Biologically active azolo-1,2,4-triazines and azolopyrimidines

6-Nitrotriazolo[1,5-a]pyrimidines as promising structures for pharmacotherapy of septic conditions

(2017) K. V. Savateev et al.   RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY

Scientific foundations for the creation of antiviral and antibacterial preparations

(2016) O. N. Chupakhin et al.   HERALD OF THE RUSSIAN ACADEMY OF SCIENCES

New stable form of nitroacetonitrile

(2016) Egor K. Voinkov et al.   MENDELEEV COMMUNICATIONS

Adenosine A2A receptor as a drug target for treatment of sepsis

(2016) K. V. Sivak et al.   MOLECULAR BIOLOGY

Recent advances in the field of nucleophilic aromatic substitution of hydrogen

(2016) Oleg N. Chupakhin et al.   TETRAHEDRON LETTERS

C–H functionalization of triazolo[a]-annulated 8-azapurines

(2016) Evgeny B. Gorbunov et al.   TETRAHEDRON LETTERS

Nucleophilic substitution of nitro group in nitrotriazolotriazines as a model of potential interaction with cysteine-containing proteins

(2015) Vladimir L. Rusinov et al.   Chemistry of Heterocyclic Compounds

Synthesis of 2Н-azolo[1,5-а][1,2,3]triazolo[4,5-е]pyrimidines

(2015) Evgeny B. Gorbunov et al.   Chemistry of Heterocyclic Compounds

Potassium salt of nitroacetonitrile in the synthesis of nitrogen heterocycles

(2015) Egor K. Voinkov et al.   Chemistry of Heterocyclic Compounds

Structural analogs of adenosine receptor inhibitors in the series of 1,2,4-triazolo[1,5-a]pyrimidines

(2015) K. V. Savateev et al.   RUSSIAN CHEMICAL BULLETIN

8-Alkyl[1,2,4]Triazolo[5,1-b]Purines

(2014) K. V. Savateev et al.   Chemistry of Heterocyclic Compounds

Adenosine Receptors: Expression, Function and Regulation

(2014) Sandeep Sheth et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synthesis of acyclic nucleoside analogues based on 1,2,4-triazolo[1,5-a]pyrimidin-7-ones by one-step Vorbrüggen glycosylation

(2014) Igor A. Khalymbadzha et al.   TETRAHEDRON

Long-Range 1H–15N J Couplings Providing a Method for Direct Studies of the Structure and Azide–Tetrazole Equilibrium in a Series of Azido-1,2,4-triazines and Azidopyrimidines

(2013) Tatyana S. Shestakova et al.   JOURNAL OF ORGANIC CHEMISTRY

New Approaches to Sepsis: Molecular Diagnostics and Biomarkers

(2012) K. Reinhart et al.   CLINICAL MICROBIOLOGY REVIEWS

Discovery and pharmacological characterization of N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor

(2011) Noriyasu Kato et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Fluorinated [1,2,4]triazolo[1,5-a]pyrimidines and [1,2,4]triazolo[5,1-c][1,2,4]triazines*

(2011) E. N. Ulomskiy et al.   Chemistry of Heterocyclic Compounds

Synthesis of the [2H,15N]-labeled antiviral drug “triazavirine”

(2011) T. S. Shestakova et al.   RUSSIAN CHEMICAL BULLETIN

Structure of an Agonist-Bound Human A2A Adenosine Receptor

(2011) F. Xu et al.   SCIENCE

Antiviral Properties, Metabolism, and Pharmacokinetics of a Novel Azolo-1,2,4-Triazine-Derived Inhibitor of Influenza A and B Virus Replication

(2010) I. Karpenko et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis and SAR of azolopyrimidines as potent and selective dipeptidyl peptidase-4 (DPP4) inhibitors for type 2 diabetes

(2010) Robert P. Brigance et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1,2,4-Triazoloazine derivatives as a new type of herpes simplex virus inhibitors

(2010) S.L. Deev et al.   BIOORGANIC CHEMISTRY

Non-Natural Nucleosides Based on 1,2,4-Triazolo[1,5-a]pyrimidin-7-ones

(2010) Oleg N. Chupakhin et al.   HETEROCYCLES

The Role of the Transcription Factor CREB in Immune Function

(2010) A. Y. Wen et al.   JOURNAL OF IMMUNOLOGY

Selective15N-Labeling and Analysis of13C−15NJCouplings as an Effective Tool for Studying the Structure and Azide−Tetrazole Equilibrium in a Series of Tetrazolo[1,5-b][1,2,4]triazines and Tetrazolo[1,5-a]pyrimidines

(2010) Sergey L. Deev et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis and antiviral activity of nucleoside analogs based on 1,2,4-triazolo[3,2-c][1,2,4]triazin-7-ones

(2010) V. L. Rusinov et al.   RUSSIAN CHEMICAL BULLETIN

Synthesis of acyclic nucleosides based on 1,2,4-triazolo[3,2-c][1,2,4]triazin-7-ones

(2009) T. S. Shestakova et al.   RUSSIAN CHEMICAL BULLETIN

Azolo[5,1-c]-1,2,4-triazines as a new class of antiviral compounds

(2009) V. L. Rusinov et al.   RUSSIAN CHEMICAL BULLETIN

Adenosine Receptor Antagonists:  Translating Medicinal Chemistry and Pharmacology into Clinical Utility

(2008) Pier Giovanni Baraldi et al.   CHEMICAL REVIEWS

The discovery of antiviral agents: Ten different compounds, ten different stories

(2008) Erik De Clercq   MEDICINAL RESEARCH REVIEWS