers et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Lipolytic Products Activate Peroxisome Proliferator-activated Receptor (PPAR) α and δ in Brown Adipocytes to Match Fatty Acid Oxidation with Supply

(2012) Emilio P. Mottillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signaling Mechanisms That Regulate Smooth Muscle Cell Differentiation

(2011) Christopher P. Mack   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Protection from Obesity and Diabetes by Blockade of TGF-β/Smad3 Signaling

(2011) Hariom Yadav et al.   Cell Metabolism

Transcriptional Control of Adipose Lipid Handling by IRF4

(2011) Jun Eguchi et al.   Cell Metabolism

Desnutrin/ATGL Is Regulated by AMPK and Is Required for a Brown Adipose Phenotype

(2011) Maryam Ahmadian et al.   Cell Metabolism

Differentiation of human adipose-derived stem cells into “brite” (brown-in-white) adipocytes

(2011) Didier F. Pisani   Frontiers in Endocrinology

β3-adrenergic receptor induction of adipocyte inflammation requires lipolytic activation of stress kinases p38 and JNK

(2010) Emilio P. Mottillo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

JAK2/STAT3 pathway is involved in the early stage of adipogenesis through regulatingC/EBPβtranscription

(2010) Kunming Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue

(2010) Aliki Kosteli et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcriptional control of preadipocyte determination by Zfp423

(2010) Rana K. Gupta et al.   NATURE

Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes

(2010) A. Vegiopoulos et al.   SCIENCE

Signal transducer and activator of transcription 3 (STAT3) regulates adipocyte differentiation via peroxisome-proliferator-activated receptor γ (PPARγ)

(2009) Dongmei Wang et al.   BIOLOGY OF THE CELL

Human Multipotent Adipose-Derived Stem Cells Differentiate into Functional Brown Adipocytes

(2009) Christian Elabd et al.   STEM CELLS

Dynamic control of TGF-β signaling and its links to the cytoskeleton

(2008) Aristidis Moustakas et al.   FEBS LETTERS

Examining the Chirality, Conformation and Selective Kinase Inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (CP-690,550)

(2008) Jian-kang Jiang et al.   JOURNAL OF MEDICINAL CHEMISTRY

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

(2008) Yu-Hua Tseng et al.   NATURE